scholarly journals Computing L(p, 1)-Labeling with Combined Parameters

2021 ◽  
pp. 208-220
Author(s):  
Tesshu Hanaka ◽  
Kazuma Kawai ◽  
Hirotaka Ono
Keyword(s):  
Combined Parameters

DNA Content of Normal and Neoplastic Urothelial Cells

1980 ◽  
Vol 66 (4) ◽  
pp. 445-458 ◽  
Author(s):  
Mathilde E. Boon
Keyword(s):  
Dna Content ◽  
Cell Populations ◽  
Malignant Cells ◽  
Urothelial Cells ◽  
Chromatin Pattern ◽  
Normal Bladder ◽  
Well Differentiated ◽  
Dna Measurements ◽  
Combined Parameters ◽  
Umbrella Cells

In search for suitable parameters to detect neoplastic urothelial cells in Acriflavine-Feulgen-SITS stained specimen we compared the cytofluorometric DNA content with the morphology of normal urothelial cells (bladder scrapings) and neoplastic urothelial cells from grade 1, 2, 3 and 4 tumors. An individual normal urothelial cell could not be distinguished from a grade 1 tumor cell, neither morphologically nor fluorometrically. However, the shape of the histograms of DNA measurements of the cell populations of respectively normal bladder scrapings and grade 1 tumors differs. It is postulated that also morphometry of these cell populations may be of some aid to distinguish well-differentiated neoplastic cells from normal urothelial cells. Seventy-one percent of the morphologically malignant cells in the grade 2, 3 and 4 tumor samples could be identified by applying the combined parameters: high DNA content (> 5 C) and nuclear-cytoplasmic ratio (> 0.5) and all grade 2, 3 and 4 tumor samples contained cells which were objectively classified as malignant. Using the same parameters morphologically malignant cells could be distinguished from normal, polyploid umbrella cells, thus these malignant cells are detectable objectively without using chromatin pattern as parameter.

The Axisymmetric Deformation of Linearly and Nonlinearly Elastic Spinning Tubes Under End Thrusts and Torques

1998 ◽  
Vol 65 (1) ◽  
pp. 99-106
Author(s):  
T. J. McDevitt ◽  
J. G. Simmonds
Keyword(s):  
Anisotropic Material ◽  
Large Strain ◽  
Axisymmetric Deformation ◽  
Large Strains ◽  
Shells Of Revolution ◽  
Large Rotation ◽  
Elastic Tubes ◽  
Axisymmetric Bending ◽  
Combined Parameters ◽  
Nonlinearly Elastic

We consider the steady-state deformations of elastic tubes spinning steadily and attached in various ways to rigid end plates to which end thrusts and torques are applied. We assume that the tubes are made of homogeneous linearly or nonlinearly anisotropic material and use Simmonds” (1996) simplified dynamic displacement-rotation equations for shells of revolution undergoing large-strain large-rotation axisymmetric bending and torsion. To exploit analytical methods, we confine attention to the nonlinear theory of membranes undergoing small or large strains and the theory of strongly anisotropic tubes suffering small strains. Of particular interest are the boundary layers that appear at each end of the tube, their membrane and bending components, and the penetration of these layers into the tube which, for certain anisotropic materials, may be considerably different from isotropic materials. Remarkably, we find that the behavior of a tube made of a linearly elastic, anisotropic material (having nine elastic parameters) can be described, to a first approximation, by just two combined parameters. The results of the present paper lay the necessary groundwork for a subsequent analysis of the whirling of spinning elastic tubes under end thrusts and torques.

Arginase as a Useful Factor for the Diagnosis of Colorectal Cancer Liver Metastases

2006 ◽  
Vol 21 (1) ◽  
pp. 40-44 ◽  
Author(s):  
M. Mielczarek ◽  
A. Chrzanowska ◽  
D. Ścibior ◽  
A. Skwarek ◽  
F. Ashamiss ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastases ◽  
Blood Donors ◽  
Tumor Resection ◽  
Gastrointestinal Diseases ◽  
Arginase Activity ◽  
Control Group ◽  
Colorectal Cancer Liver Metastases ◽  
Combined Parameters

