Automatic Segmentation of the Spinal Cord Using Continuous Max Flow with Cross-sectional Similarity Prior and Tubularity Features

2015 ◽  
pp. 107-118 ◽  
Author(s):  
Simon Pezold ◽  
Ketut Fundana ◽  
Michael Amann ◽  
Michaela Andelova ◽  
Armanda Pfister ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Automatic Segmentation ◽  
Cross Sectional

scholarly journals Neurophysiological changes of brain and spinal cord in individuals with patellofemoral pain: a systematic review and meta-analysis protocol

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e049882
Author(s):  
Jing Nong Liang ◽  
Savanna Budge ◽  
Austin Madriaga ◽  
Kara Meske ◽  
Derrick Nguyenton ◽  
...  
Keyword(s):  
Systematic Review ◽  
Spinal Cord ◽  
Quality Assessment ◽  
Meta Analysis ◽  
Neuromuscular Control ◽  
Patellofemoral Pain ◽  
Randomised Control Trial ◽  
Cross Sectional ◽  
Prospective Longitudinal ◽  
Brain And Spinal Cord

IntroductionReduced neuromuscular control due to altered neurophysiological functions of the central nervous system has been suggested to cause movement deficits in individuals with patellofemoral pain (PFP). However, the underlying neurophysiological measures of brain and spinal cord in this population remain to be poorly understood. The purpose of this systematic review is to evaluate the evidence for altered cortical and spinal cord functions in individuals with PFP.Methods and analysisThe protocol for conducting the review was prepared using the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guidelines. We will systematically search the literature that examines cortical and spinal cord functions in individuals with PFP, aged 18–45 years. The studies for cross-sectional, prospective, longitudinal, case–control and randomised control trial designs will be included from the following databases: PubMed (MEDLINE), EMBASE and Web of Science. Only studies published in English prior to 1 February 2021 will be included. The risk of bias and quality assessment will be performed using National Institutes of Health’s Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. We will conduct meta-analysis of the data where appropriate. Narrative synthesis will be taken if a meta-analysis is not possible.Ethics and disseminationThis is a systematic review from the existing literature and does not require ethical approval. The results of this study will be published in a peer-reviewed journal in the field of rehabilitation medicine, sports/orthopaedic medicine or neurology, regardless of the outcome.PROSPERO registration numberCRD42020212128.

Excretory dysfunction and quality of life after a spinal cord injury: A cross‐sectional study

2021 ◽  
Vol 30 (9-10) ◽  
pp. 1394-1402
Author(s):  
De Gong ◽  
Yingmin Wang ◽  
Lirong Zhong ◽  
Mengmeng Jia ◽  
Ting Liu ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cord Injury

scholarly journals Age-related variation in mobility independence among wheelchair users with spinal cord injury: A cross-sectional study

2016 ◽  
Vol 39 (2) ◽  
pp. 180-189 ◽  
Author(s):  
Timo Hinrichs ◽  
Veronika Lay ◽  
Ursina Arnet ◽  
Inge Eriks-Hoogland ◽  
Hans Georg Koch ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Wheelchair Users ◽  
Related Variation ◽  
Age Related ◽  
Cord Injury

Metabolic syndrome in people with a long-standing spinal cord injury: associations with physical activity and capacity

2016 ◽  
Vol 41 (11) ◽  
pp. 1190-1196 ◽  
Author(s):  
Sonja de Groot ◽  
Jacinthe J. Adriaansen ◽  
Marga Tepper ◽  
Govert J. Snoek ◽  
Lucas H.V. van der Woude ◽  
...  
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Aerobic Capacity ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Cord Injury ◽  
Peak Aerobic Capacity

This study investigated (i) the prevalence of the metabolic syndrome (MetS) in people with a long-standing spinal cord injury (SCI); (ii) whether personal or lesion characteristics are determinants of the MetS; and (iii) the association with physical activity or peak aerobic capacity on the MetS. In a cross-sectional study, persons with SCI (N = 223; time since injury of ≥10 years) were tested. The individual components of the MetS were assessed together with the physical activity measured by the Physical Activity Scale for Individuals with Physical Disabilities (PASIPD), while peak aerobic capacity was tested during a graded wheelchair exercise test on a treadmill. Thirty-nine percent of the participants had MetS. In a multivariate logistic regression analyses and after performing a backward regression analysis, only age and education were significant determinants of the MetS. A 10-year increase in age leads to a 1.5 times more chance to have the MetS. Furthermore, people with a low education will multiply the relative risk of MetS compared with people with high education by almost 2. With and without correcting for confounders, no significant relationship was found between PASIPD or peak aerobic capacity and the MetS. It can be concluded that the prevalence of the MetS is high (39%) in people with a long-standing SCI but is comparable to the general Dutch population. Older people and those with a lower education level are most at risk for the MetS. Physical activity and peak aerobic fitness were not related to the MetS in this group with a long-standing SCI.

