Making the Right Choice: Critical Parameters of the Y2H Systems

2018 ◽  
pp. 17-28 ◽  
Author(s):  
Jitender Mehla ◽  
J. Harry Caufield ◽  
Peter Uetz
Keyword(s):  
Critical Parameters ◽  
The Right

scholarly journals The Effect of Low Friction in Pavement Due to Floods and High-speed Vehicles in Increasing the Number of Rescue Vehicles' Driving Accidents

2020 ◽  
Vol 6 (1) ◽  
pp. 29-38
Author(s):  
Mohammad Mehdi Khabiri ◽  
◽  
Zohrah Ghaforifard ◽  
Keyword(s):  
Natural Disasters ◽  
High Speed ◽  
Traffic Accidents ◽  
Probabilistic Method ◽  
Geometric Design ◽  
Critical Parameters ◽  
Rescue Operation ◽  
Curve Length ◽  
Speed Parameter ◽  
The Right

Background: The rescue operation is dangerous during floods when the street surface is wet and the rescue vehicles moving fast. Rural roads are known with a high percentage of run-off-the-road crashes and accidents, mostly affected by the unsuitable and inappropriate speed of the car and failure to keep a safe side distance from the highway alignment. Determining the length of the vertical curve and the stopping distance depends on the speed parameter in the geometric design. This parameter depends on the traffic flow and the vehicle driver. Materials and Methods: The calculation of distance visibility, especially in the vertical and horizontal curves, has a significant role in the geometric design of roads and the safety of roads and drivers. This study investigates changes in two critical parameters of friction surface of pavement and vehicles’ speed on the probability of accidents. In the present study, by changing the speed parameter, namely, increasing speed and decreasing friction, and reducing the distance of vision, the required vertical curve is calculated and compared with the existing curve length. Thus, when the curve length does not match the required arch length, the accident’s probability increases. Results: One of the study’s findings indicates that with a 5% decrease in the friction coefficient of the vertical curve, the probability of accident increases by about 20%. The results show that an approximately 10% increase in speed can raise the likelihood of a crash by 25% on average. Conclusion: The use of accident reduction-related strategies for rescue vehicles and ambulances will help the victims affected by natural disasters. The results showed that choosing the right speed is very important in flooded wet streets. Driving fast to speed up the relief operation not only increases the risk of traffic accidents but also slows down the relief of natural disasters. The results indicate the proper performance of the model created by the probabilistic method. Besides, this model’s use has the advantage of correctly identifying the factors affecting the increase in risk. Also, it helps to take the right measures to increase safety in the relief of natural disasters, especially floods.

scholarly journals BEGA – ANDROID-BASED BEERGAME SIMULATION SOFTWARE FOR INTERACTIVE TRAINING AND INNOVATION

2013 ◽  
Vol 21 (33) ◽  
pp. 14-20
Author(s):  
Katarína Lestyánszka Škůrková ◽  
Norina Szander
Keyword(s):  
Supply Chain ◽  
Balanced Scorecard ◽  
Life Experience ◽  
Real Life ◽  
Bullwhip Effect ◽  
Simulation Software ◽  
Critical Parameters ◽  
Performance Measurement System ◽  
Software Application ◽  
The Right

Abstract The supply chain management challenges and inventory holding problems can easily be demonstrated by the widely known BeerGame simulation. In the Szabó-Szoba R&D Laboratory, we developed an android-based software application for tablets and smart phones for the purpose of having an adaptable, entertaining and effective program which can provide a real life experience to the participants about the nature of the bullwhip effect. Having an appropriate and comprehensive performance measurement system with the critical parameters and KPIs is inevitable for finding the right solutions - We used four perspectives of the Balanced Scorecard method. The innovative force of our research is based on the trainings: the discussion on outcomes and the team learning. The purpose of the current development is to build a new feature in the software: an artificial client can substitute one or more players in the supply chain, which makes decisions by using genetic algorithms.

Investor-State Dispute Settlement under NAFTA Chapter 11: The Shape of Things to Come?

1998 ◽  
Vol 35 ◽  
pp. 263-290
Author(s):  
J. Anthony VanDuzer
Keyword(s):  
Free Trade Agreement ◽  
Dispute Settlement ◽  
Trade Agreement ◽  
Minimum Standards ◽  
The North ◽  
State Behaviour ◽  
Nafta Chapter 11 ◽  
To Come ◽  
The Right

SummaryRecently, there has been a proliferation of international agreements imposing minimum standards on states in respect of their treatment of foreign investors and allowing investors to initiate dispute settlement proceedings where a state violates these standards. Of greatest significance to Canada is Chapter 11 of the North American Free Trade Agreement, which provides both standards for state behaviour and the right to initiate binding arbitration. Since 1996, four cases have been brought under Chapter 11. This note describes the Chapter 11 process and suggests some of the issues that may arise as it is increasingly resorted to by investors.

What face familiarity feelings say about the lateralization of specific entities within the core system

2019 ◽  
Vol 42 ◽  
Author(s):  
Guido Gainotti
Keyword(s):  
Temporal Lobe ◽  
Memory System ◽  
Core System ◽  
The Core ◽  
Memory Traces ◽  
Specific Memory ◽  
Target Article ◽  
Temporal Structures ◽  
The Right

Abstract The target article carefully describes the memory system, centered on the temporal lobe that builds specific memory traces. It does not, however, mention the laterality effects that exist within this system. This commentary briefly surveys evidence showing that clear asymmetries exist within the temporal lobe structures subserving the core system and that the right temporal structures mainly underpin face familiarity feelings.

