Pharmacological Therapy in Neuropathic Bladder

Peningkatan suhu tubuh menyebabkan rasa tidak nyaman, gelisah pada anak, sehingga waktu untuk istirahat menjadi terganggu.Tatalaksana pada anak dengan demam dapat dilakukan dengan metode farmakologi dan non farmakologi. Tepid water spongingmerupakan tatalaksana non farmakologi. Konservasi adalah serangkaian sistem agar tubuh manusia mampu menjalankan fungsi, beradaptasi untuk melangsungkan kehidupan. Perawat mempunyai peran untuk membantu anak dalam mengatasi gangguan termoregulasi. Karya ilmiah ini bertujuan untuk mengetahui efektifitas penurunan suhu tubuh menggunakan tepid water sponging dengan pendekatanl konservasi Levine di ruang rawat infeksi. Efektifitas diukur dalam pemberian asuhan keperawatan berdasarkan proses keperawatan yang terdapat dalam model konservasi Levine yaitu: pengkajian, menentukan trophicognosis, menentukan hipotesis, intervensi dan evaluasi. Terdapat lima kasus yang dibahas. Hasil penerapan model konservasi Levine mampu meningkatkan kemampuan anak dalam mempertahankan fungsi tubuh dan beradaptasi terhadap perubahan. Kombinasi tepid water sponging dan terapi farmakologi mampu mengatasi demam dengan cepat dibanding terapi farmakologi. Kata kunci: termoregulasi, tepid water sponging, teori model konservasi Levine REDUCTION OF BODY TEMPERATURE USING TEPID WATER SPONGINGWITH THE LEVINE CONSERVATION APPROACH ABSTRACT Increased body temperature causes discomfort, anxiety in children, so that the time to rest becomes disturbed. Management of children with fever can be done by pharmacological and non-pharmacological methods. Tepid water sponging is a non-pharmacological treatment. Conservation is a series of systems so that the human body is able to function, adapt to life. Nurses have a role to help children overcome thermoregulation disorders. This scientific work aims to determine the effectiveness of decreasing body temperature using tepid water sponging with the approach of Levine conservation in the infectious care room. Effectiveness is measured in the provision of nursing care based on the nursing process contained in the Levine conservation model, namely: assessment, determining trophicognosis, determining hypotheses, intervention and evaluation. There are five cases discussed. The results of the application of the Levine conservation model are able to improve the ability of children to maintain body functions and adapt to changes. The combination of tepid water sponging and pharmacological therapy is able to overcome fever quickly compared to pharmacological therapy. Keywords: thermoregulation, tepid water sponging, Levine conservation model theory

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Are we ready for pharmacological therapy of obesity?: AGAINST

Endocrine Abstracts ◽

10.1530/endoabs.41.d2.2 ◽

2016 ◽

Author(s):

Uberto Pagotto

Keyword(s):

Pharmacological Therapy

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Non-Pharmacological Therapy for Pregnant Women with Low Back Pain: A Systematic Review

Promoting Population Mental Health and Well-Being ◽

10.26911/theicph.2019.05.21 ◽

2019 ◽

Author(s):

Meliyana Meliyana ◽

◽

Ari Suwondo ◽

Mursid Mursid ◽

◽

...

Keyword(s):

Systematic Review ◽

Low Back Pain ◽

Back Pain ◽

Pregnant Women ◽

Pharmacological Therapy ◽

Low Back

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Application of pharmacological therapy to improve the results of surgical treatment of children with congenital funnel-shaped deformation of the chest

International Journal of Pharmaceutical Research ◽

10.31838/ijpr/2019.11.04.062 ◽

2019 ◽

Vol 11 (4) ◽

Keyword(s):

Surgical Treatment ◽

Pharmacological Therapy

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PENGARUH PEMBERIAN BELIMBING DAN MENTIMUN TERHADAP PENDERITA HIPERTENSI DI DESA LAU KERSIK KECAMATAN GUNUNG SITEMBER KABUPATEN DAIRI

Jurnal Penelitian Keperawatan Medik ◽

10.36656/jpkm.v2i1.189 ◽

2019 ◽

Vol 2 (1) ◽

pp. 18-23

Author(s):

Herri Novita Br Tarigan ◽

Prista Hotmarina Purba

Keyword(s):

Blood Pressure ◽

Data Analysis ◽

Fruit Juice ◽

Blood Pressure Reduction ◽

Reduce Blood Pressure ◽

Pharmacological Therapy ◽

Hypertensive Patients ◽

Star Fruit ◽

Equivalent Time ◽

Life Threatening

Hypertension is a disease that is not uncommon in the community, including the Bukit Lau Kersik village. People with hypertension often do not show long-term symptoms and can be life-threatening. However, one of the management of hypertension that can be used as non-pharmacological therapy is consuming starfruit juice and cucumber which is quite easy to find in the Bukit Lau Kersik village. This combination of juices contains potassium which can reduce blood pressure in patients with hypertension. This study used Equivalent Time Sample Design with 14 subjects with hypertension in the Bukit Lau Kersik Village, Gunung Sitember Subdistrict, Dairi District. The technique of this research sample used Non-Probability Sampling with Saturated Sampling. The instrument used was a sphygmomanometer and a stethoscope. Bivariate data analysis in this study was the Wilcoxon statistical test. Based on the data analysis performed, the value of p = 0.011 (p= < 0.05) was obtained, meaning that there was a significant relationship between giving star fruit juice and cucumber to hypertensive patients. Then it can be concluded that there is an influence between giving star fruit and cucumber juice to blood pressure reduction in hypertensive patients in Bukit Lau Kersik Village Gunung Sitember Subdistrict, Dairi District in 2019. Suggestion: The factors that affect blood pressure in hypertensive patients and checking blood pressure before drinking star fruit juice and cucumber.

