Structural and metabolic changes in the brain of animals with disturbances of higher nervous activity following repeated administration of chlorpromazine

1964 ◽  
Vol 58 (3) ◽  
pp. 1085-1090 ◽  
Author(s):  
M. M. Aleksandrovskaya ◽  
Yu. Ya. Geinisman ◽  
L. G. Samoilova
Keyword(s):  
Nervous Activity ◽  
Repeated Administration ◽  
Metabolic Changes ◽  
Higher Nervous Activity ◽  
The Brain

Pavlov's Position on Old Age within the Framework of the Theory of the Higher Nervous Activity

1995 ◽  
Vol 40 (2) ◽  
pp. 89-102 ◽  
Author(s):  
George Windholz
Keyword(s):  
Old Age ◽  
Nervous Activity ◽  
Psychiatric Clinic ◽  
General Process ◽  
Conditioned Reflexes ◽  
Neural Processes ◽  
Higher Nervous Activity ◽  
Theory Of Aging ◽  
Per Se ◽  
The Brain

In the 1920s, as I. P. Pavlov was growing old, he began to show interest in the general process of aging. In order to study senescence, Pavlov and his disciples experimented in the laboratory on old dogs by the method of salivary conditioning and also observed aged psychotic patients in the psychiatric clinic. Pavlov never formulated a theory of aging per se, but incorporated his findings on aging into his theory of higher nervous activity, which dealt with the function of the brain in higher organisms' adaptation to the environment. Some of the major findings showed that salivary conditioning and stimulus differentiation were difficult to establish in old dogs. Conditioned reflexes established earlier in dogs' lives, however, persisted into old age. Pavlov explained these findings in terms of hypothesized neural processes in the brain; with age, neural processes deteriorate and their reactivity to the environment wanes. In light of more recent research, Pavlov's views on senescence, with the exception of the relation of conditioning to aging, are mainly of historical interest.

scholarly journals Genius Ideas and Genius Mistakes. (Non-material Nature of the Psyche, Part II)

2019 ◽  
pp. 36-41
Author(s):  
M. M. Reshetnikov
Keyword(s):  
Social Sciences ◽  
Mental Disorders ◽  
Nervous Activity ◽  
Signal System ◽  
Higher Nervous Activity ◽  
The Brain

The author develops ideas, which he presented in his paper Critical rethinking of the use of pharmacotherapy in mental disorders and critically analyses works by Descartes, I.М. Sechenov and I.P. Pavlov, which determined our methods of studying the psyche and treating mental disorders for many centuries. Reflexes of the Brain by I.M. Sechenov and ideas of the second signal system and higher nervous activity by I.P. Pavlov are analysed in detail. The author proves that these ideas, which still influence development of psychology, psychiatry, psychotherapy and social sciences, are fallacious.

scholarly journals General Theory of Intelligence

2021 ◽  
Author(s):  
Valentyn Shcherbak
Keyword(s):  
General Theory ◽  
Physical Properties ◽  
Nervous Activity ◽  
Structure Functions ◽  
Theory Of Intelligence ◽  
Higher Nervous Activity ◽  
The Brain ◽  
The Universe

In this paper, the dependence of the properties of the brain, its structure, functions and the higher nervous activity derived from them on the physical properties of the universe is analyzed.

scholarly journals Features of monocytes dynamics amount in blood of pigs with different types of higher nervous activity

2018 ◽  
Vol 20 (83) ◽  
pp. 274-278
Author(s):  
V.O. Trokoz ◽  
A.V. Trokoz
Keyword(s):  
Nervous System ◽  
Weak Type ◽  
Nervous Activity ◽  
Repeated Administration ◽  
Immunological Reactivity ◽  
Specific Immunity ◽  
Higher Nervous Activity ◽  
Different Types ◽  
Wbc Count ◽  
Research Period

The aim of this research was to figure out the level and character of typological nervous system features influence on immunological reactivity manifestation in pigs, in particularly dynamics of monocytes count in plasma under the influence of biological stimulation (vaccination against Swine Reproductive and Respiratory Syndrome). Swine groups of Strong Balanced Agile, Strong Balanced Inert, Strong Unbalanced and Weak types of higher nervous activity were formed for te experiment. Within the research period WBC count was performed for blood of these animals (in Goryaev`s camera), particularly relative monocytes count was determined along with calculation of absolute figure of monocyte contents. It was investigated that the smallest relative monocytes amount is characteristic for pigs of Weak type of higher nervous system. It might be the evidence that the animals with Strong Balanced Agile type of higher nervous activity possess much more potent non-specific immunity, on the other hand animals of Weak type – the poorest. The strongest straight correlation of relative monocytes amount was investigated to force of cortical processes. Nevertheless, participation in regulation of monocytes content in blood of pigs with different types of higher nervous activity also have taken agility and balance of excitation and inhibition processes. Biological stimuli influence is strengthens mentioned connections, but most of all with force of cortical processes. Repeated biological stimuli sharply lower the correlation of the relative monocytes amount to other properties of excitation and inhibition processes in cerebral hemispheres cortex. Further, relationships are renewed and in 28th day after repeated administration of antigen to animals coefficients of correlation are close to initial ones, especially towards cortical processes` force. This certifies that animals of Strong Balanced Agile type of higher nervous activity firstly react non-specifically on biological stimuli, and those reactions is strong enough to protect them against damaging factor. For animals with Weak type such reaction is not typical. That is why those animals have to be treated with cautions during veterinary and husbandry performances. Further research in the direction of finding out the features of non-specific immunity in animals of different types of higher nervous activity and the effect on these indicators of autonomic nervous system excitability will be carried out.

