Etiological Factors

1983 ◽  
pp. 41-63
Author(s):  
Diane J. Willis ◽  
B. Marion Swanson ◽  
C. Eugene Walker
Keyword(s):  
Etiological Factors

Matrix metalloproteinases: structure, functions and genetic polymorphism

2017 ◽  
pp. 14-23
Author(s):  
А.С. Шадрина ◽  
И.В. Терешкина ◽  
Я.З. Плиева ◽  
Д.Н. Кушлинский ◽  
Д.О. Уткин ◽  
...  
Keyword(s):  
Genetic Polymorphism ◽  
Matrix Metalloproteinases ◽  
Active Center ◽  
Human Body ◽  
Enzymatic Catalysis ◽  
Structure Functions ◽  
Zinc Ion ◽  
Etiological Factors ◽  
Mmp Genes

Матриксные металлопротеиназы (ММП) - ферменты класса гидролаз, осуществляющие ферментативный катализ с помощью связанного в активном центре иона цинка. Функции ММП разнообразны, и нарушение баланса их активности может быть одним из этиологических факторов различных заболеваний. В данном обзоре рассмотрена классификация ММП человека, особенности их структуры и регуляции, а также роль в физиологических и патологических процессах в организме человека. Приведен перечень наиболее изученных на настоящий момент полиморфных вариантов генов MMП, описаны их функциональные эффекты и представлены результаты ассоциативных исследований. Matrix metalloproteinases (MMPs) are enzymes of the hydrolase class that carry out enzymatic catalysis with the help of a zinc ion bound in the active center. MMP functions are diverse, and a disturbance in the balance of their activity may be one of the etiological factors of various diseases. In this review, the classification of human MMP, the features of their structure and regulation, as well as the role in physiological and pathological processes in the human body are considered. A list of the most studied polymorphic versions of MMP genes has been given, their functional effects have been described, and the results of associative studies have been presented.

Gingival recession and periodontal therapy

2019 ◽  
Vol 31 (1) ◽  
pp. 31-36
Author(s):  
Monya N. Hassan ◽  
Maha A. Aziz
Keyword(s):  
Gingival Recession ◽  
Root Surface ◽  
Periodontal Therapy ◽  
Etiological Factors ◽  
Gingival Margin

Background: Gingival recession is defined as the apical migration of the gingival margin below the cementoenamel junction (CEJ), resulting in exposure of the root surface and it is one of the main esthetic complaints of patients. The management of gingival recession and its sequelae is based on a thorough assessment of the etiological factors and the degree of tissue involvement.

AYURVEDIC PREPARATIONS FOR THE MANAGEMENT OF THE RAS - A REVIEW

2020 ◽  
Vol 7 (9) ◽  
pp. 1-8
Keyword(s):  
General Population ◽  
Herbal Medicines ◽  
Sudden Increase ◽  
Herbal Extracts ◽  
Common Condition ◽  
Etiological Factors ◽  
Oral Ulcers ◽  
Alternative Approach

Oral ulcers are the most common condition in the general population and are caused by a variety of etiological factors. It often causes pain and discomfort. So, there are different treatments including herbal medicines that have been used for oral ulcers. Nowadays, there has been a sudden increase in the use of herbal extracts as an alternative approach to modern-day medicines. So, this review focuses on the ayurvedic preparations for the treatment of RAS.

SPECIFICITY OF THE CLINICAL COURSE OF THE INITIAL STAGES OF HYPERTENSION IN ARID ZONES OF UZBEKISTAN AND NON-DRUG APPROACHES TO TREATMENT

2020 ◽  
Author(s):  
U.R. Narzulaeva ◽  
G.U. Samieva ◽  
M.Sh. Ismatova
Keyword(s):  
At Risk ◽  
Drug Treatment ◽  
Healthy Lifestyle ◽  
Clinical Course ◽  
Arid Zones ◽  
Etiological Factors ◽  
Renin Angiotensin ◽  
Early Stages ◽  
Hot Climate ◽  
Patients At Risk

The article describes the etiological factors, the course and risks of the development of hypertension in the early stages in a hot climate. The data on the pathogenesis of hypertension and the effects of pathogenetic variants of the sympatho-adrenal and renin-angiotensin systems are summarized. Non-drug treatment is proposed by observing a healthy lifestyle in patients at risk.

