Study on effect of kangyanling ("Equation missing" No EquationSource Format="TEX", only image )on cytokine and C-reactive protein inpatients of systemic inflammatory reaction syndrome and multi-organ dysfunction syndrome after abdominal surgery)on cytokine and C-reactive protein inpatients of systemic inflammatory reaction syndrome and multi-organ dysfunction syndrome after abdominal surgery

2001 ◽  
Vol 7 (2) ◽  
pp. 98-98
Author(s):  
Zhe-yu Chen ◽  
Qing-hui Qi
2021 ◽  
Vol 100 (6) ◽  
pp. 162-167
Author(s):  
L.N. Mazankova ◽  
◽  
O.V. Molochkova ◽  
O.В. Kovalev ◽  
O.V. Shamsheva ◽  
...  

During the COVID-19 pandemic, it is necessary to be wary of the development of pediatric multisystem inflammatory syndrome in children (PMIS) who have had a COVID-19 and had antibodies to the SARS-CoV-2 virus. The aim of this work is to describe two clinical cases in children with antibodies to SARS-CoV-2 against the background of yersiniosis in a 12-year-old child and salmonellosis in a 3-year-old child, which proceeded with a pronounced inflammatory reaction and required a differential diagnosis with multisystem inflammatory syndrome. These bacterial infections proceeded with severe intoxication and fever, had a polymorphic clinical picture with exanthema syndrome, conjunctivitis/scleritis, swelling of the palms/feet, diarrhea and toxic kidney damage, with a pronounced systemic inflammatory reaction – high leukocytosis with neutrophilia and lymphopenia, a significant increase in C-reactive protein, procalcitonin, hypercoagulability (increased fibrinogen, D-dimer). Etiotropic antibiotic therapy led to recovery in both cases. Conclusions: During the COVID-19 pandemic, if antibodies to the SARS-CoV-2 virus are detected in children in the presence of signs of systemic inflammation and corresponding symptoms, the alertness of doctors and a timely comprehensive examination are necessary to exclude bacterial infections, also characterized by signs of systemic inflammation, for the purpose of differential diagnosis of PMIS.


Surgery ◽  
2021 ◽  
Author(s):  
Victor D. Plat ◽  
Daan M. Voeten ◽  
Freek Daams ◽  
Donald L. van der Peet ◽  
Jennifer Straatman

2002 ◽  
Vol 62 (3) ◽  
pp. 189-194 ◽  
Author(s):  
M. Lindberg ◽  
A. Åsberg ◽  
H. E. Myrvold ◽  
A. Hole ◽  
A. Rydning ◽  
...  

2020 ◽  
Vol 158 (6) ◽  
pp. S-1576-S-1577
Author(s):  
Bernardo Borraez-Segura ◽  
Juan Pablo Orozco ◽  
Felipe Anduquia ◽  
Natalia Hurtado ◽  
Alvaro Rodriguez

2019 ◽  
Vol 58 (7) ◽  
pp. 752-760 ◽  
Author(s):  
Christopher M. Horvat ◽  
Jamie Bell ◽  
Sajel Kantawala ◽  
Alicia K. Au ◽  
Robert S. B. Clark ◽  
...  

Our objective was to determine if C-reactive protein (CRP) and ferritin values alone and in combination are associated with mortality among hospitalized children. All hospitalized patients at our institution with a CRP or ferritin assay in 2015 and 2016 were included. Area under the receiver operating curves (AUROC) were examined, optimal cut-points determined, and patients were stratified into low-, intermediate-, or high-risk groups based on elevation of zero, one, or both biomarkers. A total of 14 928 CRP and 653 ferritin values were obtained, with both obtained for 172 patients. AUROC for maximum CRP value was 0.76 (0.68-0.85) with a cut-point of 7.1 mg/dL for in-hospital mortality and 0.90 (0.83-0.98) for maximum ferritin with a cut-point of 373 ng/mL. Elevation of both ferritin and CRP was associated with the highest inpatient mortality (21.7%) and greatest organ dysfunction, followed by either biomarker alone. Additional prospective study of these biomarkers in combination is warranted.


2010 ◽  
Vol 63 (3-4) ◽  
pp. 267-273
Author(s):  
Dragan Mikic ◽  
Gordana Arsic-Komljenovic ◽  
Darko Nozic ◽  
Milica Cucuz ◽  
Radmila Dimitrijevic ◽  
...  

Introduction Since the outcome in septic patients can significantly be improved if the appropriate therapy is introduced timely early, the early diagnosis of sepsis and its complications is essential. The aim of this study was to compare mean values of the initial blood concentrations of lactate, C-reactive protein and creatinine and the severity of illness and the outcome of sepsis. Materials and methods A total of 30 septic patients were included in the study. The diagnosis of sepsis and its complications was made according to consensus criteria. The severity of illness was scored by an Acute Physiology, Age and Chronic Health Evaluation septic score. The patients were subdivided into different groups, those with sepsis, severe sepsis or septic shock, those with or without multiple organ dysfunction syndrome, and survivors and non-survivors. Results The differences in mean values of lactate levels among all studied groups were significantly high, whereas the level of C-reactive protein were significantly higher only in the non-survivors compared to the survivors (p<0.05). The concentrations of creatinine were significantly higher in the patients with septic shock compared to the patients with sepsis, and in the patients with multiple organ dysfunction syndrome and the non-survivors compared to the corresponding groups (p<0.05). The septic score clearly discriminated patients with different severity of sepsis, development of multiple organ dysfunction syndrome and survival and positively correlated with the concentrations of lactate, C-reactive protein and creatinine (the best correlation ranks were with lactate levels, p<0.001). Discussion and conclusion Our results suggest that lactate level is a better parameter of illness severity and outcome of sepsis than levels of C-reactive protein and creatinine. When compared to the above parameters, the septic score determined on the day of admission to hospital is a much better criterion to classify patients into groups with different severity of sepsis, with and without multiple organ dysfunction syndrome and into survivors and non-survivors.


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