Biogenic Silver Nanoparticles: A Potent Therapeutic Agent

2021 ◽  
pp. 81-127
Author(s):  
Shakil Ahmed Polash ◽  
Md. Monir Hossain ◽  
Tanushree Saha ◽  
Satya Ranjan Sarker
2019 ◽  
Vol 25 (35) ◽  
pp. 3740-3750 ◽  
Author(s):  
Ning Sun ◽  
Dongli Li ◽  
Xiaoqing Chen ◽  
Panpan Wu ◽  
Yu-Jing Lu ◽  
...  

Oleanolic acid is an analogue of pentacyclic triterpenoids. It has been used as a hepatic drug for over 20 years in China. Currently, there are only five approved drugs derived from pentacyclic triterpenoids, including oleanolic acid (liver diseases), asiaticoside (wound healing), glycyrrhizinate (liver diseases), isoglycyrrhizinate (liver disease) and sodium aescinate (hydrocephalus). To understand more about the bioactivity and functional mechanisms of oleanolic acid, it can be developed as a potent therapeutic agent, in particular, for the prevention and treatment of heart diseases that are the leading cause of death for people worldwide. The primary aim of this mini-review is to summarize the new applications of oleanolic acid and its derivatives as cardioprotective agents reported in recent years and to highlight their therapeutic perspectives in cardiovascular diseases.


2016 ◽  
Vol 205 (6) ◽  
pp. 603-613 ◽  
Author(s):  
M. Składanowski ◽  
P. Golinska ◽  
K. Rudnicka ◽  
H. Dahm ◽  
M. Rai

2021 ◽  
Vol 297 ◽  
pp. 113434
Author(s):  
Federico N. Spagnoletti ◽  
Florencia Kronberg ◽  
Cecilia Spedalieri ◽  
Eliana Munarriz ◽  
Romina Giacometti

2017 ◽  
Vol 8 (9) ◽  
pp. e3050-e3050 ◽  
Author(s):  
Xinhua Xiao ◽  
Huiliang Li ◽  
Huizi Jin ◽  
Jin Jin ◽  
Miao Yu ◽  
...  

2021 ◽  
Vol 17 ◽  
Author(s):  
Amita Sahu ◽  
Sudhanshu Shekhar Swain ◽  
Goutam Ghosh ◽  
Deepak Pradhan ◽  
Dipak Kumar Sahu ◽  
...  

Background: Literature evidences as well as traditional uses of genus Alphonsea reveal significant antimicrobial and anti-oxidant activity, which encourages to consider A. madraspatana to have potent antimicrobials, there by offering potential adjuncts to synthesize improved antimicrobial Silver nanoparticles (AgNPs). The objective of the present exposition is to optimize reaction parameters to synthesize antimicrobial Biogenic Silver nanoparticles (BAgNPs) from extract of A. madraspatana leaves (AML) and to evaluate the effect against bacteria. Methods: BAgNPs was synthesized by optimized reaction. The Synthesized nanoparticles were characterized by UV, IR, ICP-MS and XRD analysis. The antibacterial potency of optimized BAgNPs was evaluated against E. coli by comparing with positive controls. Results: Results of optimization process indicate nanoscale BAgNPs were produced at operating temp. of 45°C for 120 min at pH 8 with 1:5 volume ratio of AgNO3 and extract. Optimized BAgNPs exhibits relatively higher antimicrobial activity (31±1mm) compared to Ciprofloxacin (27±1mm) and marketed nano silver (28± 2 mm). The developed BAgNPs shows comparable biofilm inhibition (86.50%) as compared to marketed nano silver (88.10%) and Ciprofloxacin (83.10%). Conclusion: Experimental evidence suggests methanolic extract of AML under predefined conditions successfully generate nano-template of silver with better antibacterial response against E. coli.


Sign in / Sign up

Export Citation Format

Share Document