Isolierung und Identifizierung der Flavon(ol)-O-glykoside in K�mmel (Carum carvi L.), Fenchel (Foeniculum vulgare Mill.), Anis (Pimpinella anisum L.) und Koriander (Coriandrum sativum L.) und von Flavon-C-glykosiden im Anis

1977 ◽  
Vol 164 (3) ◽  
pp. 194-200 ◽  
Author(s):  
Jost Kunzemann ◽  
Karl Herrmann
Author(s):  
Alev ONDER ◽  
Suna Sibel GURPINAR, Mujde ERYILMAZ ◽  
Bayram Kagan AKAY, Ahsen Sevde CINAR

Spices are a part of the plants used for many purposes as preservatives and as colorants in foods or as medicinal intention. Main aim of the present research was to estimate the potential antimicrobial activity of some spices from Apiaceae family such as Amni visnaga (Diş otu, Hıltan), Anethum graveolens (Dereotu), Apium graveolens (Kereviz), Coriandrum sativum (Kişniş), Cuminum cyminum (Kimyon), Daucus carota (Havuç), Foeniculum vulgare (Rezene), Petroselinum sativum (Maydanoz), Pimpinella anisum (Anason). Thus, the fruits of the plants are used in the experiments. The fruits have been extracted by n-hexane, and all extracts have been subjected to TLC (Thin Layer Chromatography). The n-hexane extracts were screened for their potential in vitro antibacterial activity against Staphylococcus aureus ATCC 29213, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 13883, Pseudomonas aeruginosa ATCC 27853 and antifungal activity against Candida albicans ATCC 10231 by microbroth dilution method. The hexane extracts of the fruits of Coriandrum sativum, Anethum graveolens, Daucus carota, and Pimpinella anisum did not show antimicrobial activity against tested microorganisms. Except these, the other extracts having MIC values of 2.5-5-10 mg/mL exhibited antimicrobial effect against some tested microorganisms. These results demonstrate that the extracts which have an antimicrobial effect can probably play a role as an antimicrobial agent owing to their nonpolar components which are accumulated to the n-hexane extracts.


2020 ◽  
Vol 15 (1) ◽  
pp. 511-521 ◽  
Author(s):  
Soňa Felšöciová ◽  
Nenad Vukovic ◽  
Paweł Jeżowski ◽  
Miroslava Kačániová

AbstractPhytopathogenic fungi have been responsible for considerable economic losses in vineyards, and therefore, more attention should be paid to the development and implementation of preventative treatment that is environmentally friendly. The aim of this study was to evaluate the antifungal activity of ten essential oils (EOs) (viz. Lavandula angustifolia Mill., Carum carvi L., Pinus mugo var. pumilio, Mentha piperita L., Foeniculum vulgare L., Pinus sylvestris L., Satureja hortensis L., Origanum vulgare L., Pimpinella anisum L. and Rosmarinus officinalis L.). For the antifungal activity evaluation against Penicillium brevicompactum, P. citrinum, P. crustosum, P. expansum, P. funiculosum, P. glabrum, P. chrysogenum, P. oxalicum, P. polonicum and Talaromyces purpurogenus a disc diffusion method was used. The ten EOs exhibited different antifungal properties. Three tested EOs (Carum carvi L., Satureja hortensis L. and Pimpinella anisum L.) at concentrations of 0.75, 0.50, 0.25 and 0.125 µL/mL showed antifungal activity, inhibiting the mycelial growth. The Origanum vulgare L. EOs exhibited a lower level of inhibition. Overall, Lavandula angustifolia Mill., Pinus mugo var. pumilio, Mentha piperita L., Foeniculum vulgare L., Pinus sylvestris L., Satureja hortensis L., Pimpinella anisum L. and Rosmarinus officinalis L. were effective as fungicidal agents but their efficiency varied between the strains of fungi. Carum carvi L. showed strong antifungal activity against all tested strains at both full strength and reduced concentrations. These EOs could be considered as potential sources of antifungal compounds for treating plant fungal diseases.


2019 ◽  
pp. 1-3
Author(s):  
Alev ONDER ◽  
Suna Sibel GURPINAR, Mujde ERYILMAZ ◽  
Bayram Kagan AKAY, Ahsen Sevde CINAR

