scholarly journals Presence of very low density lipoprotein compositional abnormalities in Type 1 (insulin-dependent) diabetic patients; effects of blood glucose optimisation

Diabetologia ◽  
1988 ◽  
Vol 31 (12) ◽  
Author(s):  
A. Rivellese ◽  
G. Riccardi ◽  
G. Romano ◽  
R. Giacco ◽  
L. Patti ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Diabetic Patients ◽  
Very Low Density Lipoprotein ◽  
Low Density ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic

Abnormal composition of apoproteins C-I, C-II, and C-III in plasma and very-low-density lipoproteins of non-insulin-dependent diabetic Chinese.

1986 ◽  
Vol 32 (10) ◽  
pp. 1914-1920 ◽  
Author(s):  
X R Pan ◽  
M C Cheung ◽  
C E Walden ◽  
S X Hu ◽  
E L Bierman ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Diabetic Patients ◽  
Low Density ◽  
Strongly Correlated ◽  
Very Low Density Lipoproteins ◽  
White American ◽  
Insulin Dependent ◽  
L Value ◽  
Insulin Dependent Diabetic

Abstract Apoprotein (apo) C-I, C-II, and C-III were measured in plasma from 35 white American non-diabetic subjects. The mean concentrations (mg/L) in plasma from normolipidemic and hypertriglyceridemic subjects, respectively, were apo C-I, 78 and 311; apo C-II, 37 and 200; and apo C-III, 98 and 529. These concentrations were strongly correlated with the concentrations of plasma triglyceride (TG). We also measured these apoproteins in 23 Chinese non-insulin-dependent diabetic patients (13 men, 10 women) and in eight male and 10 female non-diabetic Chinese controls. The male diabetics had significantly lower concentrations of apo C-I in plasma, and lower apo C-I/TG, apo C-II/TG, apo C-III/TG, and apo C-I/C-III ratios than did the controls. The female diabetics had significantly higher apo C-II concentrations than the controls. The median value for plasma glucose during fasting was 1400 mg/L in the male diabetic subjects, similar to the 1370 mg/L value in female diabetics. Therefore, the higher concentrations of very-low-density lipoprotein in male diabetics may not reflect hyperglycemia per se.

scholarly journals Influence of Low Density Lipoprotein from Insulin-Dependent Diabetic Patients on Platelet Functions

1999 ◽  
Vol 84 (10) ◽  
pp. 3770-3774 ◽  
Author(s):  
R. A. Rabini ◽  
R. Staffolani ◽  
D. Martarelli ◽  
P. Fumelli ◽  
F. Ravaglia ◽  
...  
Keyword(s):  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Diabetic Patients ◽  
Low Density ◽  
Insulin Dependent ◽  
Insulin Dependent Diabetic ◽  
Platelet Functions

scholarly journals Evaluation of type-2 diabetes mellitus patients for dyslipidemia in a tertiary care centre

2020 ◽  
Vol 7 (4) ◽  
pp. 586
Author(s):  
Janak G. Chokshi ◽  
Apal P. Gandhi ◽  
Ishvarlal M. Parmar ◽  
Dipen R. Damor
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Total Cholesterol ◽  
Plasma Glucose ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Diabetic Patients ◽  
Low Density ◽  
Increased Risk

Background: Diabetes mellitus (DM) is a syndrome consisting of metabolic, vascular and neuropathic components that are interrelated. Diabetes mellitus is associated with a considerably increased risk of premature atherosclerosis, particularly coronary heart disease (CHD) and peripheral arterial disease. Dyslipidemia is a common feature of diabetes. There is an association between atherosclerotic cardiovascular disease and serum cholesterol and triglyceride levels in both type 1 and type 2 diabetes.Methods: The study was done on 50 adult diabetes mellitus (T2) patients from IPD of General Medicine wards at SMS Hospital, Ahmedabad, Gujarat. 50 healthy age and sex matched healthy volunteers were taken as control. They were evaluated for lipid profile i.e., Total Cholesterol (TC),Triglyceride (TG), Low-density lipoprotein (LDL), High density lipoprotein (HDL), Very low density lipoprotein (VLDL) and glycemic status i.e., Fasting blood glucose (FBS), Postprandial 2 hours blood glucose (PP2BS) & Glycosylated haemoglobin(HbA1C).Results: Diabetic cases had statistically highly significant (p<0.001) elevated levels of total Cholesterol, Triglycerides and VLDL as compared to controls. Serum TG, serum TC, LDL-C and VLDL-C had positive correlation with the postprandial plasma glucose, fasting plasma glucose and HbA1c.Conclusions: Significant correlations between HbA1c levels and lipid levels point towards the usefulness of HbA1c for screening high-risk diabetic patients. High TC, TG, LDL-C and HbA1c with normal or low HDL-C is seen in almost all diabetic patients either alone or in combinations.

scholarly journals Very Low Density Lipoprotein–Mediated Signal Transduction and Plasminogen Activator Inhibitor Type 1 in Cultured HepG2 Cells

1999 ◽  
Vol 85 (2) ◽  
pp. 208-217 ◽  
Author(s):  
Cristina Banfi ◽  
Luciana Mussoni ◽  
Patrizia Risé ◽  
Maria Grazia Cattaneo ◽  
Lucia Vicentini ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Plasminogen Activator Inhibitor ◽  
Very Low Density Lipoprotein ◽  
Low Density ◽  
Inhibitor Type ◽  
Activator Inhibitor Type ◽  
Activator Inhibitor

In vitro degradation of very low density lipoprotein from diabetic patients by lipoprotein lipase

1993 ◽  
Vol 217 (2) ◽  
pp. 105-114 ◽  
Author(s):  
S. Saheki ◽  
Y. Hitsumoto ◽  
M. Murase ◽  
N. Takeuchi ◽  
K. Uchida
Keyword(s):  
Lipoprotein Lipase ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Diabetic Patients ◽  
Very Low Density Lipoprotein ◽  
Low Density ◽  
In Vitro Degradation
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