Inhibition of transforming growth factor alpha stimulation of human squamous cell carcinoma of the head and neck with anti-TGF-α antibodies and tyrphostin

1997 ◽  
Vol 4 (8) ◽  
pp. 670-684 ◽  
Author(s):  
Carmen C. Solorzano ◽  
Shawn C. Jones ◽  
Mark Pettitjean ◽  
Thomas G. O'Daniel ◽  
Troy Auffenberg ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Alpha ◽  
Human Squamous Cell Carcinoma ◽  
Factor Alpha ◽  
Stimulation Of

Investigation of urinary transforming growth factor alpha levels as tumor markers in patients with advanced squamous cell carcinoma of the head and neck

Head & Neck ◽  
1990 ◽  
Vol 12 (5) ◽  
pp. 411-416 ◽  
Author(s):  
Mary Fazekas-May ◽  
James Y. Suen ◽  
Yun Chi Yeh ◽  
Hsing Wu Yeh ◽  
Lynda Beth Milligan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Tumor Markers ◽  
Squamous Cell ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Alpha ◽  
Advanced Squamous Cell Carcinoma ◽  
Factor Alpha

scholarly journals Transforming Growth Factor Alpha Stimulation of Mucosal Tissue Cultures from Head and Neck Squamous Cell Carcinoma Patients Increases Chemoresistance to Cisplatin

Chemotherapy ◽  
2010 ◽  
Vol 56 (4) ◽  
pp. 268-274 ◽  
Author(s):  
Philipp Baumeister ◽  
Maximilian Reiter ◽  
Sabina Schwenk-Zieger ◽  
Ulrich Harréus
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Alpha ◽  
Mucosal Tissue ◽  
Tissue Cultures ◽  
Factor Alpha ◽  
Stimulation Of

In vitro secretion of transforming growth factor alpha (TGF-α): A comparison of the A431 cell line with three human oesophageal squamous cell carcinoma lines

1992 ◽  
Vol 12 (4) ◽  
pp. 293-302 ◽  
Author(s):  
A. L. Thornley ◽  
G. J. Jones
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Cell Carcinoma ◽  
Cell Line ◽  
Squamous Cell ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Alpha ◽  
Oesophageal Squamous Cell Carcinoma ◽  
Factor Alpha ◽  
A431 Cell Line

Transforming growth factor alpha (TGF-α) is a single chain polypeptide which exists in a variety of forms differing in molecular weight. These forms are variously present in normal and neoplastic cells. Of particular interest are TGF-α's well-known mitogenic properties. The transition from a normal to a neoplastic cellular state results from signalling defects that may depend upon, iter alia, abonormal levels of expression and secretion of TGF-α. It is known that the secretion of TGF-α may be enhanced appreciably by agents such as phorbol 12-myristate 13-acetate (PMA), serum factors and epidermal growth factor (EGF). Here, we compare the efficacy of these three agents in the elevation of TGF-α secretion in the well studied A431 cell line with their previously undocumented efficacy in certain interesting, but little known, human oesophageal squamous cell carcinoma (SCC) lines.

Defects in the opioid growth factor receptor in human squamous cell carcinoma of the head and neck

Cancer ◽  
2003 ◽  
Vol 97 (7) ◽  
pp. 1701-1710 ◽  
Author(s):  
Patricia J. McLaughlin ◽  
Brendan C. Stack ◽  
Roger J. Levin ◽  
Fred Fedok ◽  
Ian S. Zagon
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Growth Factor Receptor ◽  
Opioid Growth Factor ◽  
Human Squamous Cell Carcinoma

scholarly journals Transforming growth factor β1 enhances stemness of head and neck squamous cell carcinoma cells through activation of Wnt signaling

2016 ◽  
Vol 12 (6) ◽  
pp. 5315-5320 ◽  
Author(s):  
Woo-Jin Bae ◽  
Sang-Hyuk Lee ◽  
Young-Soo Rho ◽  
Bon-Seok Koo ◽  
Young-Chang Lim
Keyword(s):  
Squamous Cell Carcinoma ◽  
Growth Factor ◽  
Wnt Signaling ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β1 ◽  
Carcinoma Cells ◽  
Neck Squamous Cell Carcinoma
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