Frailty Assessment as Measurement of Physiologic Reserves in the Elderly

Author(s):  
Kartik Prabhakaran ◽  
David J. Samson ◽  
Rifat Latifi
Author(s):  
Nawapong Chumha ◽  
Sujitra Funsueb ◽  
Sila Kittiwachana ◽  
Pimonpan Rattanapattanakul ◽  
Peerasak Lerttrakarnnon

Frailty, one of the major public health problems in the elderly, can result from multiple etiologic factors including biological and physical changes in the body which contribute to the reduction in the function of multiple bodily systems. A diagnosis of frailty can be reached using a variety of frailty assessment tools. In this study, general characteristics and health data were assessed using modified versions of Fried’s Frailty Phenotype (mFFP) and the Frail Non-Disabled (FiND) questionnaire (mFiND) to construct a Self-Organizing Map (SOM). Trained data, composed of the component planes of each variable, were visualized using 2-dimentional hexagonal grid maps. The relationship between the variables and the final SOM was then investigated. The SOM model using the modified FiND questionnaire showed a correct classification rate (%CC) of about 66% rather than the model responded to mFFP models. The SOM Discrimination Index (SOMDI) identified cataracts/glaucoma, age, sex, stroke, polypharmacy, gout, and sufficiency of income, in that order, as the top frailty-associated factors. The SOM model, based on the mFiND questionnaire frailty assessment, is an appropriate tool for assessment of frailty in the Thai elderly. Cataracts/glaucoma, stroke, polypharmacy, and gout are all modifiable early prediction factors of frailty in the Thai elderly.


10.3823/2404 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Graciela Maria Carneiro Maciel ◽  
Heloiza Talita Adriano da Silva ◽  
Rafaella Guilherme Gonçalves ◽  
Josefa Danielma Lopes Ferreira ◽  
Sarah Vinagre Tietre ◽  
...  

Background: Frailty assessment in the elderly and its relationship to sociodemographic and health characteristics. Method: Quantitative study, descriptive and cross-sectional study, conducted between April to July 2014, at two Family Health Units in Natal, Rio Grande do Norte. The sample consisted of 203 elderly. The data collection procedure occurred through a structured interview, which used two instruments. Results: The average age of the participants was 68.59 years; among them, 83 (40.89%) did not show weakness, 45 (22.17%) were apparently vulnerable and 75 (36.94%) were frail. The weakness associated with low education, widowhood, heart disease, diabetes mellitus, osteoporosis, respiratory disease, urinary tract infection, depression, six classes of drugs (antidiabetic, antidepressant, anxiolytic, and antacid against osteoporosis) and fall episode. Conclusions: We conclude that assessment of frailty is important to detect the risk and/or embrittlement process already installed in the elderly.


2020 ◽  
Vol 13 (2) ◽  
pp. 14-19
Author(s):  
Dimitrios Bakas

Frailty syndrome is a geriatric syndrome characterized by increased vulnerability to stressors and for which there is no widely recognized and accepted clinical assessment scale. The two most widely used and commonly used frailty assessment indicators are the Frailty Phenotype and Frailty Index. The etiopathogenesis of frailty has complex and multifactorial etiology, with genetic, metabolic, environmental, socio-economic, nutritional, lifestyle, acute and chronic disease risk factors. Frailty is a risk factor for adverse outcomes in the health of older people. Physical exercise is the only intervention that has been confirmed by research to prevent the appearance of frailty in the elderly. The most effective preventive action is complete, thorough and comprehensive geriatric assessment by an interdisciplinary team.


2018 ◽  
Vol 2 (suppl_1) ◽  
pp. 718-718
Author(s):  
R Malhotra ◽  
C Chei ◽  
J Allen ◽  
A Chan ◽  
K Tan ◽  
...  

2019 ◽  
Vol 58 (2) ◽  
pp. 91-100 ◽  
Author(s):  
Eva Dolenc ◽  
Danica Rotar-Pavlič

Abstract Background The increase in the elderly population is causing changes and challenges that demand a comprehensive public health response. A specific characteristic of the elderly is their frailty. Today’s problems with identifying levels of frailty are being resolved by numerous tools in the form of frailty assessment scales. This systematic review establishes which frailty assessment scales for the elderly are being used and what their applicability in primary care is like in Slovenia and around the world. Methods Documents published after 2010 were searched for in the PubMed database using keywords and other specific criteria. Results A total of 177 search hits were obtained based on various search strings. The final analysis included 28 articles, of which three were systematic literature reviews. These three covered quantitative studies, mainly consisting of observational cross-sectional surveys or cohort studies. Three other studies featured non-systematic literature reviews. Quantitative studies (mainly cross-sectional surveys or cohort studies) prevailed among the remaining 22 articles. One study had a qualitative design (Delphi method). The main outcome measures observed by all studies were frailty assessment scales for the elderly, the majority of which were evaluated on a sample of the elderly. Conclusions None of the assessment scales examined are used as the gold standard for primary care. A variety of tools are being used in clinical practice to assess frailty in elderly patients, highlighting the need for standardization and guidelines. This requires evaluating the current assessment scales in terms of validity and reliability, and suitably improving them.


Author(s):  
J. Jacob ◽  
M.F.M. Ismail

Ultrastructural changes have been shown to occur in the urinary bladder epithelium (urothelium) during the life span of humans. With increasing age, the luminal surface becomes more flexible and develops simple microvilli-like processes. Furthermore, the specialised asymmetric structure of the luminal plasma membrane is relatively more prominent in the young than in the elderly. The nature of the changes at the luminal surface is now explored by lectin-mediated adsorption visualised by scanning electron microscopy (SEM).Samples of young adult (21-31 y old) and elderly (58-82 y old) urothelia were fixed in buffered 2% glutaraldehyde for 10 m and washed with phosphate buffered saline (PBS) containing Ca++ and Mg++ at room temperature. They were incubated overnight at 4°C in 0.1 M ammonium chloride in PBS to block any remaining aldehyde groups. The samples were then allowed to stand in PBS at 37°C for 2 h before incubation at 37°C for 30 m with lectins. The lectins used were concanavalin A (Con A), wheat germ agglutinin (WGA), phytohaemagglutinin (PHA) and pokeweed mitogen (PWM) at a concentration of 500 mg/ml in PBS at pH 7.A.


1988 ◽  
Vol 52 (9) ◽  
pp. 516-518 ◽  
Author(s):  
J Mann ◽  
TJ Bomberg ◽  
JM Holtzman ◽  
DB Berkey
Keyword(s):  

Author(s):  
Angel L. Ball ◽  
Adina S. Gray

Pharmacological intervention for depressive symptoms in institutionalized elderly is higher than the population average. Among the patients on such medications are those with a puzzling mix of symptoms, diagnosed as “dementia syndrome of depression,” formerly termed “pseudodementia”. Cognitive-communicative changes, potentially due to medications, complicate the diagnosis even further. This discussion paper reviews the history of the terminology of “pseudodementia,” and examines the pharmacology given as treatment for depressive symptoms in the elderly population that can affect cognition and communication. Clinicians can reduce the risk of misdiagnosis or inappropriate treatment by having an awareness of potential side effects, including decreased attention, memory, and reasoning capacities, particularly due to some anticholinergic medications. A team approach to care should include a cohesive effort directed at caution against over-medication, informed management of polypharmacology, enhancement of environmental/communication supports and quality of life, and recognizing the typical nature of some depressive signs in elderly institutionalized individuals.


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