The effects of exposure to exogenous fatty acids and membrane fatty acid modification on the electrical properties of NG108-15 cells

1985 ◽  
Vol 5 (4) ◽  
pp. 333-352 ◽  
Author(s):  
Jeffrey A. Love ◽  
William R. Saum ◽  
Richard McGee
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Electrical Properties ◽  
Membrane Fatty Acid ◽  
Acid Modification ◽  
Fatty Acid Modification

Effects on Physicochemical Characteristics of Yoghurt and Ice Cream with Fatty Acid Modification and Cholesterol Removal

2015 ◽  
Vol 58 (1) ◽  
pp. 40-46
Author(s):  
Muhammad Nadeem ◽  
Rahman Ullah ◽  
Muhammad Imran ◽  
Atta Muhammad Arif
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Milk Fat ◽  
Unsaturated Fatty Acids ◽  
Ice Cream ◽  
Physicochemical Characteristics ◽  
Tocopherol Content ◽  
Acid Modification ◽  
Cholesterol Removal ◽  
Fatty Acid Modification

This study investigated the effect of fatty acid modification and cholesterol removal on physico-chemical characteristics of yoghurt and ice cream. Fatty acid profile of milk fat was modified by feeding calcium salts of soybean oil fatty acids to cows and cholesterol was removed by b-cyclodextrin. b-cyclodextrin removed 76% and 60% cholesterol from yoghurt and ice cream. Modification of fatty acid composition did not have a significant effect on a-tocopherol content; while b-cyclodextrin treated milk had substantially lower a-tocopherol content. The concentration of a-tocopherol in control and b-cyclodextrin treated yoghurt was 45.62, 32.73 mg/g and 210.34, 185.56 mg/g for ice cream, respectively. Fatty acid modification and cholesterol removal significantly decreased the overrun in ice cream (P<0.05), with no effect on sensory characteristics of yoghurt and ice cream. These results evidenced that milk with higher content of unsaturated fatty acids and low cholesterol can be used in the formulation of yoghurt and ice cream with improved health benefits and suitable sensory features.

Membrane fatty acid modification in tumor cells: A potential therapeutic adjunct

Lipids ◽  
1987 ◽  
Vol 22 (3) ◽  
pp. 178-184 ◽  
Author(s):  
C. Patrick Burns ◽  
Arthur A. Spector
Keyword(s):  
Fatty Acid ◽  
Tumor Cells ◽  
Membrane Fatty Acid ◽  
Acid Modification ◽  
Fatty Acid Modification

scholarly journals 5-Octadecenoic acid: evidence for a novel type of fatty acid modification in schistosomes

1998 ◽  
Vol 334 (2) ◽  
pp. 315-319 ◽  
Author(s):  
Jos F. H. M. BROUWERS ◽  
Cornelis VERSLUIS ◽  
Lambert M. G. van GOLDE ◽  
Aloysius G. M. TIELENS
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Outer Membrane ◽  
De Novo ◽  
Octadecenoic Acid ◽  
Chain Elongation ◽  
Acid Modification ◽  
Fatty Acid Modification ◽  
Membrane Complex ◽  
Specific Localization

The lipid metabolism of schistosomes is characterized by several intriguing adaptations to a parasitic way of living. The surface of the parasite consists of two closely apposed phospholipid bilayers, a structure unique to blood flukes. Schistosomes do not synthesize fatty acids de novo, but are able to modify fatty acids, which they obtain from the host, by chain elongation. Here we present evidence that schistosomes are capable of another type of fatty acid modification, resulting in the formation of 5-octadecenoic acid [C18:1(5)]. This highly unusual fatty acid, which is absent in the blood of the host, was shown to be almost exclusively located in the outer membrane complex of the schistosome. Within these membranes, it was almost exclusively present in one molecular phospholipid species, 1-palmitoyl-2,5-octadecenoyl phosphatidylcholine [C16:0–18:1(5)PtdCho]. Apart from dipalmitoyl phosphatidylcholine, this was the most abundant phosphatidylcholine species in the outer membrane complex. The specific synthesis by the schistosome of C18:1(5) and the highly specific localization of this fatty acid to the tegumental membranes suggest an important tegument-mediated role for this lipid.

