Future Directions for Clinical Research

1986 ◽  
pp. 289-297
Author(s):  
David B. Sachar
Keyword(s):  
Clinical Research ◽  
Future Directions

scholarly journals EXPRESS: What’s New in Pulmonary Hypertension Clinical Research: Lessons from the Best Abstracts at the 2020 American Thoracic Society International Conference

2021 ◽  
pp. 204589402110407
Author(s):  
Andrew J Sweatt ◽  
Raju Reddy ◽  
Farbod Rahaghi ◽  
Nadine Al-Naamani
Keyword(s):  
Pulmonary Hypertension ◽  
Clinical Research ◽  
Chronic Thromboembolic Pulmonary Hypertension ◽  
American Thoracic Society ◽  
Future Directions ◽  
International Conference ◽  
Metabolic Dysregulation ◽  
Current State ◽  
Thromboembolic Pulmonary Hypertension ◽  
Pulmonary Arterial

In this conference paper, we review the 2020 American Thoracic Society (ATS) International Conference session titled, “What’s New in Pulmonary Hypertension Clinical Research: Lessons from the Best Abstracts”. This virtual mini-symposium took place on October 21, 2020, in lieu of the annual in-person ATS International Conference which was cancelled due to the COVID-19 pandemic. Seven clinical research abstracts were selected for presentation in the session, which encompassed five major themes: (1) standardizing diagnosis and management of pulmonary hypertension, (2) improving risk assessment in pulmonary arterial hypertension, (3) evaluating biomarkers of disease activity, (4) understanding metabolic dysregulation across the spectrum of pulmonary hypertension, and (5) advancing knowledge in chronic thromboembolic pulmonary hypertension. Focusing on these five thematic contexts we review the current state of knowledge, summarize presented research abstracts, appraise their significance and limitations, and then discuss relevant future directions in pulmonary hypertension clinical research.

scholarly journals Academic neurosurgery in the UK: present and future directions

2019 ◽  
Vol 95 (1128) ◽  
pp. 524-530
Author(s):  
Mueez Waqar ◽  
Benjamin M Davies ◽  
Rasheed Zakaria ◽  
Damiano G Barone ◽  
Angelos G Kolias ◽  
...  
Keyword(s):  
Clinical Research ◽  
Basic Science ◽  
Academic Training ◽  
Future Directions ◽  
Individual Level ◽  
International Standing ◽  
Personal Accounts ◽  
The Individual ◽  
The Uk

Academic neurosurgery encompasses basic science and clinical research efforts to better understand and treat diseases of relevance to neurosurgical practice, with the overall aim of improving treatment and outcome for patients. In this article, we provide an overview of the current and future directions of British academic neurosurgery. Training pathways are considered together with personal accounts of experiences of structured integrated clinical academic training and unstructured academic training. Life as an academic consultant is also described. Funding is explored, for the specialty as a whole and at the individual level. UK academic neurosurgical organisations are highlighted. Finally, the UK’s international standing is considered.

scholarly journals Considerations and Future Directions for Conducting Clinical Research With Pediatric Populations During the COVID-19 Pandemic

2020 ◽  
Vol 45 (7) ◽  
pp. 720-724 ◽  
Author(s):  
Colleen Stiles-Shields ◽  
Jill M Plevinsky ◽  
Alexandra M Psihogios ◽  
Grayson N Holmbeck
Keyword(s):  
Clinical Research ◽  
Future Directions ◽  
Pediatric Populations

Future Directions in Clinical Research in Wilms Tumor

1995 ◽  
Vol 9 (6) ◽  
pp. 1329-1339 ◽  
Author(s):  
Daniel M. Green ◽  
Max J. Coppes
Keyword(s):  
Clinical Research ◽  
Wilms Tumor ◽  
Future Directions

Pancreatic Adenocarcinoma in the Older Adult

2010 ◽  
Vol 06 ◽  
pp. 53
Author(s):  
Arlene A Gayle ◽  
Noelle K LoConte ◽  
◽  
Keyword(s):  
Older Adults ◽  
Clinical Research ◽  
Effective Treatment ◽  
Pancreatic Adenocarcinoma ◽  
Older Adult ◽  
Treatment Options ◽  
Medical Conditions ◽  
Future Directions ◽  
Large Numbers

Pancreatic adenocarcinoma is common among older adults, who may be more frail or have comorbid medical conditions that make treatment more challenging. Pancreatic adenocarcinoma is a lethal malignancy with relatively few effective treatment options. To date, most clinical research has not enrolled large numbers of older adults, despite this being the demographic predominantly affected by this illness. In this article, etiology and treatments for pancreatic adenocarcinoma are reviewed with a particular emphasis on studies that have examined matters relating to treating older adults; future directions for research are also explored.

scholarly journals Levobupivacaine for regional blockades in orthopedics and traumatology in children: recent evidence and future directions

2018 ◽  
Vol 6 (4) ◽  
pp. 77-83
Author(s):  
Gleb E. Ulrikh ◽  
Dmitri V. Zabolotskii ◽  
Yuri S. Aleksandrovich ◽  
Viktor A. Koryachkin ◽  
Sevir N. Nezabudkin ◽  
...  
Keyword(s):  
Pain Relief ◽  
Literature Review ◽  
Clinical Research ◽  
Clinical Data ◽  
Pediatric Patients ◽  
Future Directions ◽  
Different Ages

Levobupivacaine is an amide anesthetic, levorotatory isomer of bupivacaine. This literature review aimed to present the possibilities of levobupivacaine in the implementation of blockades for anesthesia in traumatology and orthopedics in children. Levobupivacaine is widely used for analgesia for orthopedic interventions in adults and has become an alternative to the less safe bupivacaine. The actions of levobupivacaine, bupivacaine, and ropivacaine in the implementation of neuroaxial and peripheral blockades, and the infiltration of postoperative wounds in children were compared in the present study. Levobupivacaine has been confirmed to be safe compared with bupivacaine in pediatric patients. Studies in children of different ages comparing levobupivacaine and ropivacaine, used for anesthesia in traumatology and orthopedics, indicate the same or greater analgesic potential of levobupivacaine, with a similar level of safety. Compared with ropivacaine, levobupivacaine provides comparable pain relief at lower concentrations. The presented clinical data of levobupivacaine use in children allow the expansion of the indications for anesthesia in orthopedics and traumatology. Clinical research should be continued to compare the effectiveness of different concentrations of levobupivacaine and ropivacaine in larger groups of pediatric patients. Relevant papers were obtained by searching PubMed and Scopus databases.

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