Seeking Support from Multiple Developers: Assessing Optimal Structure, Content, Antecedents, and Outcomes of Developmental Networks

Author(s):  
Rajashi Ghosh ◽  
Wendy Murphy ◽  
Rick Cotton ◽  
Kathy E. Kram
2015 ◽  
Vol 2015 (3) ◽  
pp. 13-16 ◽  
Author(s):  
M.M. Makortetskiy ◽  
◽  
M.O. Perov ◽  
I.Yu. Novitsky ◽  
◽  
...  

2020 ◽  
Vol 12 ◽  
Author(s):  
Alexandra Atyaksheva ◽  
Yermek Sarsikeyev ◽  
Anastasia Atyaksheva ◽  
Olga Galtseva ◽  
Alexander Rogachev

Aims:: The main goals of this research are exploration of energy-efficient building materials when replacing natural materials with industrial waste and development of the theory and practice of obtaining light and ultra-light gravel materials based on mineral binders and waste dump ash and slag mixtures of hydraulic removal. Background.: Experimental data on the conditions of formation of gravel materials containing hollow aluminum and silica microsphere with opportunity of receipt of optimum structure and properties depending on humidity with the using of various binders are presented in this article. This article dwells on the scientific study of opportunity physical-mechanical properties of composite materials optimization are considered. Objective.: Composite material contains hollow aluminum and silica microsphere. Method.: The study is based on the application of the method of separation of power and heat engineering functions. The method is based on the use of the factor structure optimality, which takes into account the primary and secondary stress fields of the structural gravel material. This indicates the possibility of obtaining gravel material with the most uniform distribution of nano - and microparticles in the gravel material and the formation of stable matrices with minimization of stress concentrations. Experiments show that the thickness of the cement shell, which performs power functions, is directly related to the size of the raw granules. At the same time, the thickness of the cement crust, regardless of the type of binder, with increasing moisture content has a higher rate of formation for granules of larger diameter. Results.: The conditions for the formation of gravel composite materials containing a hollow aluminosilicate microsphere are studied. The optimal structure and properties of the gravel composite material were obtained. The dependence of the strength function on humidity and the type of binder has been investigated. The optimal size and shape of binary form of gravel material containing a hollow aluminosilicate microsphere with a minimum thickness of a cement shell and a maximum strength function was obtained. Conclusion.: Received structure allows to separate power and heat engineering functions in material and to minimize the content of the excited environment centers.


2021 ◽  
Vol 7 ◽  
pp. 2057-2067
Author(s):  
Yi-Peng Xu ◽  
Ping Ouyang ◽  
Si-Ming Xing ◽  
Lu-Yu Qi ◽  
Majid khayatnezhad ◽  
...  

Energies ◽  
2021 ◽  
Vol 14 (15) ◽  
pp. 4417
Author(s):  
Tingting Xu ◽  
Hongxia Zhao ◽  
Miao Wang ◽  
Jianhui Qi

Printed circuit heat exchangers (PCHEs) have the characteristics of high temperature and high pressure resistance, as well as compact structure, so they are widely used in the supercritical carbon dioxide (S-CO2) Brayton cycle. In order to fully study the heat transfer process of the Z-type PCHE, a numerical model of traditional Z-type PCHE was established and the accuracy of the model was verified. On this basis, a new type of spiral PCHE (S-ZPCHE) is proposed in this paper. The segmental design method was used to compare the pressure changes under 5 different spiral angles, and it was found that increasing the spiral angle θ of the spiral structure will reduce the pressure drop of the fluid. The effects of different spiral angles on the thermal-hydraulic performance of S-ZPCHE were compared. The results show that the pressure loss of fluid is greatly reduced, while the heat transfer performance is slightly reduced, and it was concluded that the spiral angle of 20° is optimal. The local fluid flow states of the original structure and the optimal structure were compared to analyze the reason for the pressure drop reduction effect of the optimal structure. Finally, the performance of the optimal structure was analyzed under variable working conditions. The results show that the effect of reducing pressure loss of the new S-ZPCHE is more obvious in the low Reynolds number region.


2021 ◽  
Vol 559 ◽  
pp. 120686
Author(s):  
Xiaomei Wang ◽  
Jingxiang Su ◽  
Yingying Wang ◽  
Chenfeng Yang ◽  
Shixun Dai ◽  
...  

Genes ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 14
Author(s):  
Ronny Lorenz ◽  
Peter F. Stadler

The accuracy of RNA secondary structure prediction decreases with the span of a base pair, i.e., the number of nucleotides that it encloses. The dynamic programming algorithms for RNA folding can be easily specialized in order to consider only base pairs with a limited span L, reducing the memory requirements to O(nL), and further to O(n) by interleaving backtracking. However, the latter is an approximation that precludes the retrieval of the globally optimal structure. So far, the ViennaRNA package therefore does not provide a tool for computing optimal, span-restricted minimum energy structure. Here, we report on an efficient backtracking algorithm that reconstructs the globally optimal structure from the locally optimal fragments that are produced by the interleaved backtracking implemented in RNALfold. An implementation is integrated into the ViennaRNA package. The forward and the backtracking recursions of RNALfold are both easily constrained to structural components with a sufficiently negative z-scores. This provides a convenient method in order to identify hyper-stable structural elements. A screen of the C. elegans genome shows that such features are more abundant in real genomic sequences when compared to a di-nucleotide shuffled background model.


2021 ◽  
Vol 7 (8) ◽  
pp. 624
Author(s):  
Ulises Carrasco-Navarro ◽  
Jesús Aguirre

Reactive oxygen species (ROS) regulate several aspects of cell physiology in filamentous fungi including the antioxidant response and development. However, little is known about the signaling pathways involved in these processes. Here, we report Aspergillus nidulans global phosphoproteome during mycelial growth and show that under these conditions, H2O2 induces major changes in protein phosphorylation. Among the 1964 phosphoproteins we identified, H2O2 induced the phosphorylation of 131 proteins at one or more sites as well as the dephosphorylation of a larger set of proteins. A detailed analysis of these phosphoproteins shows that H2O2 affected the phosphorylation of critical regulatory nodes of phosphoinositide, MAPK, and TOR signaling as well as the phosphorylation of multiple proteins involved in the regulation of gene expression, primary and secondary metabolism, and development. Our results provide a novel and extensive protein phosphorylation landscape in A. nidulans, indicating that H2O2 induces a shift in general metabolism from anabolic to catabolic, and the activation of multiple stress survival pathways. Our results expand the significance of H2O2 in eukaryotic cell signaling.


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