POCUS Application in Neurocritical Care Patients: Transcranial Doppler (TCD/TCCS) as a Part of POCUS, from the Brain Ultrasound to Monitoring the Systemic Complications

2021 ◽  
pp. 975-997
Author(s):  
Raffaele Aspide ◽  
Chiara Robba ◽  
Federico Bilotta
2021 ◽  
Vol 9 (6) ◽  
Author(s):  
Alejandro Cardozo

Bedside ultrasound allows diagnostic, therapeutic and monitoring approaches in critically ill patients. Currently ultrasound enables to perform a scan almost of all body regions in both adult and pediatric populations. Head and especially central nervous system, have traditionally been excluded, based on the idea that access to the brain is not possible given the limitation of the skull, Therefore in adults, the main ultrasound applications in central nervous system assessment have been limited to the transcranial Doppler and the measurement of the optic nerve sheath as a subrogate finding of intracranial hypertension. Nonetheless, through the temporal bone window it is possible to visualize the midline (third ventricle), nuclei basal ganglia, the mesencephalon and the lateral ventricles: the basic structures for the brain ultrasound Although the Gold standard for the initial assessment of many neurological pathologies in the emergency department is computed tomography; the ultrasonography allows an approximation to the midline shift and acute bleeding, combined with transcranial doppler some hemodynamics estimations can be acceded, this allow the diagnosis or follow-up of increased intracranial pressure which could favor pharmacological treatments and follow the therapeutic effect. In this review, basic B mode neurosonology for the emergency physician is explored and future directions discussed.


2019 ◽  
Vol 06 (03) ◽  
pp. 275-283
Author(s):  
Siddharth Chavali ◽  
Manjari Tripathi ◽  
Vanitha Rajagopalan

AbstractFever occurs commonly in patients admitted to the neurocritical care unit. An increase in the body temperature is known to have deleterious effects on patients with acute nervous system injury and in most cases is associated with an increase in mortality and morbidity of these patients. There are multiple causes of fever in these patients. Due to the potentially devastating effects of fever in patients with cerebral diseases, it warrants treatment in every case. In all patients with acute cerebral damage, treatment of fever and maintenance of euthermia is important to obtain a better functional recovery and to limit any further secondary insult to the brain. This review highlights the etiology and pathophysiology of fever in neurocritical care unit patients, the effects on various organ systems and associated systemic complications, and the evaluation and different therapeutic options available for the management of fever in this patient subset.


2017 ◽  
Vol 96 (4) ◽  
pp. 720-730 ◽  
Author(s):  
Chiara Robba ◽  
Danilo Cardim ◽  
Mypinder Sekhon ◽  
Karol Budohoski ◽  
Marek Czosnyka

2017 ◽  
Vol 6 (3) ◽  
pp. 195-204
Author(s):  
Ida Bagus Krisna J. Sutawan ◽  
◽  
Siti Chasnak Saleh ◽  
Tatang Bisri ◽  
◽  
...  

2017 ◽  
Vol 04 (04) ◽  
pp. S49-S55
Author(s):  
Michael Souter

AbstractSubarachnoid haemorrhage (SAH) is a consistent presentation of haemorrhagic stroke of significance to clinicians in neurocritical care, inducing consequent effects on non-neurological systems, while at the same time, rendering the brain vulnerable to secondary physiological insult modifying neurological outcome, despite control of the original point of haemorrhage. Coordinated treatment depends on comprehensive evaluation of both cerebral and systemic physiology, identifying and treating impaired function. The presence of a dedicated neurocritical care team can benefit outcome. Protocols of care have evolved to meet evidence-based challenges, discarding potentially deleterious components of hypervolaemia and haemodilution, while maintaining pressure-guided perfusion. Treatment targets have also evolved with a shift in focus away from SAH-associated vasospasm, towards actual ischaemic outcome – illustrated by lack of effectiveness of pharmaceutical treatments of vasospasm. Clinicians must consequently review pathophysiological mechanisms of injury and devise new treatment opportunities.


2019 ◽  
Vol 8 (3) ◽  
pp. 162
Author(s):  
Aloka Samantaray ◽  
Hemanth Natham ◽  
Mukkara Madhusudan ◽  
Hemalatha Pasupuleti

Author(s):  
Eelco F.M. Wijdicks ◽  
Sarah L. Clark

Drugs are used to treat, salvage, and protect the brain. This book provides information on how to prescribe and monitor the drugs most frequently used in the emergency department and the neurosciences critical care unit. Each drug is discussed in great detail to allow for its efficient use and to allow the recognition of drug-related problems. The book explains how these drugs work and what the body does with the drug in the acutely ill neurologic patient. It provides guidance on how these drugs are best administered and revisits how we can most effectively practice medication reconciliation. This manual has multiple useful concise tables and graphs summarizing over 150 drugs.


Author(s):  
Patrick M. Kochanek ◽  
Rachel P. Berger

A variety of biomarkers of brain injury are being developed in neurocritical care to study secondary injury pathways or aid in diagnostic, prognostic, and/or theragnostic applications. This chapter focuses largely on brain injury biomarkers that can be detected in serum or cerebrospinal fluid samples from patients with acute critical brain injury of various causes. Much of the work has been carried using biomarkers of proteins that are relatively unique to the brain, and that reflect damage to important cellular constituents such as neurons, astroycytes, or axons. Novel approaches that employ a panel of markers or novel analytic methods such as trajectory analysis may optimize the utility of these biomarkers in clinical practice. We anticipate that there will soon be one or more protein biomarkers of brain injury available for clinical use.


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