A Cell Manipulation Method Based on Stagnation Point of Swirl

2019 ◽  
pp. 157-165
Author(s):  
Zhiming Ou ◽  
Qin Zhang ◽  
Hao Yang
Keyword(s):  
Stagnation Point ◽  
Cell Manipulation ◽  
A Cell

scholarly journals Real-Time Temperature Detection Via Quantum Dots for Photothermal Cellular Actuation

Proceedings ◽  
2021 ◽  
Vol 56 (1) ◽  
pp. 40
Author(s):  
Wei Yu ◽  
Olivier Deschaume ◽  
Stijn Jooken ◽  
Fanglei Guo ◽  
Pengfei Zhang ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Metal Nanoparticles ◽  
Specific Area ◽  
Cell Manipulation ◽  
Structured Illumination ◽  
Temperature Detection ◽  
Optical Heating ◽  
A Cell ◽  
Plasmonic Heating ◽  
Set Up

Plasmonic heating finds multiple applications in cell manipulation and stimulation, where heat generated by metal nanoparticles can be used to modify cell adhesion, control membrane currents, and suppress neuronal action potentials among others. Metal nanoparticles can also be easily integrated in artificial extracellular matrices to provide tunable, thermal cueing functionalities with nanometer spatial resolution. In this contribution, we present a platform enabling the combination of plasmonic heating with localized temperature sensing using quantum dots (QDs). Specifically, a functional nanocomposite material was designed with gold nanorods (AuNRs) and QDs incorporated in a cell-permissive hydrogel (e.g., collagen) as well as an optical set-up combining optical heating and temperature imaging, respectively. Specific area stimulation/readout can be realized through structured illumination using digital micromirror device (DMD) projection.

Realisation of a Cell Manipulation Bio-Microsystem using Shadow mask techniques

2000 ◽  
pp. 123-126
Author(s):  
A. Tixier ◽  
Y. Mita ◽  
B. Le Pioufle ◽  
P. Surbled ◽  
Y. Murakami ◽  
...  
Keyword(s):  
Cell Manipulation ◽  
Shadow Mask ◽  
A Cell

scholarly journals Tele–Robotic Platform for Dexterous Optical Single-Cell Manipulation

Micromachines ◽  
2019 ◽  
Vol 10 (10) ◽  
pp. 677 ◽  
Author(s):  
Edison Gerena ◽  
Florent Legendre ◽  
Akshay Molawade ◽  
Youen Vitry ◽  
Stéphane Régnier ◽  
...  
Keyword(s):  
Single Cell ◽  
Optical Tweezers ◽  
Biomedical Applications ◽  
High Speed ◽  
Cell Manipulation ◽  
Optical Traps ◽  
A Cell ◽  
Six Dof ◽  
Master Device ◽  
Single Cell Manipulation

Single-cell manipulation is considered a key technology in biomedical research. However, the lack of intuitive and effective systems makes this technology less accessible. We propose a new tele–robotic solution for dexterous cell manipulation through optical tweezers. A slave-device consists of a combination of robot-assisted stages and a high-speed multi-trap technique. It allows for the manipulation of more than 15 optical traps in a large workspace with nanometric resolution. A master-device (6+1 degree of freedom (DoF)) is employed to control the 3D position of optical traps in different arrangements for specific purposes. Precision and efficiency studies are carried out with trajectory control tasks. Three state-of-the-art experiments were performed to verify the efficiency of the proposed platform. First, the reliable 3D rotation of a cell is demonstrated. Secondly, a six-DoF teleoperated optical-robot is used to transport a cluster of cells. Finally, a single-cell is dexterously manipulated through an optical-robot with a fork end-effector. Results illustrate the capability to perform complex tasks in efficient and intuitive ways, opening possibilities for new biomedical applications.

scholarly journals Cell Docking, Movement and Cell-Cell Interactions of Heterogeneous Cell Suspensions in a Cell Manipulation Microdevice

Sensors ◽  
2011 ◽  
Vol 11 (10) ◽  
pp. 9613-9627 ◽  
Author(s):  
Fei-Lung Lai ◽  
Yu-Hung Wang ◽  
Yu-Wei Chung ◽  
Shiaw-Min Hwang ◽  
Long-Sun Huang
Keyword(s):  
Cell Suspensions ◽  
Cell Interactions ◽  
Cell Manipulation ◽  
A Cell ◽  
Cell Cell

scholarly journals Characterization and Separation of Live and Dead Yeast Cells Using CMOS-Based DEP Microfluidics

Micromachines ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 270
Author(s):  
Honeyeh Matbaechi Ettehad ◽  
Christian Wenger
Keyword(s):  
Cell Separation ◽  
Microfluidic Channel ◽  
Microfluidic System ◽  
Yeast Cells ◽  
Cell Manipulation ◽  
Cmos Process ◽  
Label Free ◽  
Electrode Arrays ◽  
A Cell ◽  
Silicon Based

This study aims at developing a miniaturized CMOS integrated silicon-based microfluidic system, compatible with a standard CMOS process, to enable the characterization, and separation of live and dead yeast cells (as model bio-particle organisms) in a cell mixture using the DEP technique. DEP offers excellent benefits in terms of cost, operational power, and especially easy electrode integration with the CMOS architecture, and requiring label-free sample preparation. This can increase the likeliness of using DEP in practical settings. In this work the DEP force was generated using an interdigitated electrode arrays (IDEs) placed on the bottom of a CMOS-based silicon microfluidic channel. This system was primarily used for the immobilization of yeast cells using DEP. This study validated the system for cell separation applications based on the distinct responses of live and dead cells and their surrounding media. The findings confirmed the device’s capability for efficient, rapid and selective cell separation. The viability of this CMOS embedded microfluidic for dielectrophoretic cell manipulation applications and compatibility of the dielectrophoretic structure with CMOS production line and electronics, enabling its future commercially mass production.

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