NICOTINIC ACID DERIVATIVES LOWER FREE FATTY ACID LEVELS

InPharma ◽  
1979 ◽  
Vol 209 (1) ◽  
pp. 14-14 ◽  
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Nicotinic Acid ◽  
Nicotinic Acid Derivatives ◽  
Lower Free Fatty Acid

scholarly journals Plasma ?-hydroxybutyric acid response to nicotinic acid-induced plasma free fatty acid decrease in man

Diabetologia ◽  
1966 ◽  
Vol 2 (2) ◽  
pp. 127-129 ◽  
Author(s):  
L. A. Carlson ◽  
J. �stman
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Nicotinic Acid ◽  
Plasma Free Fatty Acid ◽  
Hydroxybutyric Acid

Biphasic Nature of Blood Glucose and Free Fatty Acid Changes Following Intravenous Nicotinic Acid in Man

1967 ◽  
Vol 27 (3) ◽  
pp. 440-443 ◽  
Author(s):  
E. J. PINTER ◽  
C. J. PATTEE
Keyword(s):  
Fatty Acid ◽  
Blood Glucose ◽  
Free Fatty Acid ◽  
Nicotinic Acid

Mechanism of regulation of glucose production by lipolysis in humans

1992 ◽  
Vol 262 (3) ◽  
pp. E353-E358 ◽  
Author(s):  
F. Jahoor ◽  
S. Klein ◽  
R. Wolfe
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Nicotinic Acid ◽  
Plasma Insulin ◽  
Glucose Production ◽  
Plasma Free Fatty Acid ◽  
Insulin Levels ◽  
Plasma Insulin Levels ◽  
Normal Humans ◽  
The Relationship

The relationship between the rate of lipolysis and rate of glucose production (Ra) was investigated in 14- and 86-h fasted humans. [6,6-2H]glucose and [2H]5glycerol were infused to measure glucose and glycerol Ra in response to infusions of nicotinic acid in 14- and 86-h fasted subjects (protocol 1). The response of glucose Ra to nicotinic acid alone and nicotinic acid plus unlabeled glycerol was also measured in 86-h fasted subjects (protocol 2). After a 14-h fast, nicotinic acid caused a 30% decrease in plasma insulin levels and a marked (66%) decrease in plasma free fatty acid levels but did not have any significant effect on glucose Ra and concentration. After 86 h of fasting, nicotinic acid decreased glycerol Ra and hence lipolytic rate by approximately 60%. This caused a significant decrease (P less than 0.05) of 16-20% in glucose Ra and uptake. This decrease in glucose Ra was abolished when unlabeled glycerol was also infused with nicotinic acid to maintain glycerol Ra. These findings suggest that, in normal humans, a decrease in the rate of lipolysis regulates glucose Ra via its effect on the availability of glycerol for gluconeogenesis.

UTILIZATION OF SEED EXTRACTS FROM AVOCADO (Persea americana MILL) TO REDUCE OF FREE FATTY ACID CONTENS IN CRUDE PALM OIL

2018 ◽  
Vol 24 (2) ◽  
pp. 97-102
Author(s):  
Eka Nuryanto ◽  
Iput Pradiko ◽  
Zulfi Prima Sani Nasution
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Palm Oil ◽  
Persea Americana ◽  
Crude Palm Oil ◽  
F Test ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Lower Free Fatty Acid ◽  
Seed Extracts

Mixing Crude Palm Oil (CPO) with high and lower Free Fatty Acid (FFA) is a technique to reduce FFA in CPO. Avocado Seeds Extract (ASE) was expected to reduce the FFA. This study was conducted to test the ability of ASE on reducing ALB in CPO. The variable in this study is ASE solution (0-50 ml). The whole treatment were conducted at same level of o temperatur 60 C, stirring speed (400 rpm) and reaction time (60 minutes). The research was employed non factorial Completely Randomized Design. Statistical analysis was performed using F Test along with Duncan Test. The results showed that addition of ASE can reduce FFA. The results of F Test showed that the addition of 25 ml ASE is the most effective for reduction ALB content (4.65 % to 0.22 %) in CPO.

