Synergism of organic zinc salts and sulfhydril compounds (thiols) in the protection of mice against acute ethanol toxicity, and protective effects of various metal salts

Eliminating all kinds of harmful organisms is an important task in agriculture, food production, and human life. Quinone oximes and their salts are good bioactive compounds to attain this aim. The alkali metal salts of quinone mono- and dioxime have been synthesized by the reaction of the corresponding quinone oxime with alkali metal hydroxide. The divalent metal salts have been obtained in two stages. The first stage is the synthesis of the sodium salt of the quinone oxime. The second step is the reaction of the latter with a divalent metal salt. Copper and zinc salts of [(4-oxocyclohexa-2,5-dien-1-ylidene)amino]oxidanide have the highest insecticidal activity against the housefly and rice weevil. The death index is 90–100%. Copper {[2-methyl-4-oxo-5-(propan-2-yl)cyclohexa-2,5-dien-1-ylidene]amino}oxidanide shows good activity against Phytophthora infestans. Inhibition of the growth and development of the Phytophthora infestans is 80%.

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Organic Zinc Salts as Pro-Ecological Activators for Sulfur Vulcanization of Styrene–Butadiene Rubber

Polymers ◽

10.3390/polym11101723 ◽

2019 ◽

Vol 11 (10) ◽

pp. 1723 ◽

Cited By ~ 4

Author(s):

Magdalena Maciejewska ◽

Anna Sowińska ◽

Judyta Kucharska

Keyword(s):

Zinc Oxide ◽

Styrene Butadiene Rubber ◽

Butadiene Rubber ◽

Zinc Ions ◽

Organic Zinc ◽

Rubber Compounds ◽

Curing Characteristics ◽

Sulfur Vulcanization ◽

Zinc Salts ◽

Styrene Butadiene

Organic zinc salts and complexes were applied as activators for sulfur vulcanization of styrene–butadiene elastomer (SBR) in order to reduce the content of zinc ions in rubber compounds as compared with conventionally used zinc oxide. In this article, the effects of different organic zinc activators on the curing characteristics, crosslink densities, and mechanical properties of SBR as well as the aging resistance and thermal behavior of vulcanizates are discussed. Organic zinc salts seem to be good substitutes for zinc oxide as activators for sulfur vulcanization of SBR rubber, without detrimental effects to the vulcanization time and temperature. Moreover, vulcanizates containing organic zinc salts exhibit higher tensile strength and better damping properties than vulcanizate crosslinked with zinc oxide. The application of organic zinc activators allows the amount of zinc ions in SBR compounds to be reduced by 70–90 wt % compared to vulcanizate with zinc oxide. This is very important for ecological reasons, since zinc oxide is classified as being toxic to aquatic species.

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Lipid peroxidation: A mechanism involved in acute ethanol toxicity as demonstrated by in vivo pentane production in the rat

Lipids ◽

10.1007/bf02533677 ◽

1978 ◽

Vol 13 (4) ◽

pp. 305-307 ◽

Cited By ~ 72

Author(s):

Richard E. Litov ◽

Dennis H. Irving ◽

Jeanne E. Downey ◽

Al L. Tappel

Keyword(s):

Lipid Peroxidation ◽

Ethanol Toxicity ◽

Acute Ethanol ◽

Pentane Production

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Contractile Protein Synthesis in the Jejunum Seromuscular Layer of the Rat and its Response to Acute Ethanol Toxicity

Clinical Science ◽

10.1042/cs079012pa ◽

1990 ◽

Vol 79 (s23) ◽

pp. 12P-12P

Author(s):

J S Marway ◽

V R Preedy ◽

T J Peters

Keyword(s):

Protein Synthesis ◽

Contractile Protein ◽

Ethanol Toxicity ◽

Acute Ethanol ◽

Seromuscular Layer

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Alpha-Ketoglutarate Partially Protects Fruit Fly Drosophila Melanogaster from Ethanol Toxicity

Journal of Vasyl Stefanyk Precarpathian National University ◽

10.15330/jpnu.2.1.115-121 ◽

2015 ◽

Vol 2 (1) ◽

pp. 115-121 ◽

Cited By ~ 2

Author(s):

Halyna Shmihel

Keyword(s):

Amino Acids ◽

Krebs Cycle ◽

Fruit Fly ◽

Protective Effects ◽

Developmental Effects ◽

Toxic Agents ◽

Ethanol Toxicity ◽

Important Intermediate ◽

Living Organisms ◽

Model Subject

Alpha-ketoglutarate (AKG) is an important intermediate in Krebs cycle and inmetabolism of amino acids. Recently, it was proposed to apply as a dietary supplement to improveoverall functional state of living organisms. In particular, AKG was supposed to use underexposure of animals and cell cultures to many toxic agents. In this context, this study aimed toelucidate the ability of dietary AKG to reduce toxic effects of ethanol on development of fruit flyDrosophila melanogaster, which is a popular model subject to research many aspects of biology ofhigher eukaryotes. For this aim, the effect of sodium salt of AKG on pupation speed of D.melanogaster w1118 on the medium supplemented with different concentrations of ethanol wasstudied. Ethanol at a low concentration (2%) did not affect the rate of larval pupation, whereas athigher concentrations it significantly delayed fly pupation and showed developmental toxicityreducing a number of total pupae formed. The most toxic developmental effects of ethanol wereobserved at its highest concentration (15%). The potential mechanisms of protective effects of AKGare discussed

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