scholarly journals Synergistic activity of cold pressed seed oils from Indian neem (Azadirachta indica), karanja (Pongamia glabra) and aloe vera gel (Aloe barbadensis) in a cosmeceutical moisturizer

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
RF Oliveira ◽  
L Barreiro ◽  
A Cruz ◽  
AI Oliveira ◽  
A Dias ◽  
...  
2020 ◽  
Vol 13 (11) ◽  
pp. 2371-2380
Author(s):  
Ahmed Kamr ◽  
Ali Arbaga ◽  
Amanallah El-Bahrawy ◽  
Ahmed Elsify ◽  
Hadeer Khaled ◽  
...  

Background and Aim: Staphylococcus pyoderma is a common problem in dogs that need a novel treatment rather than antibiotic therapy. The aim of this study was to investigate the therapeutic efficacy, anti-inflammatory, and antioxidative properties of Aloe vera (Aloe barbadensis) gel ointment on dogs' Staphylococcus pyoderma compared to gentamicin ointment. Materials and Methods: The inhibition zone of A. vera extract 20% and 40% and gentamicin 1% against Staphylococcus aureus was determined on well diffusion agar. Twenty Baladi local breed dogs were used as control negative group before intradermal inoculation with 105 CFU S. aureus. The animals were classified into four equal groups, control positive group without treatment (n=5), treated groups by 20% A. vera gel ointment (n=5), 40% A. vera gel ointment (n=5), and gentamicin ointment 1% (n=5). Topical application of A. vera and gentamicin ointments was carried out twice daily for 2 weeks until complete healing of dogs' pyoderma. Clinical evaluation was recorded. Inflammatory, oxidant, and antioxidant parameters were measured in serum. Results: The inhibition zone of A. vera extracts 20% and 40% was 19 mm and 23 mm, respectively, while gentamicin 1% was 18 mm. The half maximal inhibitory concentration (of A. vera 20% and 40% were 13.70 with R2=0.98. Dogs' pyoderma treated with A. vera gel ointment 20% and 40% were more likely to have low haptoglobin and tumor necrosis factor-α concentrations than gentamicin 1% ([odds ratio [OR]=4.6; 95% confidence interval [CI]=1.31-17.40; p<0.05]; [OR=5.2; 95% CI=1.04-22.30; p<0.05]), respectively. Conclusion: It seems evident that A. vera has therapeutic effect, antibacterial, and anti-inflammatory effects against dogs' staphylococcal pyoderma than gentamicin that would support its further use rather than antibiotics in one health arena.


2016 ◽  
Vol 44 (2) ◽  
pp. 61-66
Author(s):  
Shammin Haque ◽  
Ferdous Ara ◽  
Md Jalaluddin Iqbal ◽  
Sheikh Nazrul Islam

This study was conducted to evaluate the effect of different extracts of Aloe Vera gel in alloxan induced hyperglycaemic mice.Three different extracts of Aloe Vera gel (dried extract, ethanolic extract and fresh raw extract) were orally administered at 300 mg/kg body weight for 28 days. The fasting blood glucose level was estimated both in normal and alloxan induced hyperglycaemic mice. It was found that, when compared with the control, there was a significant reduction in blood glucose level in all three experimental groups. Ethanolic and fresh raw gel extracts were more effective than the dried extract. The extracts produced similar results when compared with gliclazide. It can be concluded that, the administration of Aloe Vera gel extract significantly decreases blood glucose level in hyperglycaemic mice. Aloe Vera gel can therefore be a natural remedy and a cost effective resource for the management of diabetes.Bangladesh Med J. 2015 May; 44 (2): 61-66


2011 ◽  
Vol 129 (3) ◽  
pp. 1060-1065 ◽  
Author(s):  
Antonio Vega-Gálvez ◽  
Margarita Miranda ◽  
Mario Aranda ◽  
Karem Henriquez ◽  
Judith Vergara ◽  
...  

Author(s):  
NIKHIL NITIN NAVINDGIKAR ◽  
K. A. KAMALAPURKAR ◽  
PRASHANT S. CHAVAN

Objective: To formulate and evaluate herbal cream using Aloe Vera gel, dimethyl sulphoxide extracts of Neem (Azadirachta indica) and Tulsi (Ocimumtenuiflorum) to give multipurpose effect. Methods: The cream was prepared by using the cream base that is bee’s wax, liquid paraffin, borax, methylparaben, distilled water, rose oil, Aloe Vera gel, dimethyl sulphoxide extracts of Neem and Tulsi. The cream was prepared by using the slab technique/extemporaneous method for geometric and homogenous mixing of all the excipients and the herbal extracts. By using slab technique, we have developed three batches of our herbal cream, namely F1H, F2H, and F3H. All three batches were evaluated for different parameters like appearance, PH, viscosity, phase separation. Results: All the three formulations F1H, F2H, F3H showed good appearance, PH, adequate viscosity and no phase separation was observed. Also, the formulations F1H, F2H, F3H showed no redness, erythema and irritation during irritancy study and they were easily washable. All the three formulations F1H, F2H, F3H were stable at room temperature. Conclusion: All three herbal ingredients showed significant different activities. Based on the results, we can suggest that all the three formulations F1H, F2H, F3H were stable and can be safely used on the skin.


2019 ◽  
Vol 36 (1-2) ◽  
pp. 25-32
Author(s):  
MM Islam ◽  
KKI Khalil ◽  
MA Islam ◽  
KM Sujan ◽  
A Mustari ◽  
...  

The study was designed to assess the effects of aloe vera gel (AVG) on broiler growth performance and haemato-biochemical changes. “Lohman” day-old broiler chicks (n=48) were reared for 28 days. At day 13, chicks were randomly divided into four equal groups (12/group). Group A was non-treated control. Group B was supplemented with antibiotic (oxytetracycline hydrochloride) as a growth promoter in water. Group C and D were supplied AVG (1% and 2%) in drinking water. Antibiotic and AVG treated broilers had higher (P<0.05) live weight (1803.8 ± 63.6 gm and 1800.00 ± 64.2 gm) than control (1607.5 ± 41.7 gm). Total erythrocyte count (3.6 ± 0.1 x 106/uL), haemoglobin (9.9 ± 0.1 gm%) and packed cell volume (35.2 ± 0.4 %) were higher (P<0.05) in treated groups. It is suggested that the aloe vera gel supplementation (1-2%) may be used as an alternative to antibiotics for better growth performance in broilers without deleterious effects on haematobiochemical profiles. The Bangladesh Veterinarian (2019) 36(1 - 2): 25-32


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