Accurate Myocardial Pathology Segmentation with Residual U-Net

2020 ◽  
pp. 128-137
Author(s):  
Altunok Elif ◽  
Oksuz Ilkay
Keyword(s):  
Myocardial Pathology

Arachnodactyly Heart

PEDIATRICS ◽  
1959 ◽  
Vol 24 (4) ◽  
pp. 522-522
Author(s):  
S. G.
Keyword(s):  
Myocardial Hypertrophy ◽  
Coarctation Of The Aorta ◽  
Hereditary Disease ◽  
Pathologic Finding ◽  
Cardiovascular Pathology ◽  
Cardiac Malformations ◽  
Septal Defects ◽  
Aneurysm Formation ◽  
Cardiac Decompensation ◽  
Myocardial Pathology

Cardiovascular lesions are known to be frequently associated with arachnodactyly. The most common pathologic finding is cystic medionecrosis, particularly affecting the aorta, which often gives rise to aneurysm formation. Congenital cardiac malformations have also been described in patients with arachnodactyly; the more common lesions encountered are coarctation of the aorta and septal defects. From his experience at the Gronigen Clinic, Netherlands, the author reports another, but less frequently observed, finding of myocardial hypertrophy and fibrosis, in the absence of other cardiovascular pathology; this lesion leads eventually to cardiac decompensation and demise. The term "arachnodactyly heart" is proposed to designate the primary myocardial pathology in this hereditary disease.

Myocardial pathology segmentation of multi-modal cardiac MR images with a simple but efficient

2022 ◽  
Vol 71 ◽  
pp. 103174
Author(s):  
Weisheng Li ◽  
Linhong Wang ◽  
Feiyan Li ◽  
Sheng Qin ◽  
Bin Xiao
Keyword(s):  
Mr Images ◽  
Cardiac Mr ◽  
Myocardial Pathology

scholarly journals Diagnosis of myocardial infarction at autopsy: AECVP reappraisal in the light of the current clinical classification

2019 ◽  
Vol 476 (2) ◽  
pp. 179-194 ◽  
Author(s):  
Katarzyna Michaud ◽  
◽  
Cristina Basso ◽  
Giulia d’Amati ◽  
Carla Giordano ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Myocardial Injury ◽  
Coronary Occlusion ◽  
Diagnostic Methods ◽  
Myocardial Infarctions ◽  
Post Mortem ◽  
Acute Coronary Occlusion ◽  
Different Types ◽  
Third Person ◽  
Myocardial Pathology

Abstract Ischemic heart disease is one of the leading causes of morbidity and death worldwide. Consequently, myocardial infarctions are often encountered in clinical and forensic autopsies, and diagnosis can be challenging, especially in the absence of an acute coronary occlusion. Precise histopathological identification and timing of myocardial infarction in humans often remains uncertain while it can be of crucial importance, especially in a forensic setting when third person involvement or medical responsibilities are in question. A proper post-mortem diagnosis requires not only up-to-date knowledge of the ischemic coronary and myocardial pathology, but also a correct interpretation of such findings in relation to the clinical scenario of the deceased. For these reasons, it is important for pathologists to be familiar with the different clinically defined types of myocardial infarction and to discriminate myocardial infarction from other forms of myocardial injury. This article reviews present knowledge and post-mortem diagnostic methods, including post-mortem imaging, to reveal the different types of myocardial injury and the clinical-pathological correlations with currently defined types of myocardial infarction.

Hypertensive-diabetic cardiomyopathy in rats

1990 ◽  
Vol 258 (3) ◽  
pp. H793-H805 ◽  
Author(s):  
F. S. Fein ◽  
B. E. Zola ◽  
A. Malhotra ◽  
S. Cho ◽  
S. M. Factor ◽  
...  
Keyword(s):  
Action Potential ◽  
Right Ventricular ◽  
Action Potential Duration ◽  
Stimulus Frequency ◽  
Negative Inotropic Effect ◽  
Left Ventricular ◽  
Resting Membrane Potential ◽  
Contraction And Relaxation ◽  
And Control ◽  
Myocardial Pathology