Spices are a part of the plants used for many purposes as preservatives and as colorants in foods or as medicinal intention. Main aim of the present research was to estimate the potential antimicrobial activity of some spices from Apiaceae family such as Amni visnaga (Diş otu, Hıltan), Anethum graveolens (Dereotu), Apium graveolens (Kereviz), Coriandrum sativum (Kişniş), Cuminum cyminum (Kimyon), Daucus carota (Havuç), Foeniculum vulgare (Rezene), Petroselinum sativum (Maydanoz), Pimpinella anisum (Anason). Thus, the fruits of the plants are used in the experiments. The fruits have been extracted by n-hexane, and all extracts have been subjected to TLC (Thin Layer Chromatography). The n-hexane extracts were screened for their potential in vitro antibacterial activity against Staphylococcus aureus ATCC 29213, Enterococcus faecalis ATCC 29212, Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 13883, Pseudomonas aeruginosa ATCC 27853 and antifungal activity against Candida albicans ATCC 10231 by microbroth dilution method. The hexane extracts of the fruits of Coriandrum sativum, Anethum graveolens, Daucus carota, and Pimpinella anisum did not show antimicrobial activity against tested microorganisms. Except these, the other extracts having MIC values of 2.5-5-10 mg/mL exhibited antimicrobial effect against some tested microorganisms. These results demonstrate that the extracts which have an antimicrobial effect can probably play a role as an antimicrobial agent owing to their nonpolar components which are accumulated to the n-hexane extracts.


Author(s):  
B. Baranová

Ефірні олії, як вторинні метаболіти рослин, містять широкий спектр біологічно активних сполук, які можуть впливати на метаболічні, біохімічні, фізіологічні та поведінкові функції комах. Метою даного дослідження було оцінити фумігантну і контактну токсичність ефірних масел деяких видів рослин, що використовуються в кулінарії, порівняти ефективність різної дози та часу експозиції, оцінити різницю між відпрацьованими оліями у відсотках смертності, визначити основні сполуки використовуваних ефірних масел. Біоінсектицидну активність ефірних олій анісу (Pimpinella anisum L.), кмину (Carum carvi L.), фенхеля (Foeniculum vulgare Miller) та материнки (Origanum vulgare L.) досліджували на модельних об’єктах. В якості останніх були обрані імаго довгоносика комірного – Sitophilus granarius L. (Coleoptera: Curculionidae) та личинки хрущака борошняного – Tenebrio molitor L. (Coleoptera: Tenebrionidae). З випробуваних ефірних олій, олія з кмину проявила найвищу біоінсектицидну активність. Модельні організмів по різному реагували на вплив еферних олій. Були уражені лише імаго Sitophilus granarius, натомість личинки Tenebrio molitor не реагували на жодний вид олій, які використовували в тестових випробуваннях. З метою заміщення небезпечних токсичних фумігантів та інсектицидів ефірні олії є можливим інструментом захисту сільськогосподарських культур та продуктів харчування від комах-шкідників, як безпечна альтернатива для людини та довкілля, можуть бути використані в сільському господарстві в системі метоідв інтегрованого захисту від комах-шкідників. Однак, ефективність ефірних олій суттєво залежить від цільових груп організмів, а також способу застосування.


Author(s):  
V. M. Odyntsova ◽  
V. H. Korniievska ◽  
M. M. Maletskyi ◽  
Yu. I. Korniievskyi

The family Apiaceae includes 474 genera and 3992–4050 species that are distributed around the globe. Of all the variety of species, our attention was drawn to the raw material of anise – Anisum vulgare Gaertrn.; fennel – Foeniculum vulgare Mill., which contains derivatives of phenylpropane; coriander – Coriandrum sativum L.; dill – Anethum graveolens L.; caraway – Carum carvi L., which is rich in monoterpenoid derivatives. These plants are widely used in medical practice and known to have antimicrobial, antispasmodic, expectorant, antihypertensive, diuretic, choleretic, carminative effects. This versatility is due to the presence of different groups of biologically active substances in the raw materials of plants. The aim of the research is to determine, by means of gas chromatography, a component composition of fruit tinctures of Anisum vulgare Gaertrn., Foeniculum vulgare Mill., Coriandrum sativum L. Anethum graveolens L. and Carum carvi L. Materials and methods. Tinctures were prepared in ratio 1:5 (extractant – 70 % ethyl alcohol) from anise, fennel, coriander, dill, and caraway fruits, which had been harvested in the experimental field of Zaporizhzhia State Medical University in August 2019. Qualitative and quantitative determination of the active compounds was performed using an Agilent 7890B gas chromatograph with a 5977B mass spectrometric detector. The NIST14 mass spectrum library was used to identify the components. Results. It has been revealed that the tinctures of Anisum vulgare Gaertrn., Foeniculum vulgare Mill., Coriandrum sativum L. Anethum graveolens L., and Carum carvi L. differ in qualitative and quantitative composition of components of chromato-mass spectrometry. Tinctures of Anethum fructus contain 28 components, among which 8.028 RT (-)-Carvone (52.63 %) and 4.861 RT D-Limonene (17.74 %) prevail. Tinctures of Coriandrum fructus contain 37 components with the highest content of 11,016 RT Benzene, 1-(1,5-dimethyl-4-hexenyl)-4-methyl (20.7 %) and 19.372 RT 1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one (8.57 %). In the tincture of Carum carvi L., which contains 33 components, the following may be considered predominant: 7.988 RT Benzaldehyde, 4-(1-methylethyl) (47.37 %) and 19,311 RT undetermined compound (5.88 %). The tincture of Anisum fructus has 22 components, with the highest content of 8.531 RT Estragole (60.32 %) and 4.852 RT D-Limonene (5.15 %); Foeniculum fructus tincture contains 52 components, among which 5.745 RT Fenchone (15.39 %) and 8.5 RT Anethole (11.37 %) prevail. Conclusions. The results of gas chromatography of fruits of the Apiaceae family significantly expand the information about the chemical composition of raw materials and indicate the prospects for use in pharmaceutical and medical practice. Analyzing the results of gas chromatography, it has been found that tinctures of fruits of the Apiaceae family differ in qualitative and quantitative composition of components. Tinctures of Foeniculum fructus contain 52 components, Coriandrum fructus – 37 components, Carum carvi L. contain 33 components, Anethum fructus – 28 components, Anisum fructus – 22 components. The obtained experimental data can be used to create regulatory documentation for a particular type of medicinal plant raw materials.