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Pharmacological Therapy of Pericardial Diseases

Current Pharmaceutical Design ◽

10.2174/138161282104141204144622 ◽

2014 ◽

Vol 21 (4) ◽

pp. 525-530 ◽

Cited By ~ 3

Author(s):

Massimo Imazio ◽

Yehuda Adler

Keyword(s):

Pharmacological Therapy ◽

Pericardial Diseases

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Efficacy and Cardiovascular Safety of Sulfonylureas

Current Drug Safety ◽

10.2174/1574886315999201125211433 ◽

2020 ◽

Vol 15 ◽

Author(s):

Cornelius James Fernandez ◽

Raveendran Arkiath Veettil ◽

Nyi Htwe

Keyword(s):

Regulatory Authority ◽

Microvascular Complications ◽

Pharmacological Therapy ◽

Cardiovascular Safety ◽

Lifestyle Modifications ◽

First Line ◽

Considerable Uncertainty ◽

Cardiovascular Outcome Trials ◽

Metformin Monotherapy ◽

Control And Prevention

Abstract:: There is universal agreement that when lifestyle modifications are inadequate to control the hyperglycemia, metformin should be considered as the first line pharmacological therapy. However, when metformin monotherapy fails, there is no consensus as to which drug should be added. Many new classes of drugs that are currently available including DPP-4 inhibitors, GLP-1 agonists and SGLT-2 inhibitors have undergone cardiovascular outcome trials which had been made mandatory by the regulatory authority and thereby established their cardiovascular safety or at least neutrality. Though sulfonylureas are one of the widely prescribed drugs both in developed and developing countries and have proven their efficacy for glycemic control and prevention of microvascular complications, there is considerable uncertainty about its cardiovascular safety which has been going on for nearly five decades. In this review we will critically analyze the efficacy and cardiovascular safety of sulphonylurea, based on the latest available literature to clarify their role in our day-to-day clinical practice.

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Nostra esperienza nell'utilizzo dell'associazione PgE1 e Ketanserina in farmacoprotesi

Urologia Journal ◽

10.1177/039156039406101s58 ◽

1994 ◽

Vol 61 (1_suppl) ◽

pp. 198-200

Author(s):

A. Raimoldi ◽

G.L. Berti ◽

V. Giola ◽

G.L. Leidi ◽

A. Maccaroni ◽

...

Keyword(s):

Side Effect ◽

Pharmacological Therapy ◽

Maximum Dosage ◽

Hypotensive Episode

The authors assessed the effectiveness of an association of prostaglandins (PgE1) and Ketanserine (K) in pharmacoprosthesis on 24 patients with erectile deficiency of various etiology. The association of 20 mcgr of PgE1 with K (from 2 to 6 mg) was more effective in inducing erection than only PgE1 at 40 mcgr dosage; in 3 patients the effectiveness was relatively equivalent. No relevant side effect was found except for a transitory hypotensive episode in a patient when the K maximum dosage was reached, which was resolved without the help of pharmacological therapy. Consequently, K can certainly be considered capable of strengthening the action of the PgE1 in inducing erection and, therefore, can be usefully associated with the latter whenever either a satisfactory erection hasn't taken place or the PgE1 dosage is to be reduced in order to lower costs.

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Treatment of a Critically Ill COVID-19 Patient with the Seraph 100 Microbind Affinity Filter

TH Open ◽

10.1055/s-0041-1727121 ◽

2021 ◽

Vol 05 (02) ◽

pp. e134-e138

Author(s):

Anke Pape ◽

Jan T. Kielstein ◽

Tillman Krüger ◽

Thomas Fühner ◽

Reinhard Brunkhorst

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Critically Ill ◽

Critically Ill Patients ◽

Randomized Trials ◽

Clinical Course ◽

Pharmacological Therapy ◽

The European Union ◽

Positive Effects ◽

Special Patient

AbstractThe coronavirus disease 2019 (COVID-19) pandemic has a serious impact on health and economics worldwide. Even though the majority of patients present with moderate and mild symptoms, yet a considerable portion of patients need to be treated in the intensive care unit. Aside from dexamethasone, there is no established pharmacological therapy. Moreover, some of the currently tested drugs are contraindicated for special patient populations like remdesivir for patients with severely impaired renal function. On this background, several extracorporeal treatments are currently explored concerning their potential to improve the clinical course and outcome of critically ill patients with COVID-19. Here, we report the use of the Seraph 100 Microbind Affinity filter, which is licensed in the European Union for the removal of pathogens. Authorization for emergency use in patients with COVID-19 admitted to the intensive care unit with confirmed or imminent respiratory failure was granted by the U.S. Food and Drug Administration on April 17, 2020.A 53-year-old Caucasian male with a severe COVID-19 infection was treated with a Seraph Microbind Affinity filter hemoperfusion after clinical deterioration and commencement of mechanical ventilation. The 70-minute treatment at a blood flow of 200 mL/minute was well tolerated, and the patient was hemodynamically stable. The hemoperfusion reduced D-dimers dramatically.This case report suggests that the use of Seraph 100 Microbind Affinity filter hemoperfusion might have positive effects on the clinical course of critically ill patients with COVID-19. However, future prospective collection of data ideally in randomized trials will have to confirm whether the use of Seraph 100 Microbind Affinity filter hemoperfusion is an option of the treatment for COVID-19.

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