Gene Expression Analysis by Fuzzy and Hybrid Fuzzy Classification

Author(s):  
Gerald Schaefer ◽  
Tomoharu Nakashima ◽  
Hisao Ishibuchi
Author(s):  
Gerald Schaefer ◽  
Tomoharu Nakashima

Microarray studies and gene expression analysis have received significant attention over the last few years and provide many promising avenues towards the understanding of fundamental questions in biology and medicine. In this chapter, the authors show that a combined GA-fuzzy classification system can be employed for effective mining of gene expression data. The applied classifier consists of a set of fuzzy if-then rules that allow for accurate non-linear classification of input patterns. A small number of fuzzy if-then rules are selected through means of a genetic algorithm, and are capable of providing a compact classifier for gene expression analysis. Experimental results on various well-known gene expression datasets confirm good classification performance of our approach.


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