Changes in EEG and higher nervous activity of rats receiving acelizine or anti-ischemic protection of the brain

1992 ◽  
Vol 113 (3) ◽  
pp. 312-315
Author(s):  
V. I. Tel'pukhov ◽  
M. V. Bilenko ◽  
A. V. Khokhlov ◽  
P. G. Komarov
Keyword(s):  
Nervous Activity ◽  
Higher Nervous Activity ◽  
The Brain

scholarly journals Scientific and Philosophical Concept of Unity of The Universe

2019 ◽  
Vol 4 (4) ◽  
pp. 01-03
Author(s):  
Vahram R Sargsyan
Keyword(s):  
Nervous Activity ◽  
Genetic Theory ◽  
Philosophical Concept ◽  
Higher Nervous Activity ◽  
Correct Understanding ◽  
The Brain ◽  
The Universe

This paper proposes a new scientific and philosophical concept of the unity of the universe. The concept is based on new biological theories (13 viral theories and one genetic theory) developed in 2018 - 2019 in Yerevan. The issues of materialism, idealism and dualism are discussed. And also the question of the primacy of matter and consciousness is analyzed. This is very important for a correct understanding of the processes occurring in the brain and the formation of the higher nervous activity of a person.

scholarly journals АСИМЕТРІЯ ГОЛОВНОГО МОЗКУ ПРИ АДАПТАЦІЇ ДО УМОВ ВИСОКОГІР'Я

2012 ◽  
Author(s):  
V. I. Portnichenko ◽  
Yu. V. Kravchenko ◽  
O. L. Yevtushenko ◽  
О. М. Bakunovskyi ◽  
І. О. Yachnytsia ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Cortex ◽  
Cerebral Blood Flow ◽  
Initial Period ◽  
Nervous Activity ◽  
Adaptation To Hypoxia ◽  
Brain Blood Flow ◽  
Short Term ◽  
Higher Nervous Activity ◽  
The Brain

Association between cerebral blood flow and higher nervous activity in people at different stages of adaptation to the midlands was studied. Investigation were performed before, during and after a three-week stay in the mountains at an altitude of 2100 m, as well as during short-term ups without the physical load on the height of 3900 m. In the initial period of adaptation to hypoxia desynchronization between the nerve processes in the cerebral cortex and brain blood flow was observed. There was an inversion and an increase in the asymmetry of cerebral blood flow in the direction of the dominance of the left hemisphere of the brain. After the three-week stay in the mountains asymmetry of cerebral blood flow was disappeared, blood flow to the brain was reduced, hemispheric symmetry was formed, and blood flow synchronized with the nerve processes in the cerebral cortex again was restored.

EXPERIMENTAL ASSESSMENT OF THE NANOPARTICLES TOXICITY OF NICKEL OXIDE IN TWO SIZES IN THE SUBCHRONIC EXPERIMENT

2018 ◽  
pp. 30-35
Author(s):  
M.P. Sutunkova ◽  
B.A. Katsnelson ◽  
L.I. Privalova ◽  
S.N. Solovjeva ◽  
V.B. Gurvich ◽  
...  
Keyword(s):  
Nickel Oxide ◽  
Nervous Activity ◽  
Equal Mass ◽  
The Body ◽  
Subchronic Toxicity ◽  
Physiological Mechanisms ◽  
Nickel Oxide Nanoparticles ◽  
The Relationship ◽  
The Brain ◽  
Nanoparticles Toxicity

We conducted a comparative assessment of the nickel oxide nanoparticles toxicity (NiO) of two sizes (11 and 25 nm) according to a number of indicators of the body state after repeated intraperitoneal injections of these particles suspensions. At equal mass doses, NiO nanoparticles have been found to cause various manifestations of systemic subchronic toxicity with a particularly pronounced effect on liver, kidney function, the body’s antioxidant system, lipid metabolism, white and red blood, redox metabolism, spleen damage, and some disorders of nervous activity allegedly related to the possibility of nickel penetration into the brain from the blood. The relationship between the diameter and toxicity of particles is ambiguous, which may be due to differences in toxicokinetics, which is controlled by both physiological mechanisms and direct penetration of nanoparticles through biological barriers and, finally, unequal solubility.

Types of Higher Nervous Activity in Pigs: Characteristics of Behavior and Effects of Technological Stress

2021 ◽  
Author(s):  
O. V. Danchuk ◽  
M. M. Broshkov ◽  
V. I. Karpovsky ◽  
O. M. Bobrytska ◽  
M. I. Tsvivlikhovsky ◽  
...  
Keyword(s):  
Nervous Activity ◽  
Higher Nervous Activity ◽  
Technological Stress
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