Drugs Affecting Renal Excretory Function

2021 ◽  
pp. 393-409
Author(s):  
Abialbon Paul
Keyword(s):  
Excretory Function ◽  
Renal Excretory Function

Acute Effects of Acetazolamide (Diamox) on Plasma and Urinary Electrolytes of Dogs With Special Reference to Calcium

1957 ◽  
Vol 191 (2) ◽  
pp. 388-392 ◽  
Author(s):  
Smith Freeman ◽  
Anne B. Jacobsen
Keyword(s):  
Carbon Dioxide ◽  
Plasma Concentration ◽  
Chloride Concentration ◽  
Total Plasma ◽  
Acute Effects ◽  
Plasma Phosphate ◽  
Sodium Potassium ◽  
Excretory Function ◽  
Acute Increase ◽  
Renal Excretory Function

Administration of Diamox by ingestion or injection to adult fasting female dogs consistently produced an acute increase of approximately 1 mg % in the plasma concentration of calcium. At the same time there was an increase in the plasma phosphate and chloride concentration and a decrease in total plasma content of carbon dioxide of Diamox-infused dogs. Diamox did not affect the plasma concentration of calcium, chloride or bicarbonate if renal excretory function was abolished prior to its administration. Infusion of Diamox produced a prompt rise in the urinary excretion of sodium, potassium, calcium, phosphate, citrate, chloride and water in fasting female dogs. The effect of Diamox on the fasting concentration of calcium rendered unsatisfactory the interpretation of data concerned with a study of its effect on the disappearance of injected calcium. However, intravenous injection of small amounts of sodium carbonate was found to produce a definite delay in the rate of disappearance of injected calcium.

Abstract 067: Mechanism of Action of 8-Aminoguanine on Renal Excretory Function

Hypertension ◽  
2018 ◽  
Vol 72 (Suppl_1) ◽  
Author(s):  
Edwin K Jackson ◽  
Zaichuan Mi ◽  
Thomas R Kleyman ◽  
Dongmei Cheng
Keyword(s):  
Mechanism Of Action ◽  
Excretory Function ◽  
Renal Excretory Function

scholarly journals STUDIES ON EXPERIMENTAL HYPERTENSION

1941 ◽  
Vol 73 (3) ◽  
pp. 439-451 ◽  
Author(s):  
Harry Goldblatt ◽  
Harry Weinstein ◽  
Joseph R. Kahn
Keyword(s):  
Blood Pressure ◽  
Renal Artery ◽  
Arterial Occlusion ◽  
Experimental Hypertension ◽  
Excretory Function ◽  
Main Renal Artery ◽  
Significant Impairment ◽  
Temporary Occlusion ◽  
Renal Origin ◽  
Renal Excretory Function

By means of a silver chain attached to a silver ring around the main renal artery, intermittent renal arterial occlusion, up to 30 minutes daily, was practiced for as long as 5 months in unilaterally nephrectomized dogs. This did not result in the development of persistently elevated blood pressure. Persistent moderate constriction of the renal artery of such animals by a silver clamp, after intermittent temporary occlusion had failed to affect the blood pressure, produced the usual rise of blood pressure, without accompanying significant impairment of renal excretory function. When the renal artery accidentally became persistently constricted to a great degree, or actually occluded, or if occlusion was deliberately produced by continuous pulling of the chain, hypertension and renal insufficiency (the malignant phase) quickly developed. The results do not lend support to the view that brief daily periods of renal ischemia from intrarenal vasospasm, or from any other cause, can produce persistent hypertension of renal origin.

Morphometric correlates of renal excretory function

1990 ◽  
Vol 160 (3) ◽  
pp. 245-253 ◽  
Author(s):  
A. J. Howie ◽  
B. K. Gunson ◽  
J. Sparke
Keyword(s):  
Excretory Function ◽  
Renal Excretory Function
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