Bone Quantity

2021 ◽  
pp. 25-28
Author(s):  
Sina Ayati ◽  
Shohreh Ghasemi
Keyword(s):  
Bone Quantity

Diabetes and osteoporosis

2011 ◽  
Vol 152 (29) ◽  
pp. 1161-1166 ◽  
Author(s):  
Zsuzsanna Valkusz
Keyword(s):  
Vitamin D ◽  
Type 1 Diabetes ◽  
Bone Mass ◽  
Fragility Fractures ◽  
Vitamin D Supplementation ◽  
Bone Collagen ◽  
Skeletal Changes ◽  
Glucagon Like Peptide 1 ◽  
Bone Quantity

Over the last decades a considerable amount of data has accumulated to indicate that metabolic and endocrine alterations of diabetes affect bone quantity and quality. These skeletal changes may increase the risk of bone fracture. There is strong evidence that in type 1 diabetes the decreased bone mass, lack of insulin and insulin-like growth factor-1, dysregulation of adipokines, and increased levels of proinflammatory cytokines are in the background of fragility fractures. In type 2 diabetes hyperinsulinemia, insulin resistance and increased body weight may result in an increase of bone mass; however, accumulation of advanced glycation end products within the bone collagen driven by glucotoxicity may increase the cortical porosity. There is a higher incidence of falls resulting from diabetes-related co-morbidities such as diabetic retinopathy, peripheral neuropathy, hypoglycemic episodes and sometimes from the medications. Vitamin D deficiency has special impact on glucose metabolism and the prevalence of diabetes. Vitamin D supplementation in childhood can decrease incidence of type 1 diabetes by 80%. The effect of thiazolidinediones, glucagon-like peptide-1 agonists and metformin, agents for treatment of diabetes open a new connection between bone, carbohydrate and fat metabolism. Orv. Hetil., 2011, 152, 1161–1166.

scholarly journals Comparison of Piezosurgery and Conventional Rotary Instruments for Removal of Impacted Mandibular Third Molars: A Randomized Controlled Clinical and Radiographic Trial

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Hani Arakji ◽  
Mohamed Shokry ◽  
Nayer Aboelsaad
Keyword(s):  
Statistical Significance ◽  
Third Molar ◽  
Test Site ◽  
Surgical Removal ◽  
Third Molars ◽  
Randomized Controlled ◽  
Surgical Extraction ◽  
Impacted Mandibular Third Molars ◽  
Mandibular Third Molars ◽  
Bone Quantity

The purpose of this study was to test the effect of the surgical removal of impacted mandibular third molars using piezosurgery versus the conventional surgical technique on postoperative sequelae and bone healing.Material and Methods.This study was carried out as a randomized controlled clinical trial: split mouth design. Twenty patients with bilateral mandibular third molar mesioangular impaction class II position B indicated for surgical extraction were treated randomly using either the piezosurgery or the conventional bur technique on each site. Duration of the procedure, postoperative edema, trismus, pain, healing, and bone density and quantity were evaluated up to 6 months postoperatively.Results.Test and control sites were compared using pairedt-test. There was statistical significance in reduction of pain and swelling in test sites, where the time of the procedure was statistically increased in test site. For bone quantity and quality, statistical difference was found where test site showed better results.Conclusion.Piezosurgery technique improves quality of patient’s life in form of decrease of postoperative pain, trismus, and swelling. Furthermore, it enhances bone quality within the extraction socket and bone quantity along the distal aspect of the mandibular second molar.

scholarly journals Hematopoietic Wnts Modulate Endochondral Ossification During Fracture Healing

2021 ◽  
Vol 12 ◽  
Author(s):  
Kenon Chua ◽  
Victor K. Lee ◽  
Cheri Chan ◽  
Andy Yew ◽  
Eric Yeo ◽  
...  
Keyword(s):  
Fracture Healing ◽  
Knockout Mice ◽  
Bone Repair ◽  
Critical Role ◽  
Computer Assisted ◽  
Stress Tests ◽  
Fracture Callus ◽  
Normal Bone ◽  
Musculoskeletal Development ◽  
Bone Quantity

