Inductive Machine Learning and Feature Selection for Knowledge Extraction from Medical Data: Detection of Breast Lesions in MRI

2021 ◽  
pp. 123-164
Author(s):  
Evangelos Karampotsis ◽  
Evangelia Panourgias ◽  
Georgios Dounias
2015 ◽  
Vol 8 (7) ◽  
pp. 5419-5435 ◽  
Author(s):  
W. Paja ◽  
M. Wrzesień ◽  
R. Niemiec ◽  
W. R. Rudnicki

Abstract. The climate models are extremely complex pieces of software. They reflect best knowledge on physical components of the climate, nevertheless, they contain several parameters, which are too weakly constrained by observations, and can potentially lead to a crash of simulation. Recently a study by Lucas et al. (2013) has shown that machine learning methods can be used for predicting which combinations of parameters can lead to crash of simulation, and hence which processes described by these parameters need refined analyses. In the current study we reanalyse the dataset used in this research using different methodology. We confirm the main conclusion of the original study concerning suitability of machine learning for prediction of crashes. We show, that only three of the eight parameters indicated in the original study as relevant for prediction of the crash are indeed strongly relevant, three other are relevant but redundant, and two are not relevant at all. We also show that the variance due to split of data between training and validation sets has large influence both on accuracy of predictions and relative importance of variables, hence only cross-validated approach can deliver robust prediction of performance and relevance of variables.


Author(s):  
M. Vidyasagar

The objectives of this Perspective paper are to review some recent advances in sparse feature selection for regression and classification, as well as compressed sensing, and to discuss how these might be used to develop tools to advance personalized cancer therapy. As an illustration of the possibilities, a new algorithm for sparse regression is presented and is applied to predict the time to tumour recurrence in ovarian cancer. A new algorithm for sparse feature selection in classification problems is presented, and its validation in endometrial cancer is briefly discussed. Some open problems are also presented.


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