The Influence of Dissolved Metals in Cryolitic Melts on Hall Cell Current Inefficiency

Author(s):  
Ray D. Peterson ◽  
Xiangwen Wang
1997 ◽  
Vol 32 (1) ◽  
pp. 101-118 ◽  
Author(s):  
Q.J. ROCHFORT ◽  
W.E. Watt ◽  
J. Marsalek ◽  
B.C. Anderson ◽  
A.A. Crowder

Abstract Two subsurface flow constructed wetlands were tested for pollutant removal performance in conjunction with an on-line stormwater detention pond, in Kingston Township, Ontario. The 4.9 m2 wetland cells were filled with 9 mm limestone gravel, and planted with cattail, common reed and spike rush. Changes in nutrient (total organic carbon, PO43- and NH4+), suspended solids and metal (Cu, Pb, Zn) concentrations were used to assess performance. Contaminant removal occurred through a combination of physical, chemical and biological means. As with any biological system, variation in performance of stormwater wetlands can be expected to occur as a result of fluctuations in contaminant loading, contact time and ambient environmental conditions. Storm pond effluent was delivered in continuous flow through the wetlands (during baseflow and event conditions), with a detention time of 1 to 3 days. The wetlands were able to maintain removal rates of up to 39% for orthophosphate even during the more severe conditions of fall dieback. Average removal of suspended solids (46%) and dissolved metals (Cu 50%) remained similar throughout all tests. Organic carbon was reduced by less than 10% during these tests. Low nutrient levels in the pond effluent were supplemented by spiking with sources of carbon, nitrogen and phosphorus during pulsed loading conditions. Daily sampling produced a time series, which illustrated the rates of decline in concentration of nutrients. First order kinetic assimilation rates ranged from 1.7 d-1 for NH4002B to 0.12 d-1 for organic carbon, which were noticeably lower when compared with municipal and industrial wastewater treatment rates. Three methods of sizing stormwater wetlands (impervious surface area, volumetric load and kinetic reaction rates) were compared using the same design storm and data from this study. From this comparison it was seen that the kinetic sizing approach proved to be the most versatile, and allowed for adaptation to northern climatic conditions and anticipated nutrient loading.


Electronics ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1454
Author(s):  
Yoshihiro Sugiura ◽  
Toru Tanzawa

This paper describes how one can reduce the memory access time with pre-emphasis (PE) pulses even in non-volatile random-access memory. Optimum PE pulse widths and resultant minimum word-line (WL) delay times are investigated as a function of column address. The impact of the process variation in the time constant of WL, the cell current, and the resistance of deciding path on optimum PE pulses are discussed. Optimum PE pulse widths and resultant minimum WL delay times are modeled with fitting curves as a function of column address of the accessed memory cell, which provides designers with the ability to set the optimum timing for WL and BL (bit-line) operations, reducing average memory access time.


2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Nathan Tintle ◽  
Kristin Van De Griend ◽  
Rachel Ulrich ◽  
Randall D. Wade ◽  
Tena M. Baar ◽  
...  

Abstract Background Lack of sustainable access to clean drinking water continues to be an issue of paramount global importance, leading to millions of preventable deaths annually. Best practices for providing sustainable access to clean drinking water, however, remain unclear. Widespread installation of low-cost, in-home, point of use water filtration systems is a promising strategy. Methods We conducted a prospective, randomized, controlled trial whereby 16 villages were selected and randomly assigned to one of four treatment arms based on the installation location of Sawyer® PointONE™ filters (filter in both home and school; filter in home only; filter in school only; control group). Water samples and self-reported information on diarrhea were collected at multiple times throughout the study. Results Self-reported household prevalence of diarrhea decreased from 25.6 to 9.76% from installation to follow-up (at least 7 days, and up to 200 days post-filter installation). These declines were also observed in diarrhea with economic or educational consequences (diarrhea which led to medical treatment and/or missing school or work) with baseline prevalence of 9.64% declining to 1.57%. Decreases in diarrhea prevalence were observed across age groups. There was no evidence of a loss of efficacy of filters up to 200 days post-filter installation. Installation of filters in schools was not associated with decreases in diarrhea prevalence in school-aged children or family members. Unfiltered water samples both at schools and homes contained potential waterborne bacterial pathogens, dissolved heavy metals and metals associated with particulates. All dissolved metals were detected at levels below World Health Organization action guidelines. Conclusions This controlled trial provides strong evidence of the effectiveness of point-of-use, hollow fiber membrane filters at reducing diarrhea from bacterial sources up to 200 days post-installation when installed in homes. No statistically significant reduction in diarrhea was found when filters were installed in schools. Further research is needed in order to explore filter efficacy and utilization after 200 days post-installation. Trial registration ClinicalTrials.gov, NCT03972618. Registered 3 June 2019—retrospectively registered.


