Malignant tumor cell lines produce interleukin-1-like factor

1988 ◽  
Vol 24 (8) ◽  
pp. 753-758 ◽  
Author(s):  
Shinobu Miyauchi ◽  
Takamasa Moroyama ◽  
Seishi Kyoizumi ◽  
Jun-Ichi Asakawa ◽  
Tetsuji Okamoto ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Malignant Tumor ◽  
Interleukin 1 ◽  
Tumor Cell Lines ◽  
Malignant Tumor Cell

Detection of SNPs of Dck and Cda Genes in Five Hematological Malignant Tumor Cell Lines

Blood ◽  
2012 ◽  
Vol 120 (21) ◽  
pp. 5129-5129
Author(s):  
Zhang Xiaoping ◽  
Ziying Jian ◽  
Bao-An Chen ◽  
Peipei Xu ◽  
Miaoxin Peng ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Malignant Tumor ◽  
Conflicts Of Interest ◽  
Cytidine Deaminase ◽  
Raji Cell ◽  
Tumor Cell Lines ◽  
Nucleotide Polymorphisms ◽  
Malignant Tumor Cell ◽  
System Cell

Abstract Abstract 5129 Background & Aim: This study detected single nucleotide polymorphisms (SNPs) of deoxycytidine kinase(DCK) gene, cytidine deaminase(CDA) gene in five hematological malignant tumor cell lines, to find connections between sNPs and Cytarabine dose selection in the treatment of some hematopathy. Materials & Methods: Cell line K562, Ka, HL-60, U937, and Raji were cultured. The genomic DNA was isolated by QIAamp DNA Blood Mini kit. Designing primes were amplified by PCR to get the related DNA fragments. DCK gene A674G(rs111454937) C1644T(rs72552079), CDA gene A79C(rs2072671) G208A(rs60369023) was genotyped by means of matrix assisted laser desorption ionisation-time of flight mass spectrometry method (MALDI-TOF MS). Results: The genotype of locus A674G(rs111454937) on DCK gene in all five hematology system cell lines was AA; The genotype of locus C1644T(rs72552079) on DCK gene in all five hematology system cell lines was CC. The genotype of locus G208A(rs60369023) on CDA gene in all five hematology system cell lines was GG; For HL-60, U937, and Raji cell lines, the genotype of locus A79C(rs2072671) on CDA gene was AA, while for K562 and Ka cell lines, that was C/A. Conclusions: The genotype of locus A79C(rs2072671) on CDA gene was not all the same in the detected hematological malignant tumor cell lines, while the genotypes of the other 3 loci were same in the 5 cell lines. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Co-production of Interleukin-1 and Interleukin-6 in Tumor Cell Lines Elaborating Colony-stimulating Factors

1991 ◽  
Vol 82 (8) ◽  
pp. 890-892 ◽  
Author(s):  
Yoshiaki Okuno ◽  
Takayuki Takahashi ◽  
Akira Suzuki ◽  
Manabu Fukumoto ◽  
Kishiko Nakamura ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Interleukin 6 ◽  
Interleukin 1 ◽  
Tumor Cell Lines ◽  
Colony Stimulating Factors

INTERLEUKIN-1 RECEPTOR ANTAGONIST INHIBITS GROWTH MODULATION OF HUMAN TUMOR-CELL LINES BY INTERLEUKIN-1 IN-VITRO

1994 ◽  
Author(s):  
E OELMANN ◽  
MS TOPP ◽  
B REUFI ◽  
C PAPADIMITRIOU ◽  
M KOENIGSMANN ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Receptor Antagonist ◽  
Cell Lines ◽  
Interleukin 1 ◽  
Human Tumor ◽  
Tumor Cell Lines ◽  
Human Tumor Cell ◽  
Growth Modulation ◽  
Human Tumor Cell Lines

Expression of HIF-1a and VEGF in human pituitary tumors and rodent pituitary tumor cell lines under hypoxia-mimicking condition

2008 ◽  
Vol 116 (09) ◽  
Author(s):  
B Shan ◽  
C Onofri ◽  
M Theodoropoulou ◽  
E Arzt ◽  
GK Stalla ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Pituitary Tumor ◽  
Pituitary Tumors ◽  
Tumor Cell Lines ◽  
Human Pituitary ◽  
Pituitary Tumor Cell

Interaction of Human Tumor Cells with Human Platelets and the Coagulation System

1983 ◽  
Vol 50 (03) ◽  
pp. 726-730 ◽  
Author(s):  
Hamid Al-Mondhiry ◽  
Virginia McGarvey ◽  
Kim Leitzel
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Cell Lines ◽  
Human Tumor ◽  
Human Platelets ◽  
Factor Vii ◽  
Coagulation System ◽  
Breast Adenocarcinoma ◽  
Activate Factor ◽  
Tumor Cell Lines

SummaryThis paper reports studies on the interaction between human platelets, the plasma coagulation system, and two human tumor cell lines grown in tissue culture: Melanoma and breast adenocarcinoma. The interaction was monitored through the use of 125I- labelled fibrinogen, which measures both thrombin activity generated by cell-plasma interaction and fibrin/fibrinogen binding to platelets and tumor cells. Each tumor cell line activates both the platelets and the coagulation system simultaneously resulting in the generation of thrombin or thrombin-like activity. The melanoma cells activate the coagulation system through “the extrinsic pathway” with a tissue factor-like effect on factor VII, but the breast tumor seems to activate factor X directly. Both tumor cell lines activate platelets to “make available” a platelet- derived procoagulant material necessary for the conversion of prothrombin to thrombin. The tumor-derived procoagulant activity and the platelet aggregating potential of cells do not seem to be inter-related, and they are not specific to malignant cells.

Differential Increases in Glutathione S-Transferase Activities in a Range of Multidrug-Resistant Human Tumor Cell Lines

1989 ◽  
Vol 1 (6) ◽  
pp. 359-365 ◽  
Author(s):  
Richard D. H. Whelan ◽  
Louise K. Hosking ◽  
Alan J. Townsend ◽  
Kenneth H. Cowan ◽  
Bridget T. Hill
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Human Tumor ◽  
Multidrug Resistant ◽  
Tumor Cell Lines ◽  
Glutathione S Transferase ◽  
Human Tumor Cell ◽  
Human Tumor Cell Lines

Cytotoxic Activities of Red Algae Collected from Jeju Island Against Four Tumor Cell Lines

2006 ◽  
Vol 11 (3) ◽  
pp. 177-183 ◽  
Author(s):  
Kil-Nam Kim ◽  
Ki-Wan Lee ◽  
Choon-Bok Song ◽  
Chang-Bum Ahn ◽  
You-Jin Jeon
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Red Algae ◽  
Jeju Island ◽  
Cytotoxic Activities ◽  
Tumor Cell Lines
Sign in / Sign up

Export Citation Format

Share Document