Left ventricular papillary muscle function, transmembrane action potentials, myosin adenosinetriphosphatase (ATPase) and isoenzyme distribution, and myocardial pathology were studied in hypertensive (H), diabetic (D), hypertensive-diabetic (HD), and control (C) rats. There was approximately 50% relative left ventricular hypertrophy in H and HD rats. Relative lung and liver weights were greater in HD rats. Peak velocity of shortening tended to decrease progressively in H, D, and HD rats. The duration of contraction and relaxation was markedly prolonged in Ds and HDs. The length-developed tension relation was blunted in HDs. The negative inotropic effect of verapamil was similar in all groups. Resting membrane potential and amplitude were decreased in D and HD rats. Action potential duration was increased in H, D, and especially HD rats. The shortening of action potential duration with increased stimulus frequency was greater in H, D, and especially HD rats than in Cs. Left ventricular myosin ATPase and V1 isoenzyme content decreased progressively in H, D, and HD rats. Right ventricular V1 isoenzyme content was not affected in H rats but was markedly decreased in D and HD rats. Left (and right) ventricular pathology was unchanged in rats with diabetes but was increased in rats with hypertension. These data suggest that the combination of myocardial pathology (due to hypertension) and cellular dysfunction (caused mainly by diabetes) may result in cardiomyopathy and congestive heart failure in the HD rat.

scholarly journals Myocardial tissue characterisation using echocardiographic deformation imaging

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Mohammed A. Moharram ◽  
Regis R. Lamberts ◽  
Gillian Whalley ◽  
Michael J. A. Williams ◽  
Sean Coffey
Keyword(s):  
Current Knowledge ◽  
Imaging Modality ◽  
Imaging Techniques ◽  
Management Strategies ◽  
Cardiac Imaging Techniques ◽  
Attractive Alternative ◽  
Tissue Characterisation ◽  
Segmental Analysis ◽  
Tissue Characteristics ◽  
Myocardial Pathology

AbstractMyocardial pathology results in significant morbidity and mortality, whether due to primary cardiomyopathic processes or secondary to other conditions such as ischemic heart disease. Cardiac imaging techniques characterise the underlying tissue directly, by assessing a signal from the tissue itself, or indirectly, by inferring tissue characteristics from global or regional function. Cardiac magnetic resonance imaging is currently the most investigated imaging modality for tissue characterisation, but, due to its accessibility, advanced echocardiography represents an attractive alternative. Speckle tracking echocardiography (STE) is a reproducible technique used to assess myocardial deformation at both segmental and global levels. Since distinct myocardial pathologies affect deformation differently, information about the underlying tissue can be inferred by STE. In this review, the current available studies correlating STE deformation parameters with underlying tissue characteristics in humans are examined, with separate emphasis on global and segmental analysis. The current knowledge is placed in the context of integrated backscatter and the future of echocardiographic based tissue characterisation is discussed. The use of these imaging techniques to more precisely phenotype myocardial pathology more precisely will allow the design of translational cardiac research studies and, potentially, tailored management strategies.

Aldosterone and Myocardial Pathology

2019 ◽  
pp. 387-406 ◽  
Author(s):  
Alessandro Cannavo ◽  
Andrea Elia ◽  
Daniela Liccardo ◽  
Giuseppe Rengo ◽  
Walter J. Koch
Keyword(s):  
Myocardial Pathology

scholarly journals Dynamic pattern in the structural-functional parameters of the heart in children with myocardial pathology, taking into account morphological functional features of the right ventricle

2018 ◽  
pp. 32-36
Author(s):  
T. А. Holovko
Keyword(s):  
Left Ventricle ◽  
Right Ventricle ◽  
Children And Adolescents ◽  
Systolic Dysfunction ◽  
Structure And Function ◽  
Dynamic Pattern ◽  
Functional Features ◽  
The Right ◽  
And Function ◽  
Myocardial Pathology

The purpose of the study was to study the dynamics of changes in morphofunctional heart changes inchildren with non-inflammatory pathology of myocardium on the background of ongoing therapy. There were examined 115 patients (11–18 years old) with various heart diseases.The systolic dysfunction of the myocardium was diagnosedin 50 of them, and treatment was prescribed. In the dynamics, a year later, 40 patients were examined.  It has been established that in children and adolescents, along withpathogenetic and cardiometabolic therapy, in parallel with the improvement of the structure and function of the right ventricle of the heart, morphofunctional indicators ofthe left ventricle are improved.

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