The Synergistic Antibacterial Effect of Azadirachta indica Leaves Extract and Aloe barbadensis Gel Against Bacteria Associated with Skin Infection

2018 ◽  
pp. 581-591
Author(s):  
Hamidah Jaafar Sidek ◽  
Mohamad Azhar Azman ◽  
Muhamad Shafizul Md Sharudin
Keyword(s):  
Azadirachta Indica ◽  
Skin Infection ◽  
Antibacterial Effect ◽  
Aloe Barbadensis

scholarly journals The antibacterial effect of topical ozone on the treatment of MRSA skin infection

2017 ◽  
Author(s):  
Mingsheng Song ◽  
Qinghai Zeng ◽  
Yaping Xiang ◽  
Lihua Gao ◽  
Jian Huang ◽  
...  
Keyword(s):  
Skin Infection ◽  
Antibacterial Effect

scholarly journals Antibacterial and Cytotoxic Effects of Moringa oleifera (Moringa) and Azadirachta indica (Neem) Methanolic Extracts against Strains of Enterococcus faecalis

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Lucía Arévalo-Híjar ◽  
Miguel Ángel Aguilar-Luis ◽  
Stefany Caballero-García ◽  
Néstor Gonzáles-Soto ◽  
Juana Del Valle-Mendoza
Keyword(s):  
Enterococcus Faecalis ◽  
Azadirachta Indica ◽  
Moringa Oleifera ◽  
Antibacterial Effect ◽  
Methanolic Extract ◽  
Inhibition Zone ◽  
Bactericidal Effect ◽  
Growth Inhibition Zone ◽  
Methanolic Extracts

Objective. To evaluate antibacterial and cytotoxic effect of 2 methanolic extracts of Azadirachta indica and Moringa oleifera against strains of Enterococcus faecalis (ATCC 29212) in vitro. Methods. The methanolic extracts of Azadirachta indica and Moringa oleifera were prepared in vitro. The antibacterial effect of the extracts against Enterococcus faecalis was evaluated using the agar diffusion technique. The minimum inhibitory concentration (MIC) was determined using the microdilution method and the cytotoxicity using the cellular line MDCK. Results. The methanolic extract with the most antibacterial effect during the first 24 and 48 hours against Enterococcus faecalis was Moringa oleifera, evidencing a growth inhibition zone of 35.5 ± 1.05 and 44.83 ± 0.98, respectively. The MIC for both extracts was 75 µg/ml. The bactericidal effect of the Azadirachta indica extract was found at a concentration of 25 µg/ml and a concentration of 75 µg/ml for Moringa extract. Conclusions. In conclusion, we demonstrated that the methanolic extract of Azadirachta indica and Moringa oleifera both have an antibacterial effect against Enterococcus faecalis strains during the first 24 and 48 hours. None of the extracts exhibited toxicity against the cell lines under low concentrations.

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