The present work is a continuation of studies on arginase as a marker in the diagnosis of colorectal cancer liver metastases (CRCLM). The purpose of the study was the evaluation of the arginase test in comparison with other colorectal cancer tests such as CEA, CA 19-9 and biochemical markers of liver function such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT). The studies were conducted on blood serum from 85 patients with CRCLM obtained one to two days before tumor resection. The control group comprised 140 healthy blood donors and 81 patients with various non-malignant gastrointestinal diseases. Raised arginase activity was observed in serum of 85% of CRCLM patients, whereas elevated levels of CEA and CA 19-9 were found in 63% and 42% of patients, respectively. The combination of CEA or CA 19-9 with the arginase assay improved their sensitivity, but the sensitivity of the combined parameters was not higher than that of the arginase test itself. AST and ALT activities were increased in about 30% of CRCLM patients. The specificity of the arginase test calculated for 221 control subjects was 76%. It can thus be concluded that the determination of serum arginase activity can be helpful in the diagnosis of patients with colorectal cancer liver metastases.

scholarly journals Point Shear Wave Elastography of the Spleen in Predicting the Presence of Esophageal Varices in Cirrhosis: Liver Stiffness vs. Spleen Stiffness

2019 ◽  
Vol 36 (2) ◽  
pp. 95-101
Author(s):  
Nadella Sindhu ◽  
Prakashini Koteshwar ◽  
Shiran Shetty
Keyword(s):  
Esophageal Varices ◽  
Statistical Tests ◽  
Characteristic Curve ◽  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Significant Difference ◽  
Spleen Stiffness ◽  
Cirrhotic Patients ◽  
The Difference ◽  
Combined Parameters

Objective: To determine the diagnostic ability of the spleen and liver stiffness in predicting the presence of esophageal varices (EVs). Methods: A sample of cirrhotic patients, diagnosed with sonography, was recruited. The cohorts’ liver stiffness (LS) and spleen stiffness (SS) were measured with the Philips’ Elast PQ technique. Platelet count and spleen size were also documented. The endoscopic report was used as the diagnostic gold standard. Singular and combined parameters were assessed to determine the presence of EV using an independent variable t test, area under the receiver operating characteristic curve, and multilogistic regression analysis statistical tests. Results: In predicting the presence of EV, there was a statistically significant difference in means of SS (2.13 ± 0.69 m/s vs. 3.23 ± 1.32 m/s) and LS (2.33 ± 1.20 m/s vs. 3.05 ± 1.4 m/s), as well as discriminating between groups of patients, with and without EV. The ability to diagnostically classify EV with SS and LS was fair while the remaining parameters were deemed poor, using a SS cutoff value of 1.99 m/s. Conclusion: Despite the difference in means, none of the assessed parameters demonstrated a better classification ability than endoscopy. LS and SS were equal in the prediction of EV in these patients. The LS estimate of fibrosis would have grossly predicted the presence of varices. However, the addition of SS, for the estimation of varices, provided no significant benefit.

Numerical Simulation on Mass Transport in a Microchannel Bioreactor for Co-culture Applications

2006 ◽  
Vol 129 (3) ◽  
pp. 365-373 ◽  
Author(s):  
Yan Zeng ◽  
Thong-See Lee ◽  
Peng Yu ◽  
Hong-Tong Low
Keyword(s):  
Mass Transport ◽  
Three Dimensional ◽  
Culture Cell ◽  
Inlet Concentration ◽  
Single Culture ◽  
Different Types ◽  
Flux Parameter ◽  
Combined Parameters ◽  
Axial Concentration ◽  
Cell Base

Microchannel bioreactors have applications for manipulating and investigating the fluid microenvironment on cell growth and functions in either single culture or co-culture. This study considers two different types of cells distributed randomly as a co-culture at the base of a microchannel bioreactor: absorption cells, which only consume species based on the Michaelis-Menten process, and release cells, which secrete species, assuming zeroth order reaction, to support the absorption cells. The species concentrations at the co-culture cell base are computed from a three-dimensional numerical flow-model incorporating mass transport. Combined dimensionless parameters are proposed for the co-culture system, developed from a simplified analysis under the condition of decreasing axial-concentration. The numerical results of species concentration at the co-culture cell-base are approximately correlated by the combined parameters under the condition of positive flux-parameter. Based on the correlated results, the critical value of the inlet concentration is determined, which depends on the effective microchannel length. For the flow to develop to the critical inlet concentration, an upstream length consisting only of release cells is needed; this upstream length is determined from an analytical solution. The generalized results may find applications in analyzing the mass transport requirements in a co-culture microchannel bioreactor.

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