scholarly journals Early Life Events and Later Life Health: Twin and Famine Studies

2019 ◽  
pp. 311-317 ◽  
Author(s):  
Kaare Christensen
Keyword(s):  
Life Events ◽  
Early Life ◽  
Later Life ◽  
Early Life Events

scholarly journals Early-life nutritional effects on the female reproductive system

2014 ◽  
Vol 224 (2) ◽  
pp. R45-R62 ◽  
Author(s):  
K A Chan ◽  
M W Tsoulis ◽  
D M Sloboda
Keyword(s):  
Life Events ◽  
Reproductive System ◽  
Early Life ◽  
Experimental Studies ◽  
Later Life ◽  
Developmental Trajectory ◽  
Female Reproductive System ◽  
Postnatal Environment ◽  
And Function ◽  
Early Life Events

There is now considerable epidemiological and experimental evidence indicating that early-life environmental conditions, including nutrition, affect subsequent development in later life. These conditions induce highly integrated responses in endocrine-related homeostasis, resulting in persistent changes in the developmental trajectory producing an altered adult phenotype. Early-life events trigger processes that prepare the individual for particular circumstances that are anticipated in the postnatal environment. However, where the intrauterine and postnatal environments differ markedly, such modifications to the developmental trajectory may prove maladaptive in later life. Reproductive maturation and function are similarly influenced by early-life events. This should not be surprising, because the primordial follicle pool is established early in life and is thus vulnerable to early-life events. Results of clinical and experimental studies have indicated that early-life adversity is associated with a decline in ovarian follicular reserve, changes in ovulation rates, and altered age at onset of puberty. However, the underlying mechanisms regulating the relationship between the early-life developmental environment and postnatal reproductive development and function are unclear. This review examines the evidence linking early-life nutrition and effects on the female reproductive system, bringing together clinical observations in humans and experimental data from targeted animal models.

scholarly journals Exploring early life events including diet in cats presenting for gastrointestinal signs in later life

2019 ◽  
Vol 185 (5) ◽  
pp. 144-144 ◽  
Author(s):  
Aarti Kathrani ◽  
Emily Jayne Blackwell ◽  
Jessica L Williams ◽  
Tim Gruffydd-Jones ◽  
Jane K Murray ◽  
...  
Keyword(s):  
Life Events ◽  
Early Life ◽  
Odds Ratio ◽  
Small Animal ◽  
Later Life ◽  
Commercial Diet ◽  
The World ◽  
Nutrition Committee ◽  
Early Life Events ◽  
Global Nutrition

Our study aimed to determine if certain early life events were more prevalent in cats presenting to veterinary practices specifically for gastrointestinal signs on at least two occasions between six months and 30 months of age. Data from an owner-completed questionnaire for 1212 cats before 16 weeks of age and subsequent questionnaires for the same cats between six months and 30 months of age were reviewed. Of the 1212 cats included, 30 visited a veterinary practice for gastrointestinal signs on two or more occasions. Of the early life events recorded, cats reported with vomiting, diarrhoea or both, and/or those not exclusively fed commercial diet(s) that meets the World Small Animal Veterinary Association (WSAVA) Global Nutrition Committee (GNC) guidelines before 16 weeks of age were more likely to visit veterinary practices specifically for gastrointestinal signs on at least two occasions between six months and 30 months of age (P<0.001, odds ratio (OR)=2.64, 95 per cent confidence interval (CI)=1.66–4.22 and P=0.030, OR=1.51, 95 per cent CI=1.04–2.22, respectively). Ensuring cats exclusively consume commercial diet(s) that meets the WSAVA GNC guidelines and further studies identifying specific aetiologies for vomiting and diarrhoea before 16 weeks of age to enable prevention may reduce the number of cats subsequently presenting to primary care veterinary practices for repeated gastrointestinal signs.

Early-life events. Effects on aging

HORMONES ◽  
2008 ◽  
Vol 7 (2) ◽  
pp. 101-113 ◽  
Author(s):  
Eero Kajantie
Keyword(s):  
Life Events ◽  
Early Life ◽  
Early Life Events

The developing world of DOHaD

2017 ◽  
Vol 9 (3) ◽  
pp. 266-269 ◽  
Author(s):  
K. Suzuki
Keyword(s):  
Life Events ◽  
Early Life ◽  
Developing World ◽  
Biomedical Science ◽  
Developmental Origins ◽  
Health And Disease ◽  
Early Life Events

Since its debut in a ground-breaking report by Barker and Osmond in 1986, the concept of the Developmental Origins of Health and Disease (DOHaD) has been further developed in several aspects. Its methodology and conclusions relating to proposed origins and outcomes of early life events have been developing and spreading internationally. Indeed, the DOHaD concept now seems to have influenced many fields of research. This article aims to briefly review why the DOHaD concept is important in biomedical science, how it has developed, is currently developing, and how it should develop in future.

Early life events and later risk of colorectal cancer: age-period-cohort modelling in the Nordic countries and Estonia

2005 ◽  
Vol 16 (3) ◽  
pp. 215-223 ◽  
Author(s):  
E. Svensson ◽  
B. Møller ◽  
S. Tretli ◽  
L. Barlow ◽  
G. Engholm ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Life Events ◽  
Early Life ◽  
Nordic Countries ◽  
Early Life Events

Early life events and motor development in childhood and adolescence: a longitudinal study

2016 ◽  
Vol 105 (5) ◽  
pp. e219-e227 ◽  
Author(s):  
Tegan Grace ◽  
Max Bulsara ◽  
Monique Robinson ◽  
Beth Hands
Keyword(s):  
Longitudinal Study ◽  
Life Events ◽  
Motor Development ◽  
Early Life ◽  
Childhood And Adolescence ◽  
Early Life Events
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