scholarly journals Role of VR Throughout the Life of Low Volume Products Towards Digital Extended Enterprises

Author(s):  
Simo-Pekka Leino ◽  
Antti Pulkkinen ◽  
Juha-Pekka Anttila
Keyword(s):  
Viruses ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 667 ◽  
Author(s):  
Ling Deng ◽  
Ronalds Silins ◽  
Josué L. Castro-Mejía ◽  
Witold Kot ◽  
Leon Jessen ◽  
...  

The human gut microbiome (GM) plays an important role in human health and diseases. However, while substantial progress has been made in understanding the role of bacterial inhabitants of the gut, much less is known regarding the viral component of the GM. Bacteriophages (phages) are viruses attacking specific host bacteria and likely play important roles in shaping the GM. Although metagenomic approaches have led to the discoveries of many new viruses, they remain largely uncultured as their hosts have not been identified, which hampers our understanding of their biological roles. Existing protocols for isolation of viromes generally require relatively high input volumes and are generally more focused on extracting nucleic acids of good quality and purity for down-stream analysis, and less on purifying viruses with infective capacity. In this study, we report the development of an efficient protocol requiring low sample input yielding purified viromes containing phages that are still infective, which also are of sufficient purity for genome sequencing. We validated the method through spiking known phages followed by plaque assays, qPCR, and metagenomic sequencing. The protocol should facilitate the process of culturing novel viruses from the gut as well as large scale studies on gut viromes.


2014 ◽  
Vol 8 (2) ◽  
pp. 29-42 ◽  
Author(s):  
Rodney Paul ◽  
Andrew P. Weinbach ◽  
Kenneth Small

Using betting market volume data for the NFL and NCAA Football, we examine the role of betting volume as it relates to bettor biases, forecast accuracy, and volume-based betting market strategies.  We find that betting volume has a statistically significant effect on the percentage bet on the favorite, but its impact is different between the two levels of football.  Increased betting volume was shown to not have an impact on forecast accuracy in the sports.  Simple betting simulations revealed that underdogs win more than implied by efficiency in low-volume NFL games, but other strategies did not reject market efficiency.


Author(s):  
D. Segura Velandia ◽  
R. Monfared ◽  
A. A. West ◽  
P. P. Conway ◽  
D. C. Whalley ◽  
...  

2011 ◽  
Vol 13 (9) ◽  
pp. e276-e283 ◽  
Author(s):  
P. Mroczkowski ◽  
R. Kube ◽  
H. Ptok ◽  
U. Schmidt ◽  
S. Hac ◽  
...  

2010 ◽  
Vol 4 (1) ◽  
pp. 135-144 ◽  
Author(s):  
Patricia Gullón ◽  
Enma Conde ◽  
Andrés Moure ◽  
Herminia Domínguez ◽  
Juan Carlos Parajó

The role of biorefineries in the production of energy and chemicals from biomass of lignocellulosic nature is reviewed. Special attention is devoted to biorefinery schemes dealing with the fractionation of lignocellulosic raw materials by chemical treatments. The potential of hydrothermal treatments as the first stage of future biorefineries is discussed. Special attention is devoted to the low-volume, high-added value products that can be solubilized by this type of technology.


2021 ◽  
Vol 22 (17) ◽  
pp. 9573
Author(s):  
William Tyler Turchan ◽  
Sean P. Pitroda ◽  
Ralph R. Weichselbaum

Radiotherapy and immunotherapy are most effective as cancer therapies in the setting of low-volume disease. Although initial studies of radio-immunotherapy in patients with metastatic cancer have not confirmed the efficacy of this approach, the role of radio-immunotherapy in patients with limited metastatic burden is unclear. We propose that further investigation of radio-immunotherapy in metastatic patients should focus upon patients with oligometastatic disease.


Procedia CIRP ◽  
2021 ◽  
Vol 104 ◽  
pp. 1452-1457
Author(s):  
Kerstin Johansen ◽  
Sagar Rao ◽  
Milad Ashourpour

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