Lesions of the Urinary Tract and Renal Sinus

Author(s):  
Li-Jen Wang
Keyword(s):  
2012 ◽  
Vol 136 (8) ◽  
pp. 907-910 ◽  
Author(s):  
Allison Young ◽  
Lakshmi P. Kunju

We report the case of a high-grade carcinoma involving the kidney in a young male with renal vein thrombosis and review the differential diagnosis and immunohistochemical workup. High-grade neoplasms involving the renal sinus include collecting duct carcinomas (CDCs), renal medullary carcinomas (RMCs), invasive high-grade urothelial carcinoma (UC) of the upper urinary tract, clear cell renal cell carcinoma, and type 2 papillary renal cell carcinoma. Distinguishing UC from CDC and RMC is problematic in small biopsy samples. The diagnosis of CDC (a rare, aggressive subtype of renal cell carcinoma) is challenging and requires the exclusion of UC. Renal medullary carcinoma is characterized by an appropriate clinical setting and consistent loss of nuclear expression of integrase interactor 1 (INI-1). A panel consisting of p63, paired box gene 8 (PAX8), and INI-1 is most optimal in distinguishing UC from CDC and RMC. A subset of urothelial carcinoma of upper urinary tract may be positive with PAX8.


1999 ◽  
Vol 123 (7) ◽  
pp. 631-634 ◽  
Author(s):  
Mitual B. Amin ◽  
Satish K. Tickoo ◽  
Daniel Schultz ◽  
Mahul B. Amin

Abstract Extra-adrenal myelolipomas are rare; approximately 36 cases have been reported to date. We document a case of myelolipoma presenting as a localized mass in the renal sinus of a 66-year-old man. The chief clinical and radiologic differential diagnostic considerations in this case included a malignant renal tumor arising in the hilum. The patient was being investigated for recurrent urinary tract infections and vague abdominal pains. Histologically, the lesion showed features characteristic of a myelolipoma. There was also marked chronic inflammation in and around the mass. The uneventful follow-up of 62 months is in keeping with the benign nature of this lesion. This report expands the possibilities of the differential diagnoses of renal hilar neoplasms, particularly in view of the increased use of imaging techniques that are bound to detect many incidental lesions in this region. (Arch Pathol Lab Med.1999;123:631–634)


JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 193-194
Author(s):  
E. N. Cook

2007 ◽  
Vol 177 (4S) ◽  
pp. 136-136
Author(s):  
Marco Roscigno ◽  
Cesare Cozzarini ◽  
Roberto Bertini ◽  
Vincenzo Scattoni ◽  
Alessandra Pastal ◽  
...  

2007 ◽  
Vol 177 (4S) ◽  
pp. 135-135
Author(s):  
Junya Furukawa ◽  
Hideaki Miyake ◽  
Kazushi Tanaka ◽  
Atsushi Takenaka ◽  
Isao Hara ◽  
...  

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