Determination of an optimum radiation dose in a tumor tissue-normal tissue system

1997 ◽  
Vol 31 (4) ◽  
pp. 204-208
Author(s):  
L. Ya. Klepper
Keyword(s):  
Radiation Dose ◽  
Normal Tissue ◽  
Tumor Tissue ◽  
Tissue System

APPLICATION OF PIXE TO CANCER RESEARCH

1992 ◽  
Vol 02 (04) ◽  
pp. 529-534 ◽  
Author(s):  
HUIYING YAO ◽  
XIANZHOU ZENG ◽  
JIYAO CHEN ◽  
WEN CHEN ◽  
HUAIXIN CAI ◽  
...  
Keyword(s):  
Cancer Research ◽  
Trace Elements ◽  
Photodynamic Therapy ◽  
Normal Tissue ◽  
Second Generation ◽  
Tumor Tissue ◽  
Photodynamic Effect ◽  
Malignant Tumours ◽  
Local Destruction

Photodynamic therapy (PDT) is a promising approach to the local destruction of malignant tumours. This method is based on the partially selective retension in tumor tissue of the photosensitizers which have photodynamic effect. It is important for PDT to determine the photosentizer concentration in tumor and in normal tissue. We quantitatively analysed the concentration of the metallic phthalocyanines, a class of photosensitizers now recognized as “second generation” PDT drugs and studied its action in different time by PIXE technique. The paper shows also the correlation between trace elements and cancer.

scholarly journals Effect of immunoadjuvants on the disease course in patients with operable breast cancer

2019 ◽  
Vol 14 (4) ◽  
pp. 20-23
Author(s):  
M. M. Vasilyeva ◽  
I. P. Moshurov ◽  
L. Yu. Grivtsova ◽  
N. N. Tupitsyn ◽  
N. A. Kozlov ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumor Tissue ◽  
Radical Mastectomy ◽  
Control Group ◽  
Cancer Management ◽  
New Strategy ◽  
Breast Cancer Management ◽  
Grade Ii ◽  
And Control

Background. A new strategy of breast cancer management is required for effective disease prevention and control. Immunotherapy is one of promising options.Objective: to evaluate the effect of immunoadjuvant polyoxidonium on pathmorphological changes in breast tumors.Materials and methods. The study was performed in 75 patients with breast cancer: 50 patients received polyoxidonium in a neoadjuvant regimen (main group), 25 patients did not receive polyoxidonium (control group). Polyoxidonium at a dose of 12 mg was administered intramuscularly 1 time per day on the days 1, 2, 3, 5 and 7 before surgery; on the day 8, radical mastectomy was performed in patients of both groups, followed by histological examination and determination of the grade of therapeutic pathomorphosis of the tumor.Results. The proportion of cases with grade I therapeutic pathomorphosis was 58 %, grade II therapeutic pathomorphosis – 6 %. Pathomorphosis in metastatic lymph nodes was observed in 22.7 % of cases.Conclusion. The anti-tumor effect of polyoxidonium was confirmed on the basis of the induction of pathomorphosis of the tumor tissue of breast cancer.

scholarly journals Determination of natural thorium isotopes (230Th and 232Th) in calcium and magnesium supplements and the potential effective exposure radiation dose for human

2021 ◽  
pp. 104263
Author(s):  
Aleksandra Moniakowska ◽  
Klaudia Block-Łaszewska ◽  
Dagmara Strumińska-Parulska
Keyword(s):  
Radiation Dose ◽  
Calcium And Magnesium ◽  
Thorium Isotopes

scholarly journals EP-1122: Use of a dynamic thorax phantom for radiation dose determination of a floating target in Extracranial Stereotactic RT

2013 ◽  
Vol 106 ◽  
pp. S423
Author(s):  
C. Moustakis ◽  
Y. Eschrich ◽  
I. Ernst ◽  
B. Czekalla ◽  
F. Büther ◽  
...  
Keyword(s):  
Radiation Dose ◽  
Dose Determination

In Vivo Imaging of Dynamic Shear Modulus of Rodent Mammary Tumors Using Ultrasound

2012 ◽  
Author(s):  
Yue Wang ◽  
Michael Insana
Keyword(s):  
In Vivo Imaging ◽  
Normal Tissue ◽  
Breast Tissue ◽  
Structural Integrity ◽  
Biomechanical Properties ◽  
Dynamic Shear Modulus ◽  
Living Tissue ◽  
Dynamic Shear

Biomechanical properties of living tissue are very important in maintaining normal tissue function, cellular and extracellular structural integrity. Therefore, the quantitative determination of biomechanical properties of breast tissue, especially in vivo, serves an important role in clinical diagnosis.

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