Long-term effects of high-fat diets on peroxisomal β-oxidation in male and female rats

Lipids ◽  
1985 ◽  
Vol 20 (10) ◽  
pp. 668-674 ◽  
Author(s):  
M. S. Thomassen ◽  
J. Norseth ◽  
E. N. Christiansen
1976 ◽  
Vol 71 (1) ◽  
pp. 109-114 ◽  
Author(s):  
I. DONIACH ◽  
D. J. SHALE

SUMMARY From the differences in radiation profiles between 131I and 125I isotopes of iodine it would be expected that they would show different effects on thyroid function. The differences should lead to lower rates of thyroid gland destruction with 125I and hence less post-irradiation hypothyroidism. This difference in biological effect has been demonstrated in rats by indirect assessment of thyroid function. In this report the long-term effects of a range of similar doses of 131I and 125I were compared, in male and female rats, by direct assessment of thyroid function. Seventeen months after receiving 25 and 125 μCi of 131I, male and female rats showed significant elevation of serum TSH concentration and a reduction in 3 h radioiodine uptake. Rats receiving 1 and 5 μCi of 131I and all doses of 125I showed no significant changes in thyroid function. These findings confirm the previously reported differences in effect between the 131I and 125I isotopes of iodine in the rat.


2010 ◽  
Vol 26 (3) ◽  
pp. 291-302 ◽  
Author(s):  
Antònia Nadal-Casellas ◽  
Emilia Amengual-Cladera ◽  
Ana María Proenza ◽  
Isabel Lladó ◽  
Magdalena Gianotti

1965 ◽  
Vol 48 (4) ◽  
pp. 556-560 ◽  
Author(s):  
Jerome A. Grunt ◽  
Russell D. Cunningham

ABSTRACT Thyroid function has been evaluated in male and female rats which had been either sham operated, gonadectomized, adrenalectomized, or adrenalectomized and gonadectomized on day 25, and killed at 180 days of age. No hormonal replacement therapy was utilized. Animals without adrenals showed increased thyroid weights, increased cell heights of follicular epithelium and decreased resin binding of 131I labeled triiodothyronine without significant changes in BEI. Possible mechanisms for these changes in thyroid function are discussed.


2007 ◽  
Vol 7 (4) ◽  
pp. 247-254 ◽  
Author(s):  
Mariann R. Piano ◽  
David L. Geenen ◽  
Dorie W. Schwertz ◽  
Shamim A. K. Chowdhury ◽  
Milina Yuzhakova

2006 ◽  
Vol 190 (1) ◽  
pp. 43-49 ◽  
Author(s):  
Bruce A. Rasmussen ◽  
Jahn O’Neil ◽  
Kebreten F. Manaye ◽  
David C. Perry ◽  
Yousef Tizabi

Bone ◽  
2009 ◽  
Vol 45 (6) ◽  
pp. S157
Author(s):  
E. Hernández ◽  
C. Suarez ◽  
A. Ferreira Monteiro ◽  
P. Rodriguez ◽  
M. Gonzáles-Chaves ◽  
...  

2021 ◽  
Author(s):  
Robert Phillips ◽  
Deborah Jaffey ◽  
Terry Powley

Electrical stimulation is a potential therapy for gastric disorders. Here we describe our surgical procedure for the implantation of patch electrodes on the muscle wall of the stomach of both male and female rats for use in chronic studies looking at the long-term effects of stimulation on physiology and behavior. The surgery is well tolerated by the subjects as rats return to pre-surgical body weight and normal solid chow intake within 7 to 10 days post-surgery. In our hands, rats implanted using the methods described below have been continuously run in feeding and motility experiments for 8 to 12 weeks with minimal to no loss of subjects. When failure does occur, it is typically a result of back mount failure at the site of attachment of the overhead tether to the back mount.


Author(s):  
Eva M. Marco ◽  
Sara Peñasco ◽  
María-Donina Hernández ◽  
Anabel Gil ◽  
Erika Borcel ◽  
...  

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