2021 ◽  
Vol 286 ◽  
pp. 116495
Author(s):  
Samuel T. Plunkett ◽  
Chengxiu Chen ◽  
Ramin Rojaee ◽  
Patrick Doherty ◽  
Yun Sik Oh ◽  
...  

2017 ◽  
Vol 262 ◽  
pp. 185-188 ◽  
Author(s):  
Alison Cox ◽  
Christopher G. Bryan

Previous agglomerate-scale heap bioleaching studies have outlined the variations in cell numbers of the liquid and attached phases during colonisation of sterilised ore by a pure culture. In this study, a mixed mesophilic culture was used in agglomerate-scale columns containing non-sterilised low-grade copper ore. Over a six - month period, columns were harvested at various intervals to provide snapshots of the metal distribution and the quantity, location, and ecological variations of mineral-oxidizing microbes within the ore bed. The initial colonisation period in this experiment was dissimilar to previous work, as the indigenous community was retained within the ore-bed throughout acid agglomeration. The overall colonisation phase lasted for approximately 1,000 hours until cell concentrations stabilised. In each column, less than 0.05% of the total cells were found in the leachate, 15-20% in the interstitial phase and the remaining ~80% were attached to the mineral surface. Once cell numbers had stabilised, interstitial cell concentrations were approximately 2,000× greater than those in the leachate. This difference persisted for the duration of the experiment. Copper concentrations in the two liquid phases generally decreased over time, but were on average 50× higher in the interstitial phase. Iron concentrations were more stable, but again were 30× higher in the interstitial phase. This demonstrates that that the difference in cell concentration between the leachate and interstitial phases cannot be explained through diffusion gradients within the system as it is much greater than those observed for the dissolved metals. It also shows that the specific environmental conditions of the interstitial and attached cells are very different to those inferred through analysis of leachates alone.


2014 ◽  
Vol 41 ◽  
pp. 176-188 ◽  
Author(s):  
Michael C. Moncur ◽  
Carol J. Ptacek ◽  
Masaki Hayashi ◽  
David W. Blowes ◽  
S. Jean Birks

2004 ◽  
Vol 287 (5) ◽  
pp. C1282-C1291 ◽  
Author(s):  
James K. Bubien ◽  
Hong-Long Ji ◽  
G. Yancey Gillespie ◽  
Catherine M. Fuller ◽  
James M. Markert ◽  
...  

Psalmotoxin 1 (a component of the venom of a West Indies tarantula) is a 40-amino acid peptide that inhibits cation currents mediated by acid-sensing ion channels (ASIC). In this study we performed electrophysiological experiments to test the hypothesis that Psalmotoxin 1 (PcTX1) inhibits Na+ currents in high-grade human astrocytoma cells (glioblastoma multiforme, or GBM). In whole cell patch-clamped cultured GBM cells, the peptide toxin quickly and reversibly inhibited both inward and outward current with an IC50 of 36 ± 2 pM. The same inhibition was observed in freshly resected GBM cells. However, when the same experiment was performed on normal human astrocytes, the toxin failed to inhibit the whole cell current. We also determined a cationic selectivity sequence for inward currents in three cultured GBM cell lines (SK-MG-1, U87-MG, and U251-MG). The selectivity sequence yielded a unique biophysical fingerprint with inward K+ conductance approximately fourfold greater than that of Na+, Li+, and Ca2+. These observations suggest that PcTX1 may prove useful in determining whether GBM cells express a specific ASIC-containing ion channel type that can serve as a target for both diagnostic and therapeutic treatments of aggressive malignant gliomas.


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