Wnt signaling plays a critical role in bone formation, homeostasis, and injury repair. Multiple cell types in bone have been proposed to produce the Wnts required for these processes. The specific role of Wnts produced from cells of hematopoietic origin has not been previously characterized. Here, we examined if hematopoietic Wnts play a role in physiological musculoskeletal development and in fracture healing. Wnt secretion from hematopoietic cells was blocked by genetic knockout of the essential Wnt modifying enzyme PORCN, achieved by crossing Vav-Cre transgenic mice with Porcnflox mice. Knockout mice were compared with their wild-type littermates for musculoskeletal development including bone quantity and quality at maturation. Fracture healing including callus quality and quantity was assessed in a diaphyseal fracture model using quantitative micro computer-assisted tomographic scans, histological analysis, as well as biomechanical torsional and 4-point bending stress tests. The hematopoietic Porcn knockout mice had normal musculoskeletal development, with normal bone quantity and quality on micro-CT scans of the vertebrae. They also had normal gross skeletal dimensions and normal bone strength. Hematopoietic Wnt depletion in the healing fracture resulted in fewer osteoclasts in the fracture callus, with a resultant delay in callus remodeling. All calluses eventually progressed to full maturation. Hematopoietic Wnts, while not essential, modulate osteoclast numbers during fracture healing. These osteoclasts participate in callus maturation and remodeling. This demonstrates the importance of diverse Wnt sources in bone repair.

Influence of Bisphosphonates on Implant Failure Rates and Characteristics of Postmenopausal Woman Mandibular Jawbone

2017 ◽  
Vol 43 (5) ◽  
pp. 345-349 ◽  
Author(s):  
Naoko Yajima ◽  
Motohiro Munakata ◽  
Kei Fuchigami ◽  
Minoru Sanda ◽  
Shohei Kasugai
Keyword(s):  
Computed Tomography ◽  
Dental Implants ◽  
Cortical Thickness ◽  
Quantitative Computed Tomography ◽  
Implant Failure ◽  
Mineral Density ◽  
Mandibular Bone ◽  
Alternate Therapy ◽  
Group 2 ◽  
Bone Quantity

Rehabilitation of oral function using dental implants is clinically effective and highly predictable. Both bone quantity and quality at the implant site affect the success of the procedure. However, the effect of bisphosphonate (BP) use on mandibular bone quality has not been well documented. The purpose of this retrospective cohort study was to evaluate the bone mineral density (BMD) and cortical thickness of the mandible, as well as the influence of BP use on early implant failure. Twenty-five female patients (≥60 years of age) were selected from among 93 candidates with partially edentulous posterior mandibles. Eleven patients had received BP therapy using alendronate (BP group), and 14 patients had received alternate therapy (non-BP group). Cortical and trabecular BMD was measured using quantitative computed tomography. Cortical thickness was measured using computed tomography. The BMDs and cortical thicknesses of the two groups were compared. The results were as follows: (1) Cortical BMD was significantly higher in the BP group, (2) trabecular BMD was not affected by BP use, and (3) Cortical thickness was affected by the duration of BP use. These results indicate that BP use affects the quality and quantity of the cortical bone in the partially edentulous posterior mandible of patients with osteoporosis, which should be considered prior to treatment with dental implants in patients taking BPs.

Bone quantity and quality in Brazilian female schoolchildren and adolescents

2009 ◽  
Vol 27 (4) ◽  
pp. 507-512 ◽  
Author(s):  
Keila Donassolo Santos ◽  
Edio Luiz Petroski ◽  
Roberto Regis Ribeiro ◽  
Gil Guerra-Junior
Keyword(s):  
Bone Quantity

scholarly journals Strategic Implants under Existing Partial Removable Dentures, Why, How Many, and Which Type?

