Correlative evaluation of serum lipid, blood glucose, blood pressure, serum immunoreactive insulin, and liver function in persons undergoing regularly scheduled health evaluations

1993 ◽  
Vol 17 (3-4) ◽  
pp. 195-199 ◽  
Author(s):  
Y. Nakamura ◽  
S. Katakai ◽  
S. Hayakawa ◽  
S. Kaneko ◽  
K. Ishida
Keyword(s):  
Blood Pressure ◽  
Blood Glucose ◽  
Liver Function ◽  
Serum Lipid ◽  
Immunoreactive Insulin ◽  
Serum Immunoreactive Insulin

scholarly journals Effect of obesity on blood pressure, serum lipid, liver function, blood sugar and uric acid.

1988 ◽  
Vol 43 (5) ◽  
pp. 962-968 ◽  
Author(s):  
Yukio Saito ◽  
Takashi Kato ◽  
Kazushi Okamoto ◽  
Kiyoshi Maeda ◽  
Touru Ohtsuka ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Liver Function ◽  
Blood Sugar ◽  
Serum Lipid

Epicardial fat thickness as arterial hypertension predictor in normotensive patients with abdominal obesity

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Kuznetsova ◽  
M Druzhilov
Keyword(s):  
Blood Pressure ◽  
Regression Analysis ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Arterial Hypertension ◽  
Multivariate Regression ◽  
Fasting Blood Glucose ◽  
Multivariate Regression Analysis ◽  
Epicardial Fat Thickness ◽  
Fat Thickness

Abstract Objective Arterial hypertension (HTN) is one of the most common diseases associated with obesity. Visceral obesity (VO) with dysfunctional visceral adipose tissue plays the main role in obesity induced HTN. Direct criteria of VO including echocardiographic epicardial fat thickness (EFT) may become an additional predictor of HTN. Purpose The aim was to assess the role of echocardiographic EFT (EEFT) as a predictor of HTN in normotensive patients with abdominal obesity (AO). Methods 526 normotensive men (according to ambulatory blood pressure monitoring (ABPM) without therapy) with AO (waist circumference (WC) >94 cm) and SCORE <5%, without cardiovascular diseases and diabetes mellitus were examined (age 45.1±5.0 years). The lipid and glucose profiles, creatinine, uric acid and C-reactive protein blood levels, albuminuria evaluation, echocardiography, carotid ultrasound, bifunctional ABPM were performed. The values of EEFT ≥75 percentile for persons 35–45 years and 46–55 years were 4.8 mm and 5.8 mm respectively. These values used as epicardial VO criteria. Patients with subclinical carotid atherosclerosis due to the lipid-lowering therapy administration (n=98) were excluded from the follow-up. Re-examination with ABPM was conducted on average through 46.3±5.1 months. Data were summarized as mean ± standard error, statistical analysis conducted with paired two-tailed t-tests, Pearson χ2 criterion and multivariate regression analysis. Results Data of 406 persons were available for analysis. HTN as average daily blood pressure ≥130/80 mm Hg was detected in 157 (38.7%) patients. These patients were characterized by initially higher values of age (45.9±4.6 years vs 44.3±4.9 years, p<0.001), waist circumference (106.9±7.3 cm vs 104.2±7.3 cm, p<0.001), body mass index (BMI) (32.0±3.3 kg/m2 vs 30.9±3.2 kg/m2, p<0.001), average daily systolic and diastolic blood pressure (120.7/74.5±4.6/3.4 mm Hg vs 118.2/73.2±5.5/3.9 mm Hg, p<0.001), EEFT (5.2±0.7 mm vs 4.4±1.0 mm, p<0.001). The epicardial VO was initially detected in 95 (23.3%) patients. In patients with HTN the initial prevalence of epicardial VO was greater (58.0% vs 23.3%, p<0.001). As predictors for the multivariate regression analysis the clinical and laboratory examinations data and EEFT were evaluated. According to the results a mathematical model for estimating the probability HTN was obtained: 0.696*fasting blood glucose + 0.198*systolic BP + 2.844*EFT – 40.166 (constant). Among these predictors EEFT was characterized by the highest standardized regression coefficient (0.302, p<0.001) (0.295, p<0.01 for fasting blood glucose, 0.035, p<0.001 for systolic BP). The Hosmer-Lemeshow test value was 0.863, the total percentage of correct classifications was 86%, the area under the ROC-curve was 0.913. Conclusions EEFT (4.8 mm for persons 35–45 years and 5.8 mm for persons 46–55 years) may be an additional predictor of HTN in normotensive patients with AO. Funding Acknowledgement Type of funding source: None

scholarly journals Adverse pregnancy outcomes associated with moderate elevations in blood pressure or blood glucose in Ugandan women; a prospective cohort study

2021 ◽  
Vol 1 (2) ◽  
pp. 100007
Author(s):  
Jack Milln ◽  
Betty Nakabuye ◽  
Barnabas Natamba ◽  
Isaac Sekitoleko ◽  
Michael Mubiru ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cohort Study ◽  
Blood Glucose ◽  
Prospective Cohort Study ◽  
Pregnancy Outcomes ◽  
Prospective Cohort ◽  
Adverse Pregnancy Outcomes ◽  
Adverse Pregnancy

scholarly journals Effects of single and combined gestational phthalate exposure on blood pressure, blood glucose and gestational weight gain: A longitudinal analysis

2021 ◽  
Vol 155 ◽  
pp. 106677
Author(s):  
Hui Gao ◽  
Bei-bei Zhu ◽  
Kun Huang ◽  
Yuan-duo Zhu ◽  
Shuang-qin Yan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Weight Gain ◽  
Blood Glucose ◽  
Gestational Weight Gain ◽  
Longitudinal Analysis ◽  
Gestational Weight ◽  
Phthalate Exposure

scholarly journals Associations of Variability in Metabolic Parameters with Lung Cancer: A Nationwide Population-Based Study

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1982
Author(s):  
In Young Cho ◽  
Kyungdo Han ◽  
Dong Wook Shin ◽  
Mi Hee Cho ◽  
Jung Eun Yoo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Blood Pressure ◽  
Blood Glucose ◽  
Cancer Risk ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Lung Cancer Risk ◽  
Fasting Blood Glucose ◽  
High Variability ◽  
Metabolic Parameters

We investigated whether visit-to-visit variability in metabolic parameters is associated with lung cancer risk. We used nationally representative data from the Korean National Health Insurance System, and 8,011,209 lung-cancer-free subjects who underwent over three health examinations from 2005 to 2010 were followed until 2017. Variability of fasting blood glucose, total cholesterol, systolic blood pressure, and body weight were measured by the variability independent of the mean, assessed by quartiles. There were 44,982 lung cancer events. The hazard ratio (HR) and 95% confidence interval (CI) for lung cancer risk was 1.07 (1.04, 1.10) for fasting blood glucose in the highest quartile, 1.08 (1.05, 1.10) for systolic blood pressure, 1.04 (1.01, 1.07) for weight, and 1.11 (1.08, 1.14) for total cholesterol. When comparing ≥3 vs. 0 high-variability metabolic parameters, the HR for lung cancer was 1.18 (95% CI, 1.14, 1.22). However, while ≥3 high-variability parameters showed an increased lung cancer risk in men (HR 1.26, 95% CI 1.21, 1.31), women did not show increased risk (HR 0.99, 95% CI 0.92, 1.06). High variability in each metabolic parameter, and a higher number of high-variability parameters, were associated with increased lung cancer risk.

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