ETIOLOGICAL FACTORS OF SQUAMOUS CELL CANCER OF THE MUCOUS MEMBRANE OF THE ORAL CAVITY

2017 ◽  
Vol 63 (5) ◽  
pp. 703-707
Author(s):  
Vladimir Nikolenko ◽  
Yekaterina Kochurova ◽  
Aleksandr Mukhanov
Keyword(s):  
Oral Cavity ◽  
Mucous Membrane ◽  
Squamous Cell ◽  
Preventive Measures ◽  
Causal Relation ◽  
Cell Cancer ◽  
General Assumption ◽  
Etiological Factors ◽  
Long Acting ◽  
Potential Pathogenicity

Modern data of the etiology of squamous cell carcinoma (SCC) of the mucous membrane of the oral cavity (MMOC) show an increasing prevalence of the disease, a high mortality rate despite the development of modern methods of diagnosis and treatment. SCC is a group of polyetiological diseases. Among the most often etiological factors the use of tobacco products is found as one of the main cause of the disease with the division into active or passive methods of their use, prevalence and potential pathogenicity. Also the risk of the development of SCC MMOC depends on the consumption of alcoholic product as the long-acting traumatic factor. There were analyzed and considered the most common precancerous diseases of the mucous membrane of the mouth, their private and common significance in the structure of precancerous diseases. There was revealed the high correlation between periodontal disease and the development of SCC MMOC, which corresponded to the general assumption about the risk of oncology development against the background of chronic infection in the oral cavity. There were identified new data of the relation between the carriers of some types of the viruses of human papillomavirus and the development of SCC MMOC. Particular understanding of the causal relation of presented on-copathology allowed judging the lack of preventive measures, the necessity of required qualification of specialists of dental and related profile.

scholarly journals Knowledge Gaps in Understanding the Etiology of Anemia in Indonesian Adolescents

2021 ◽  
Vol 42 (1_suppl) ◽  
pp. S39-S58
Author(s):  
Kesso Gabrielle van Zutphen ◽  
Klaus Kraemer ◽  
Alida Melse-Boonstra
Keyword(s):  
Current Knowledge ◽  
Vitamin A Deficiency ◽  
Public Health Problem ◽  
Population Group ◽  
Future Research ◽  
Folic Acid Deficiency ◽  
Knowledge Gaps ◽  
Local Conditions ◽  
Etiological Factors ◽  
Infection And Inflammation

Background: Anemia is a public health problem among adolescents in Indonesia. Strategies to prevent or treat anemia should be tailored to local conditions, taking into account its specific etiology and prevalence in a given setting and population group. Objective: This review aims to (1) identify and synthesize the current knowledge on the etiology of anemia among adolescents in Indonesia, (2) reveal knowledge gaps in this area, and (3) suggest directions for future research and programmatic work. Methods: We systematically searched PubMed, Web of Science, Scopus, Medline, and WorldCat databases for peer-reviewed journal articles to identify which etiological factors were related to anemia among Indonesian adolescents. Research papers were reviewed and included in the review according to inclusion criteria. Results: Of 13 studies, 8 showed that anemia was associated with iron deficiency; 4 are suggestive of vitamin A deficiency; and 2 of folic acid deficiency. Five studies underscore different etiological determinants for anemia, such as malaria, protein and energy malnutrition, vitamin B2 deficiency, calcium, and vitamin C deficiency. Based on these findings, we developed a framework on knowledge gaps on the etiology of anemia among adolescents in Indonesia, divided in 3 levels of knowledge: (1) significant knowledge gaps, (2) knowledge gaps, and (3) established knowledge. Conclusions: The knowledge gaps around the etiology of anemia among Indonesian adolescents are significant. Our framework emphasizes the need for further research across all etiological factors, namely inadequate nutritional intake and absorption, genetic hemoglobin disorders, infection and inflammation, and menstrual disorders.

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