2021 ◽  
Author(s):  
Ahmad Al Jaghsi
Keyword(s):  
Bone Resorption ◽  
Health Related Quality ◽  
Chewing Ability ◽  
Removable Denture ◽  
Related Quality ◽  
Health Related ◽  
Implant Therapy ◽  
Bone Quantity ◽  
Improve Patient

Inserting strategic implants under existing removable partial dentures requires a comprehensive understanding of removable prosthodontic basics and possible designs, as well as a thorough understanding of implant therapy. Prior to the widespread adoption of implants as standard prosthetic therapy, remaining roots were preserved and used to minimize bone resorption under the removable denture. Root-supported overdentures become less common after the overwhelming clinical studies that emphasize dental implants’ reliability and high success and survival rate. Fixed prostheses cannot be used to treat a severely decreased dentition unless a significant number of implants can be inserted, sufficient bone quantity and quality are available, and the patients can afford the treatment. On the other hand, using strategic implants under existing RPD upgrades the design to a more favorable support type. It improves patient satisfaction with the RPD in speaking, chewing, retention, stability, and RPD support. This improvement could be reached earlier if the patient received immediate loading. Strategic implants can also improve chewing ability, stabilize the occlusion, increase bite force and improve patient oral health-related quality of life. Moreover, better distribution of occlusal forces that may reduce bone resorption may be gained. Furthermore, strategic implants can improve comfort, confidence, and esthetics by reducing the RPD size and removing the retainers from the esthetic zone.

Mechanisms of exercise effects on bone quantity and quality

2020 ◽  
pp. 1759-1784 ◽  
Author(s):  
Vihitaben S. Patel ◽  
Stefan Judex ◽  
Janet Rubin ◽  
Clinton T. Rubin
Keyword(s):  
Bone Quantity

scholarly journals Relationship between the changes over time of bone mass and muscle health in children and adults: a systematic review and meta-analysis

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Médéa Locquet ◽  
Charlotte Beaudart ◽  
Nancy Durieux ◽  
Jean-Yves Reginster ◽  
Olivier Bruyère
Keyword(s):  
Systematic Review ◽  
Lean Mass ◽  
Meta Analysis ◽  
Mineral Density ◽  
Cross Sectional ◽  
Ovid Medline ◽  
Parallel Change ◽  
Hip Bmd ◽  
Muscle Health ◽  
Bone Quantity

Abstract Background Various cross-sectional studies provide an abundance of evidence that shows a relationship between bone quantity and muscle health. However, one question remains, less-often studied: is their development - or decline – associated? The aim of the research was to conduct a systematic review and meta-analysis to summarize the studies exploring the association between changes in bone mineral density (BMD) and changes in muscle parameters (registration CRD42018093813). Methods We searched for prospective studies, both in children and adults, by consulting electronic databases (Ovid-MEDLINE, Ovid-AMED, Scopus). Each review steps were performed by two independent reviewers. For outcomes reported by less of 3 studies, we synthetized the results narratively. In other cases, a meta-analysis was performed, giving an overall r coefficient and its 95% confidence interval (CI). Results Fifteen papers were included. In connection with the change of BMD, 10 studies concerned the parallel change of lean mass, 4 were about grip strength, and 1 was about physical performance. Children were the population of interest for 5 studies, while the aging population was the focus of the other studies. The correlation between hip BMD and lean mass was significant, with an overall coefficient r = 0.37 (95% CI 0.23–0.49). High heterogeneity was observed between studies but the length of follow-up, sex and study quality did not seem to significantly influence results. The systematic review allowed some other highlights: a significant link between changes in BMD and changes in muscle strength was observed (p-value < 0.05 in the 4 studies), in addition to changes in performance (1 study, r = 0.21, p-value = 0.004). Conclusion Despite the heterogeneity between studies, we highlighted a significant association between the change of BMD and the change of various muscle parameters. Future studies should investigate preventive and therapeutic strategies that are based on a single entity: the ‘muscle-bone unit’.

Sign in / Sign up

Export Citation Format

Share Document