Mechanisms leading to restoration of muscle size with exercise and transplantation after spinal cord injury

2000 ◽  
Vol 279 (6) ◽  
pp. C1677-C1684 ◽  
Author(s):  
Esther E. Dupont-Versteegden ◽  
René J. L. Murphy ◽  
John D. Houlé ◽  
Cathy M. Gurley ◽  
Charlotte A. Peterson
Keyword(s):  
Spinal Cord ◽  
Satellite Cell ◽  
Fiber Type ◽  
Cell Activity ◽  
Muscle Size ◽  
Spinal Cord Tissue ◽  
Cellular Mechanisms ◽  
Cross Sectional ◽  
Cord Injury ◽  
Nuclear Number

We have shown that cycling exercise combined with fetal spinal cord transplantation restored muscle mass reduced as a result of complete transection of the spinal cord. In this study, mechanisms whereby this combined intervention increased the size of atrophied soleus and plantaris muscles were investigated. Rats were divided into five groups ( n = 4, per group): control, nontransected; spinal cord transected at T10 for 8 wk (Tx); spinal cord transected for 8 wk and exercised for the last 4 wk (TxEx); spinal cord transected for 8 wk with transplantation of fetal spinal cord tissue into the lesion site 4 wk prior to death (TxTp); and spinal cord transected for 8 wk, exercised for the last 4 wk combined with transplantation 4 wk prior to death (TxExTp). Tx soleus and plantaris muscles were decreased in size compared with control. Exercise and transplantation alone did not restore muscle size in soleus, but exercise alone minimized atrophy in plantaris. However, the combination of exercise and transplantation resulted in a significant increase in muscle size in soleus and plantaris compared with transection alone. Furthermore, myofiber nuclear number of soleus was decreased by 40% in Tx and was not affected in TxEx or TxTp but was restored in TxExTp. A strong correlation ( r = 0.85) between myofiber cross-sectional area and myofiber nuclear number was observed in soleus, but not in plantaris muscle, in which myonuclear number did not change with any of the experimental manipulations. 5′-Bromo-2′-deoxyuridine-positive nuclei inside the myofiber membrane were observed in TxExTp soleus muscles, indicating that satellite cells had divided and subsequently fused into myofibers, contributing to the increase in myonuclear number. The increase in satellite cell activity did not appear to be controlled by the insulin-like growth factors (IGF), as IGF-I and IGF-II mRNA abundance was decreased in Tx soleus and plantaris, and was not restored with the interventions. These results indicate that, following a relatively long postinjury interval, exercise and transplantation combined restore muscle size. Satellite cell fusion and restoration of myofiber nuclear number contributed to increased muscle size in the soleus, but not in plantaris, suggesting that cellular mechanisms regulating muscle size differ between muscles with different fiber type composition.

scholarly journals Assessment of Daily Living of Patients with Spinal Cord Injury: A Cross-Sectional Study in Kermanshah

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Masoud Hatefi ◽  
AmirHosein Meisami ◽  
Alalleh Dalvand ◽  
Milad Borji
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Daily Living ◽  
Cross Sectional Study ◽  
Demographic Characteristics ◽  
Daily Activities ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cord Injury ◽  
The Impact

Background: Spinal cord injuries (SCI) are a variety of chronic diseases that various causes such as trauma may contribute to its onset. One of the problems in these patients is the problem of physical activity and, consequently, daily activities. Objectives: This study aimed to assess daily living of patients with SCI. Methods: In this descriptive cross-sectional study in 2019, 120 patients with SCI in Kermanshah were included in the study using purposive sampling. The instruments used in this study fell into two parts. One part included the demographic characteristics of the SCI patients, and the other part was a questionnaire of the rate of the Impact on Participation and Autonomy questionnaire (IPA-P). Data were analyzed by SPSS software version 16 using descriptive tests such as mean and standard deviation. Results: The result showed there was a significant relationship between demographic characteristics such as education (P < 0.007), time of spinal cord injury (P < 0.01), and income (P = 0.000). Also, the results showed there was a relationship between Autonomy and Participation, and the age of patients and their autonomy and participation decreased with age (P = 0.000, R = 0.72). Most of the patients had severe problems with daily activities. Also, most patients had very poor scores in relation to daily living activities. Conclusions: Considering the low rate of participation and autonomy in patients with SCI, it is suggested to conduct studies aimed at improving their self-care and social participation.

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