Effect of Aortic Arch Geometry on Pulsatile Blood Flow: Flow Pattern and Wall Shear Stress

Author(s):  
P. Vasava ◽  
M. Dabagh ◽  
P. Jalali
2020 ◽  
Vol 88 (2) ◽  
Author(s):  
Yuxi Jia ◽  
Kumaradevan Punithakumar ◽  
Michelle Noga ◽  
Arman Hemmati

Abstract The characteristics of blood flow in an abnormal pediatric aorta with an aortic coarctation and aortic arch narrowing are examined using direct numerical simulations and patient-specific boundary conditions. The blood flow simulations of a normal pediatric aorta are used for comparison to identify unique flow features resulting from the aorta geometrical anomalies. Despite flow similarities compared to the flow in normal aortic arch, the flow velocity decreases with an increase in pressure, wall shear stress, and vorticity around both anomalies. The presence of wall shear stresses in the trailing indentation region and aorta coarctation opposing the primary flow direction suggests that there exist recirculation zones in the aorta. The discrepancy in relative flowrates through the top and bottom of the aorta outlets, and the pressure drop across the coarctation, implies a high blood pressure in the upper body and a low blood pressure in the lower body. We propose using flow manipulators prior to the aortic arch and coarctation to lower the wall shear stress, while making the recirculation regions both smaller and weaker. The flow manipulators form a guide to divert and correct blood flow in critical regions of the aorta with anomalies.


Author(s):  
Xiao-Yong Shen ◽  
M. Barzegar Gerdroodbary ◽  
Amin Poozesh ◽  
Amir Musa Abazari ◽  
S. Misagh Imani

In recent decades, cardiovascular disease and stroke are recognized as the most important reason for the high death rate. Irregular bloodstream and the circulatory system are the main reason for this issue. In this paper, Computational Fluid dynamic method is employed to study the impacts of the flow pattern inside the cerebral aneurysm for detection of the hemorrhage of the aneurysm. To achieve a reliable outcome, blood flow is considered as a non-Newtonian fluid with a power-law model. In this study, the influence of the blood viscosity and velocity on the pressure distribution and average wall shear stress (AWSS) are comprehensively studied. Moreover, the flow pattern inside the aneurysm is investigated to obtain the high-risk regions for the rupture of the aneurysm. Our results indicate that the wall shear stress (WSS) increases with increasing blood flow velocity. Furthermore, the risk of aneurysm rupture is considerably increased when the AWSS increases more than 0.6. Indeed, the blood flow with high viscosity expands the high-risk region on the wall of the aneurysm. Blood flow indicates that the angle of the incoming bloodstream is substantially effective in the high-risk region on the aneurysm wall. The augmentation of the blood velocity and vortices considerably increases the risk of hemorrhage of the aneurysm.


2003 ◽  
Vol 125 (2) ◽  
pp. 207-217 ◽  
Author(s):  
E. A. Finol ◽  
K. Keyhani ◽  
C. H. Amon

In the abdominal segment of the human aorta under a patient’s average resting conditions, pulsatile blood flow exhibits complex laminar patterns with secondary flows induced by adjacent branches and irregular vessel geometries. The flow dynamics becomes more complex when there is a pathological condition that causes changes in the normal structural composition of the vessel wall, for example, in the presence of an aneurysm. This work examines the hemodynamics of pulsatile blood flow in hypothetical three-dimensional models of abdominal aortic aneurysms (AAAs). Numerical predictions of blood flow patterns and hemodynamic stresses in AAAs are performed in single-aneurysm, asymmetric, rigid wall models using the finite element method. We characterize pulsatile flow dynamics in AAAs for average resting conditions by means of identifying regions of disturbed flow and quantifying the disturbance by evaluating flow-induced stresses at the aneurysm wall, specifically wall pressure and wall shear stress. Physiologically realistic abdominal aortic blood flow is simulated under pulsatile conditions for the range of time-average Reynolds numbers 50⩽Rem⩽300, corresponding to a range of peak Reynolds numbers 262.5⩽Repeak⩽1575. The vortex dynamics induced by pulsatile flow in AAAs is depicted by a sequence of four different flow phases in one period of the cardiac pulse. Peak wall shear stress and peak wall pressure are reported as a function of the time-average Reynolds number and aneurysm asymmetry. The effect of asymmetry in hypothetically shaped AAAs is to increase the maximum wall shear stress at peak flow and to induce the appearance of secondary flows in late diastole.


2008 ◽  
Vol 49 (7) ◽  
pp. 806-814 ◽  
Author(s):  
Binbin Sui ◽  
Peiyi Gao ◽  
Yan Lin ◽  
Bing Gao ◽  
Long Liu ◽  
...  

2020 ◽  
Vol 20 (03) ◽  
pp. 2050013
Author(s):  
AHMED BAKHIT ALANAZI ◽  
MOHAMED YACIN SIKKANDAR ◽  
MOHAMED IBRAHIM WALY

In this paper, a numerical estimation of wall shear stress (WSS) in a compliant Thoracic Aorta (TA) with aneurysm is modeled and the hemodynamic pattern is studied using Computational Fluid Dynamics (CFD). Thoracic Aortic Aneurysm (TAA) is an excessively localized enlargement of TA caused by weakness in the arterial wall and it can rupture the inner wall intima and continue on to the outer wall adventitia. WSS is a tangential force exerted by blood flow on the vessel wall, and its estimation is clinically very important because any change in WSS is considered as a vital cue in the onset of aneurysm. In this work, a three-dimensional (3D) model of a TAA reconstructed from computed tomography (CT) images comprising of 600 slices with 1-mm resolution from neck to hip is considered and patient-specific simulations have been carried out in compliant TA under rest and exercise conditions. The findings show that the change in wall geometry was marginal due to variation in pressure forces inside and is not the primary source for expansion of an aneurysm. It was inferred that expansion was rather due to thinning of the wall, owing to damage caused to the inner lining of the tissues, at regions of high WSS. It was found that the geometry extraction is important as any change in length causes a corresponding variation in mass flow through it. Although mass conservation is maintained irrespective of the length, it does affect the rate of flow due to shifting in the pressure boundary conditions with the length as it varies the pressure inside the system. Modeling of the geometry is very important as the change in mass flow will affect the outlet velocity and strength of vortices. Surprisingly, the split-up of flow is consistent but the geometric change in the model has no effect on WSS values and flow pattern. The results of this study provide important information such as blood flow pattern and pressure drops in the compliant TA on WSS estimations with TAA diseases.


2012 ◽  
Vol 2012 ◽  
pp. 1-14 ◽  
Author(s):  
Paritosh Vasava ◽  
Payman Jalali ◽  
Mahsa Dabagh ◽  
Pertti J. Kolari

A three-dimensional computer model of human aortic arch with three branches is reproduced to study the pulsatile blood flow with Finite Element Method. In specific, the focus is on variation of wall shear stress, which plays an important role in the localization and development of atherosclerotic plaques. Pulsatile pressure pulse is used as boundary condition to avoid flow entry development, and the aorta walls are considered rigid. The aorta model along with boundary conditions is altered to study the effect of hypotension and hypertension. The results illustrated low and fluctuating shear stress at outer and inner wall of aortic arch, proximal wall of branches, and entry region. Despite the simplification of aorta model, rigid walls and other assumptions results displayed that hypertension causes lowered local wall shear stresses. It is the sign of an increased risk of atherosclerosis. The assessment of hemodynamics shows that under the flow regimes of hypotension and hypertension, the risk of atherosclerosis localization in human aorta may increase.


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