Autonomous Units and Their Semantics – The Concurrent Case

2010 ◽  
pp. 102-120 ◽  
Author(s):  
Hans-Jörg Kreowski ◽  
Sabine Kuske
Keyword(s):  
Concurrent Case

scholarly journals Simultaneous Coexistence of Thyrotropin-Prolactin-Secreting Adenoma and Papillary Thyroid Carcinoma

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Somaya Safi ◽  
Yousra Benabdelfedil ◽  
Sara Derrou ◽  
Faycal El Guendouz
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Complete Response ◽  
Thyroid Stimulating Hormone ◽  
Suppressive Therapy ◽  
Papillary Thyroid ◽  
Case Presentation ◽  
Moroccan Woman ◽  
Potential Link ◽  
Concurrent Case

Background. The thyrotropin-secreting adenomas are very rare and even more rare when they simultaneously coexist with thyroid carcinoma. So far, only sixteen cases have been reported in the literature. Here, we present a unique case of successful management of a concurrent case of thyrotropin-prolactinoma with papillary thyroid carcinoma. Case Presentation. A 50-year-old Moroccan woman underwent a total thyroidectomy and complementary totalization by iratherapy for papillary thyroid carcinoma, who presented persistence of an inappropriate secretion of the thyroid-stimulating hormone (TSH > 4 mUI/L) despite of levothyroxine suppressive therapy (300 μg/d). After eliminating noncompliance, interfering medicines, and thyroid malabsorption, a pituitary adenoma (12 mm) was documented at magnetic resonance imaging. The patient has had transsphenoidal pituitary adenomectomy with histology confirming a thyrotropin-prolactin-secreting adenoma. After surgery and lanreotide treatment failures, we noted a complete response (TSH < 0.5) with cabergoline treatment (3 mg/week). Conclusion. The unusual association of thyroid adenocarcinoma and TSHoma enriches the hypothesis of a potential link between thyrotropic hypersecretion and thyroid carcinogenesis. Our case also illustrates the difficulty of monitoring thyroid carcinoma in nonremission of a TSHoma.

First documented case of human infection with ovine Shiga-toxin-producingEscherichia coliserotype O52:H45

2014 ◽  
Vol 60 (6) ◽  
pp. 417-418 ◽  
Author(s):  
Sadjia Bekal ◽  
Danielle Ramsay ◽  
Fabien Rallu ◽  
Pierre Pilon ◽  
Matthew Gilmour ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Shiga Toxin ◽  
Molecular Typing ◽  
Human Infection ◽  
Causal Agent ◽  
Child Exposure ◽  
Documented Case ◽  
Sheep Meat ◽  
Concurrent Case

We report a concurrent case of infection with non-O157 Shiga-toxin-producing Escherichia coli (STEC) strain in an 8-month-old child. Laboratory and epidemiological investigations indicated child exposure to contaminated sheep meat following the Muslim feast of sacrifice (Eid al-Adha). Microbiological and molecular typing confirmed that the ovine strain O52:H45 (stx1+, eae–, hlyA–) was the causal agent. This is the first documented case of human infection to this STEC serotype.

scholarly journals Radiative and climate impacts of a large volcanic eruption during stratospheric sulfur geoengineering

2015 ◽  
Vol 15 (15) ◽  
pp. 21837-21881 ◽  
Author(s):  
A. Laakso ◽  
H. Kokkola ◽  
A.-I. Partanen ◽  
U. Niemeier ◽  
C. Timmreck ◽  
...  
Keyword(s):  
Volcanic Eruption ◽  
Climate Model ◽  
Regional Climate ◽  
Volcanic Eruptions ◽  
Stratospheric Aerosol ◽  
Climate Impacts ◽  
Solar Radiation Management ◽  
Atmospheric Conditions ◽  
Concurrent Case ◽  
Radiation Management

Abstract. Both explosive volcanic eruptions, which emit sulfur dioxide into the stratosphere, and stratospheric geoengineering via sulfur injections can potentially cool the climate by increasing the amount of scattering particles in the atmosphere. Here we employ a global aerosol-climate model and an earth system model to study the radiative and climate impacts of an erupting volcano during solar radiation management (SRM). According to our simulations, the radiative impacts of an eruption and SRM are not additive: in the simulated case of concurrent eruption and SRM, the peak increase in global forcing is about 40 % lower compared to a corresponding eruption into a clean background atmosphere. In addition, the recovery of the stratospheric sulfate burden and forcing was significantly faster in the concurrent case since the sulfate particles grew larger and thus sedimented faster from the stratosphere. In our simulation where we assumed that SRM would be stopped immediately after a volcano eruption, stopping SRM decreased the overall stratospheric aerosol load. For the same reasons, a volcanic eruption during SRM lead to only about 1/3 of the peak global ensemble-mean cooling compared to an eruption under unperturbed atmospheric conditions. Furthermore, the global cooling signal was seen only for 12 months after the eruption in the former scenario compared to over 40 months in the latter. In terms of the global precipitation rate, we obtain a 36 % smaller decrease in the first year after the eruption and again a clearly faster recovery in the concurrent eruption and SRM scenario. We also found that an explosive eruption could lead to significantly different regional climate responses depending on whether it takes place during geoengineering or into an unperturbed background atmosphere. Our results imply that observations from previous large eruptions, such as Mt Pinatubo in 1991, are not directly applicable when estimating the potential consequences of a volcanic eruption during stratospheric geoengineering.

scholarly journals Morgellons: a novel dermatological perspective as the multisystem infective disease borreliosis

F1000Research ◽  
2013 ◽  
Vol 2 ◽  
pp. 118 ◽  
Author(s):  
Peter Mayne ◽  
John S English ◽  
Edward J Kilbane ◽  
Jennie M Burke ◽  
Marianne J Middelveen ◽  
...  
Keyword(s):  
Medical Profession ◽  
Scientific Data ◽  
The Novel ◽  
Dermatitis Artefacta ◽  
Disease Complex ◽  
System Disease ◽  
Co Morbidity ◽  
Infective Disease ◽  
Concurrent Case ◽  
Novel Model

Morgellons disease (MD) is a term that has been used in the last decade to describe filaments that can be found in human epidermis. It is the subject of considerable debate within the medical profession and is often labeled as delusions of parasitosis or dermatitis artefacta. This view is challenged by recent published scientific data put forward between 2011-2013 identifying the filaments found in MD as keratin and collagen based and furthermore associated with spirochetal infection. The novel model of the dermopathy put forward by those authors is further described and, in particular, presented as a dermal manifestation of the multi-system disease complex borreliosis otherwise called Lyme disease. A differential diagnosis is drawn from a dermatological perspective. The requirements for a diagnosis of delusional disorder from a psychiatric perspective are clarified and the psychological or psychiatric co-morbidity that can be found with MD cases is presented. A concurrent case incidence is also included. Management of the multisytem disease complex is discussed both in general and from a dermatological perspective. Finally replacement of the term ‘Morgellons’ by ‘borrelial dermatitis’ is proposed within the profession.

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