Review of Coated Conductor Superconductor Wire Scale-up Research in the U.S.

Author(s):  
Robert H. Hammond
Author(s):  
Kara Palamountain ◽  
Tim Calkins

It is January 2017, and Nikki Tyler, market access advisor at the U.S. Agency for International Development's Center for Accelerating Innovation and Impact, must recommend an actionable strategy for how to use the $10 million contributed by global donors and foundations to scale up the use of chlorhexidine in Nigeria. It was clear that chlorhexidine, a substance applied to newborns' umbilical cord stumps to prevent infection, could reduce infant mortality significantly. However, changing behavior would be an enormous challenge. This case gives students an appreciation for the importance and complexity of global health issues, along with an understanding of key analytic techniques for approaching a complex market situation. Students quickly learn that there are no easy answers to encouraging chlorhexidine's greater use. To develop a plan, it is essential to complete detailed analyses, study insights and motivations, and ultimately compare different possible solutions, considering efficiency and efficacy.


2011 ◽  
Vol 21 (3) ◽  
pp. 3055-3058 ◽  
Author(s):  
Yunfei Qiao ◽  
Yimin Chen ◽  
Xuming Xiong ◽  
Sungjin Kim ◽  
Vladimir Matias ◽  
...  

2016 ◽  
Vol 29 (3) ◽  
pp. 305-346 ◽  
Author(s):  
James Bergman

ArgumentThe history of meteorology has focused a great deal on the “scaling up” of knowledge infrastructures through the development of national and global observation networks. This article argues that such efforts to scale up were paralleled by efforts to define a place for local knowledge. By examining efforts of the Blue Hill Meteorological Observatory, near Boston, Massachusetts, to issuelocalweather forecasts that competed with the centralized forecasts of the U.S. Signal Service, this article finds that Blue Hill, as a user of the Signal Service's observation network, developed a new understanding of local knowledge by combining local observations of the weather with the synoptic maps afforded by the nationwide telegraph network of the U.S. Signal Service. Blue Hill used these forecasts not only as a service, but also as evidence of the superiority of its model of local forecasting over the Signal Service's model, and in the process opened up larger questions about the value of a weather forecast and the value of different kinds of knowledge in meteorology.


Author(s):  
William B. Bonvillian ◽  
Peter L. Singer

This chapter reviews the U.S. manufacturing decline in the first decade of the twenty-first century, examining this from a series of dimensions, including the critical relationship between the production stage and the other parts of its innovation system. The profound challenge to U.S. production in the 1970s and 1980s from Japan's quality manufacturing model and its accompanying technology and process advances, which dramatically disrupted U.S. production practices, is the first issue that must be understood. The chapter then explores the rise of China's manufacturing economy; its innovative new production scale-up approaches knocked the United States into second place in world manufacturing output in a remarkably short period. Accompanying that rise was a parallel and related rise in distributed production by U.S. firms, with outsourcing of production stages and corresponding issues of “innovate here/produce there,” which could lead to “produce there/innovate there.”


Author(s):  
Su Wang ◽  
Chari Cohen ◽  
Amy S. Tang ◽  
Camilla S. Graham

Abstract Purpose of Review The World Health Organization has set a target for the elimination of hepatitis B virus (HBV) infection as a public health threat by 2030, but the U.S. is not currently on track. In this review, we describe specific barriers to HBV elimination, provide examples of potential solutions, and offer recommendations for how the U.S. can reach HBV elimination goals. Recent Findings In the U.S., there are many barriers to eliminating hepatitis B, worsened by the siloing of healthcare and public health services. In recent years, we have not seen progress toward improving HBV screening or adult vaccination, and acute cases are on the rise. Current policies, guidelines, and recommendations can hinder elimination progress. Summary Simple policy and guideline changes will allow us to decentralize and scale-up hepatitis B screening, vaccination, and care. Dismantling current barriers will be critical to eliminating hepatitis B in the U.S.


2002 ◽  
Author(s):  
V. Selvamanickam ◽  
Y. Li ◽  
S. Sathiaraju ◽  
Y. Qiao ◽  
K. Zdun ◽  
...  
Keyword(s):  
Scale Up ◽  

Author(s):  
R. R. Hengst ◽  
D. N. Heichel ◽  
J. E. Holowczak ◽  
A. P. Taglialavore ◽  
B. J. McEntire

For over ten years, injection molding and slip casting have been actively developed as forming techniques for ceramic gas turbine components. Co-development of these two processes has continued within the U.S. DOE-sponsored Advanced Turbine Technology Application Project (ATTAP). Progress within ATTAP with respect to these two techniques is summarized. A critique and comparison of the two processes are given. Critical aspects of both processes with respect to size, dimensional control, material properties, quality, cost, and potential for manufacturing scale-up are discussed.


Author(s):  
M. W. Rettler ◽  
M. L. Easley ◽  
J. R. Smyth

Under the U.S. Dept. of Energy/National Aeronautics and Space Administration (DOE/NASA) funded Ceramic Turbine Engine Demonstration Project, formerly the Advanced Turbine Technology Applications Project (ATTAP), AlliedSignal Engines is addressing the remaining critical concerns slowing the commercialization of structural ceramics in gas turbine engines. These issues include demonstration of ceramic component reliability, readiness of ceramic suppliers to support ceramic production needs, and development of ceramic design technologies. The AlliedSignal/Garrett Model 331-200[CT] Auxiliary Power Unit (APU) is being used as a ceramics test bed engine. The first-stage turbine blades and nozzles were redesigned using ceramic materials, employing the design methods developed during the earlier DOE/NASA-funded Advanced Gas Turbine (AGT) and ATTAP programs. Ceramic engine components have been fabricated and are now being evaluated in laboratory engine testing. The fabrication processes for these components will provide the framework for a demonstration of manufacturing process scale-up to the minimum level for commercial viability. The laboratory engine testing is helping to refine the component designs and focus the development of ceramic component technologies. Extended engine endurance testing and field testing in commercial aircraft is planned to demonstrate ceramic component reliability. Significant progress has been made during 1994. An engine with ceramic turbine nozzles was successfully operated and engine tests in the laboratory are continuing to gather useful data. An engine equipped with ceramic blades was also tested, but blade fractures occurred, interrupting operation. An extensive investigation has identified possible vibration and contact problems. Investigative evaluation efforts are continuing to identify the problem source and determine go-forward plans for ceramic blade development. Component design technologies have progressed in the areas of modeling particle impact pulverization, development of a ceramic hot corrosion environmental life model, and methods for evaluating ceramic contact damage. The planned ceramic manufacturing scale-up was initiated with two ceramics vendors, Norton Advanced Ceramics (East Granby, CT) and AlliedSignal Ceramic Components (Torrance, CA). The scaleup demonstration program is emphasizing improvement of ceramic processing yields and increased production rates. Work summarized in this paper was funded by the U.S. Dept. of Energy (DOE) Office of Transportation Technologies, as part of the Turbine Engine Technologies Program, and administered by the NASA Lewis Research Center, Cleveland, OH under Contract No. DEN3-335.


2020 ◽  
Vol 69 (12) ◽  
pp. 329-334
Author(s):  
Michael Melgar ◽  
Catherine Nichols ◽  
J. Sean Cavanaugh ◽  
Hannah L. Kirking ◽  
Diya Surie ◽  
...  

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