Study of charge transfer in FeTi

1983 ◽  
Vol 41 ◽  
pp. 296-297
Author(s):  
J. Taft∅
Keyword(s):  
Charge Transfer ◽  
Charge Distribution ◽  
Electron Scattering ◽  
Periodic System ◽  
Electron Distribution ◽  
Scattering Amplitude ◽  
Transition Elements ◽  
Hartree Fock ◽  
Cscl Structure ◽  
The Right

It is well known that for reflections corresponding to large interplanar spacings (i.e., sin θ/λ small), the electron scattering amplitude, f, is sensitive to the ionicity and to the charge distribution around the atoms. We have used this in order to obtain information about the charge distribution in FeTi, which is a candidate for storage of hydrogen. Our goal is to study the changes in electron distribution in the presence of hydrogen, and also the ionicity of hydrogen in metals, but so far our study has been limited to pure FeTi. FeTi has the CsCl structure and thus Fe and Ti scatter with a phase difference of π into the 100-ref lections. Because Fe (Z = 26) is higher in the periodic system than Ti (Z = 22), an immediate “guess” would be that Fe has a larger scattering amplitude than Ti. However, relativistic Hartree-Fock calculations show that the opposite is the case for the 100-reflection. An explanation for this may be sought in the stronger localization of the d-electrons of the first row transition elements when moving to the right in the periodic table. The tabulated difference between fTi (100) and ffe (100) is small, however, and based on the values of the scattering amplitude for isolated atoms, the kinematical intensity of the 100-reflection is only 5.10-4 of the intensity of the 200-reflection.

New Dimensions in Freeze-Etching

1969 ◽  
Vol 27 ◽  
pp. 202-203 ◽  
Author(s):  
Russell L. Steere ◽  
Michael Moseley
Keyword(s):  
Fracture Surfaces ◽  
Aluminum Specimen ◽  
Specimen Holder ◽  
Freeze Etching ◽  
The Right

A redesigned specimen holder and cap have made possible the freeze-etching of both fracture surfaces of a frozen fractured specimen. In principal, the procedure involves freezing a specimen between two specimen holders (as shown in A, Fig. 1, and the left side of Fig. 2). The aluminum specimen holders and brass cap are constructed so that the upper specimen holder can be forced loose, turned over, and pressed down firmly against the specimen stage to a position represented by B, Fig. 1, and the right side of Fig. 2.

Adrenocorticotropin Production by a Mammary Carcinoma

1977 ◽  
Vol 35 ◽  
pp. 462-463
Author(s):  
K.S. McCarty ◽  
N.R. Wallace ◽  
W. Litaker ◽  
S. Wells ◽  
G. Eisenbarth
Keyword(s):  
Adrenocorticotropic Hormone ◽  
Small Cell ◽  
Hormone Production ◽  
Carcinoma Of The Breast ◽  
Ectopic Acth ◽  
Ultrastructural Studies ◽  
Subcutaneous Metastases ◽  
Ectopic Acth Production ◽  
The Right ◽  
Pituitary Carcinomas

The production of adrenocorticotropic hormone by non-pituitary carcinomas has been documented in several tumors, most frequently small cell carcinoma of the lung, islet cell carcinomas of the pancreas, thymomas and carcinoids. Electron microscopy of these tumors reveals typical membrane-limited "neurosecretory" granules. Confirmation of the granules as adrenocorticotropin (ACTH) requires the use of OsO4 as a primary fixative to give the characteristic cored granule appearance in conjunction with immunohistochemical demonstration of the hormone peptide. Because of the rarity of ectopic ACTH production by mammary carcinomas and the absence of appropriate ultrastructural studies in the two examples of such ectopic hormone production in the literature of which we are aware (1,2), we present biochemical and ultrastructural data from a carcinoma of the breast with apparent ACTH production.The patient had her primary tumor in the right breast in 1969. The tumor recurred as visceral and subcutaneous metastases in 1976 and again in 1977.

Z-line degradation and phagocytosis of sarcomeric fragments in myonecrosis

1983 ◽  
Vol 41 ◽  
pp. 790-791
Author(s):  
Melinda L. Estes ◽  
Samuel M. Chou
Keyword(s):  
Vastus Lateralis ◽  
Inflammatory Myopathy ◽  
Muscle Disease ◽  
White Female ◽  
Inflammatory Cell Infiltrate ◽  
Limb Weakness ◽  
Muscle Diseases ◽  
History Of ◽  
The Right ◽  
Mononuclear Inflammatory Cell

Many muscle diseases show common pathological features although their etiology is different. In primary muscle diseases a characteristic finding is myofiber necrosis. The mechanism of myonecrosis is unknown. Polymyositis is a primary muscle disease characterized by acute and subacute degeneration as well as regeneration of muscle fibers coupled with an inflammatory infiltrate. We present a case of polymyositis with unusual ultrastructural features indicative of the basic pathogenetic process involved in myonecrosis.The patient is a 63-year-old white female with a one history of proximal limb weakness, weight loss and fatigue. Examination revealed mild proximal weakness and diminished deep tendon reflexes. Her creatine kinase was 1800 mU/ml (normal < 140 mU/ml) and electromyography was consistent with an inflammatory myopathy which was verified by light microscopy on biopsy muscle. Ultrastructural study of necrotizing myofiber, from the right vastus lateralis, showed: (1) degradation of the Z-lines with preservation of the adjacent Abands including M-lines and H-bands, (Fig. 1), (2) fracture of the sarcomeres at the I-bands with disappearance of the Z-lines, (Fig. 2), (3) fragmented sarcomeres without I-bands, engulfed by invading phagocytes, (Fig. 3, a & b ), and (4) mononuclear inflammatory cell infiltrate in the endomysium.

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