1999 ◽  
Vol 5 (1-2) ◽  
Author(s):  
É. Stefanovits-Bányai ◽  
L. Boross ◽  
J. Bernáth ◽  
I. Kerepesi ◽  
M. Kiss ◽  
...  

Differences were demonstrated in esterasei coenzyme pattern of some essential oil producing plants belonging to the Apiaceae family — fennel (Foeniculum vulgare Mill.), angelica (Angelica archangelica L.), lovage (Levisticum officinale Koch.), dill (Anethum graveolens L.), coriander (Coriandrum sativum L.), anise (Pimpinella anisum L.), caraway (Carum carvi L.) — as well as differences between two varieties of fennel seed by using isoelectric focusing. That method provides quality control in essential oil plants and is suitable to describe isoenzyme pattern characteristic for taxons. Based on our findings, isoelectric focusing seems to be suitable for identification and differentiation of different plant samples, providing an easy tool for further processing as well as for breeding. Our further aim is to apply that method to differentiate among samples belonging to the same species according to their value of inner content.  


Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3625
Author(s):  
Hafedh Hajlaoui ◽  
Soumaya Arraouadi ◽  
Emira Noumi ◽  
Kaïss Aouadi ◽  
Mohd Adnan ◽  
...  

Herbs and spices have been used since antiquity for their nutritional and health properties, as well as in traditional remedies for the prevention and treatment of many diseases. Therefore, this study aims to perform a chemical analysis of both essential oils (EOs) from the seeds of Carum carvi (C. carvi) and Coriandrum sativum (C. sativum) and evaluate their antioxidant, antimicrobial, anti-acetylcholinesterase, and antidiabetic activities alone and in combination. Results showed that the EOs mainly constitute monoterpenes with γ-terpinene (31.03%), β-pinene (18.77%), p-cymene (17.16%), and carvone (12.20%) being the major components present in C. carvi EO and linalool (76.41%), γ-terpinene (5.35%), and α-pinene (4.44%) in C. sativum EO. In comparison to standards, statistical analysis revealed that C. carvi EO showed high and significantly different (p < 0.05) antioxidant activity than C. sativum EO, but lower than the mixture. Moreover, the mixture exhibited two-times greater ferric ion reducing antioxidant power (FRAP) (IC50 = 11.33 ± 1.53 mg/mL) and equipotent chelating power (IC50 = 31.33 ± 0.47 mg/mL) than the corresponding references, and also potent activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) (IC50 = 19.00 ± 1.00 mg/mL), β-carotene (IC50 = 11.16 ± 0.84 mg/mL), and superoxide anion (IC50 = 10.33 ± 0.58 mg/mL) assays. Antimicrobial data revealed that single and mixture EOs were active against a panel of pathogenic microorganisms, and the mixture had the ability to kill more bacterial strains than each EO alone. Additionally, the anti-acetylcholinesterase and α-glucosidase inhibitory effect have been studied for the first time, highlighting the high inhibition effect of AChE by C. carvi (IC50 = 0.82 ± 0.05 mg/mL), and especially by C. sativum (IC50 = 0.68 ± 0.03 mg/mL), as well as the mixture (IC50 = 0.63 ± 0.02 mg/mL) compared to the reference drug, which are insignificantly different (p > 0.05). A high and equipotent antidiabetic activity was observed for the mixture (IC50 = 0.75 ± 0.15 mg/mL) when compared to the standard drug, acarbose, which is about nine times higher than each EO alone. Furthermore, pharmacokinetic analysis provides some useful insights into designing new drugs with favorable drug likeness and safety profiles based on a C. carvi and C. sativum EO mixture. In summary, the results of this study revealed that the combination of these EOs may be recommended for further food, therapeutic, and pharmaceutical applications, and can be utilized as medicine to inhibit several diseases.


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