scholarly journals Effects of Conjugated Linoleic Acid. 1. Fatty Acid Modification of Yolks and Neonatal Fatty Acid Metabolism

2000 ◽  
Vol 79 (6) ◽  
pp. 817-821 ◽  
Author(s):  
M.A. Latour ◽  
A.A. Devitt ◽  
R.A. Meunier ◽  
J.J. Stewart ◽  
B.A. Watkins
Keyword(s):  
Fatty Acid ◽  
Linoleic Acid ◽  
Conjugated Linoleic Acid ◽  
Fatty Acid Metabolism ◽  
Acid Metabolism ◽  
Acid Modification ◽  
Fatty Acid Modification

scholarly journals Ankyrin-bound fatty acid turns over rapidly at the erythrocyte plasma membrane.

1987 ◽  
Vol 7 (8) ◽  
pp. 2981-2984 ◽  
Author(s):  
M Staufenbiel
Keyword(s):  
Fatty Acids ◽  
Plasma Membrane ◽  
Fatty Acid ◽  
Long Chain Fatty Acids ◽  
Acid Modification ◽  
Skeletal Protein ◽  
Erythrocyte Plasma Membrane ◽  
Polypeptide Backbone ◽  
Long Chain ◽  
Regulatory Significance

The membrane skeletal protein ankyrin was shown to be continuously acylated and deacylated with long-chain fatty acids in mature erythrocytes. At least a fraction of the lipid bound to ankyrin turned over rapidly (half-life, approximately 50 min) compared with the polypeptide backbone, which was stable throughout the erythrocyte life. This indicates a regulatory significance of the fatty acid modification for the function of ankyrin.

scholarly journals Lactobacillus paracasei A13 and High-Pressure Homogenization Stress Response

2020 ◽  
Vol 8 (3) ◽  
pp. 439 ◽  
Author(s):  
Lorenzo Siroli ◽  
Giacomo Braschi ◽  
Samantha Rossi ◽  
Davide Gottardi ◽  
Francesca Patrignani ◽  
...  
Keyword(s):  
Fatty Acids ◽  
High Pressure ◽  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Membrane Fluidity ◽  
Acid Composition ◽  
Lactobacillus Paracasei ◽  
High Pressure Homogenization ◽  
Membrane Fatty Acid ◽  
Membrane Fatty Acid Composition

Sub-lethal high-pressure homogenization treatments applied to Lactobacillus paracasei A13 demonstrated to be a useful strategy to enhance technological and functional properties without detrimental effects on the viability of this strain. Modification of membrane fatty acid composition is reported to be the main regulatory mechanisms adopted by probiotic lactobacilli to counteract high-pressure stress. This work is aimed to clarify and understand the relationship between the modification of membrane fatty acid composition and the expression of genes involved in fatty acid biosynthesis in Lactobacillus paracasei A13, before and after the application of different sub-lethal hyperbaric treatments. Our results showed that Lactobacillus paracasei A13 activated a series of reactions aimed to control and stabilize membrane fluidity in response to high-pressure homogenization treatments. In fact, the production of cyclic fatty acids was counterbalanced by the unsaturation and elongation of fatty acids. The gene expression data indicate an up-regulation of the genes accA, accC, fabD, fabH and fabZ after high-pressure homogenization treatment at 150 and 200 MPa, and of fabK and fabZ after a treatment at 200 MPa suggesting this regulation of the genes involved in fatty acids biosynthesis as an immediate response mechanism adopted by Lactobacillus paracasei A13 to high-pressure homogenization treatments to balance the membrane fluidity. Although further studies should be performed to clarify the modulation of phospholipids and glycoproteins biosynthesis since they play a crucial role in the functional properties of the probiotic strains, this study represents an important step towards understanding the response mechanisms of Lactobacillus paracasei A13 to sub-lethal high-pressure homogenization treatments.

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