scholarly journals Considerations and Future Directions for Conducting Clinical Research With Pediatric Populations During the COVID-19 Pandemic

2020 ◽  
Vol 45 (7) ◽  
pp. 720-724 ◽  
Author(s):  
Colleen Stiles-Shields ◽  
Jill M Plevinsky ◽  
Alexandra M Psihogios ◽  
Grayson N Holmbeck
2021 ◽  
pp. 204589402110407
Author(s):  
Andrew J Sweatt ◽  
Raju Reddy ◽  
Farbod Rahaghi ◽  
Nadine Al-Naamani

In this conference paper, we review the 2020 American Thoracic Society (ATS) International Conference session titled, “What’s New in Pulmonary Hypertension Clinical Research: Lessons from the Best Abstracts”. This virtual mini-symposium took place on October 21, 2020, in lieu of the annual in-person ATS International Conference which was cancelled due to the COVID-19 pandemic. Seven clinical research abstracts were selected for presentation in the session, which encompassed five major themes: (1) standardizing diagnosis and management of pulmonary hypertension, (2) improving risk assessment in pulmonary arterial hypertension, (3) evaluating biomarkers of disease activity, (4) understanding metabolic dysregulation across the spectrum of pulmonary hypertension, and (5) advancing knowledge in chronic thromboembolic pulmonary hypertension. Focusing on these five thematic contexts we review the current state of knowledge, summarize presented research abstracts, appraise their significance and limitations, and then discuss relevant future directions in pulmonary hypertension clinical research.


Author(s):  
Luke Gelinas ◽  
Jennifer C. Kesselheim

Social media use has increased exponentially across all demographics. With social media’s widespread popularity comes an increased potential for research sponsors and investigators to use it as an effective tool for recruiting individuals into clinical research. Despite this, there has been relatively little attention paid to the general ethical issues implicated in social media recruitment and even less attention paid to the distinct ethical issues raised by using social media to recruit pediatric populations more specifically. This chapter examines these issues, providing an overview of the use of social media in clinical practice, an assessment of the general ethical issues associated with social media recruitment, and analysis of the potential risks and benefits of using social media to target adolescents for recruitment into clinical research.


2019 ◽  
Vol 95 (1128) ◽  
pp. 524-530
Author(s):  
Mueez Waqar ◽  
Benjamin M Davies ◽  
Rasheed Zakaria ◽  
Damiano G Barone ◽  
Angelos G Kolias ◽  
...  

Academic neurosurgery encompasses basic science and clinical research efforts to better understand and treat diseases of relevance to neurosurgical practice, with the overall aim of improving treatment and outcome for patients. In this article, we provide an overview of the current and future directions of British academic neurosurgery. Training pathways are considered together with personal accounts of experiences of structured integrated clinical academic training and unstructured academic training. Life as an academic consultant is also described. Funding is explored, for the specialty as a whole and at the individual level. UK academic neurosurgical organisations are highlighted. Finally, the UK’s international standing is considered.


1995 ◽  
Vol 9 (6) ◽  
pp. 1329-1339 ◽  
Author(s):  
Daniel M. Green ◽  
Max J. Coppes

2010 ◽  
Vol 06 ◽  
pp. 53
Author(s):  
Arlene A Gayle ◽  
Noelle K LoConte ◽  
◽  

Pancreatic adenocarcinoma is common among older adults, who may be more frail or have comorbid medical conditions that make treatment more challenging. Pancreatic adenocarcinoma is a lethal malignancy with relatively few effective treatment options. To date, most clinical research has not enrolled large numbers of older adults, despite this being the demographic predominantly affected by this illness. In this article, etiology and treatments for pancreatic adenocarcinoma are reviewed with a particular emphasis on studies that have examined matters relating to treating older adults; future directions for research are also explored.


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