Effects of noradrenaline and nicotinic acid on plasma free fatty acids and oxygen consumption in cold-adapted rats

1979 ◽  
Vol 57 (7) ◽  
pp. 725-730 ◽  
Author(s):  
Louise Lafrance ◽  
Danièle Routhier ◽  
Bernard Têtu ◽  
Christian Têtu
Keyword(s):  
Fatty Acids ◽  
Oxygen Consumption ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Nicotinic Acid ◽  
Free Fatty Acids ◽  
Simultaneous Increase ◽  
Elevated Plasma ◽  
Cold Adapted ◽  
Plasma Ffa

A 3-h noradrenaline (NA) infusion (1.5 μg kg−1 min−1) produced a sustained enhanced oxygen consumption (O2 cons.) in cold-adapted rats. Plama free fatty acid (FFA) levels were elevated by NA in control and in cold-adapted rats, but to a lesser extent in cold-adapted rats; the increase was maintained at a plateau in both groups during the entire period of NA infusion. A 1-h nicotinic acid (Nic A) infusion (1.5 mg kg−1 min−1) added to the NA infusion inhibited the calorigenic response to NA in cold-adapted rats and reduced the elevated plasma FFA concentration in control and in cold-adapted rats to values below basal levels. However, when the Nic A infusion was stopped, the O2 cons, was increased again in cold-adapted rats by the uninterrupted NA infusion, without the simultaneous increase of the plasma FFA concentration; the plasma FFA concentration was maintained in cold-adapted rats below basal values and merely brought back to basal levels in control rats. From these results, it is suggested that plasma FFA are not an essential substrate to the calorigenic response to NA observed in cold-adapted rats, as 85% of the response can occur when the plasma FFA concentration is very low.

Growth Hormone, Cortisol, and Glucagon Concentrations during Plasma Free Fatty Acid Depression: Different Effects of Nicotinic Acid and an Adenosine Derivative (BM 11.189)*

1983 ◽  
Vol 57 (2) ◽  
pp. 410-414 ◽  
Author(s):  
HANS-JÜRGEN QUABBE ◽  
ALFRED S. LUYCKX ◽  
MANFRED L’AGE ◽  
CORNELIUS SCHWARZ
Keyword(s):  
Growth Hormone ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Nicotinic Acid ◽  
Plasma Free Fatty Acid

INFLUENCE OF SERUM FREE FATTY ACID LEVELS ON GROWTH HORMONE SECRETION IN LACTATING COWS

1975 ◽  
Vol 66 (2) ◽  
pp. 213-224 ◽  
Author(s):  
R. REYNAERT ◽  
M. DE PAEPE ◽  
S. MARCUS ◽  
G. PEETERS
Keyword(s):  
Growth Hormone ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Nicotinic Acid ◽  
Glucose Concentration ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Direct Consequence ◽  
Serum Free Fatty Acid ◽  
Lactating Cows

SUMMARY The influence of intravenous injections or infusions of insulin (0·2 i.u./kg), propranolol (150 mg), 3,5-dimethylpyrazole (3 mg/kg), 3,5-dimethylisoxazole (0·08 mg/kg), glucose (0·5 g/kg), nicotinic acid (120 mg/kg), arginine (0·5 g/kg) or butyrate (0·5 mmol/kg) on plasma glucose levels, and on serum concentrations of growth hormone and free fatty acids of lactating cows was investigated. In all of these experiments we noted an increase in the level of growth hormone. This increase was not a direct consequence of alterations in the glucose concentration, since the growth hormone peak occurred both during a decrease (insulin, 3,5-dimethylisoxazole, nicotinic acid and butyrate tests), and during an increase of the glucose level (glucose, arginine and propranolol tests), whereas the glucose concentration remained unchanged during the 3,5-dimethylpyrazole experiments. However, in each instance a precipitous fall of the free fatty acid level was noted. The glucose, growth hormone, and free fatty acid levels of lactating cows were not affected by either i.v. injection or infusion of saline.

Effects of Nicotinic Acid on the Plasma Pancreatic Glucagon, Insulin and Free Fatty Acid in Diabetic Subjects

1976 ◽  
Vol 8 (06) ◽  
pp. 489-489 ◽  
Author(s):  
Y. Tasaka ◽  
M. Sekine ◽  
Y. Yoshida ◽  
Y. Hirata
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Nicotinic Acid ◽  
Pancreatic Glucagon

scholarly journals ARANG AMPAS TEBU UNTUK MENURUNKAN KADAR ASAM LEMAK BEBAS MINYAK GORENG BEKAS

2018 ◽  
pp. 189-193
Author(s):  
P Purwati ◽  
Tri Harningsih
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Free Fatty Acids ◽  
Fatty Acid Content ◽  
Cooking Oil ◽  
Used Oil ◽  
Used Cooking Oil ◽  
Lower Free Fatty Acid

ABSTRAK Minyak digunakan secara berulangkali mengakibatkan penurunan kualitas minyak. Salah satunya adalah peningkatan asam lemak bebasnya. Limbah ampas tebu yang diubah ke dalam bentuk arang digunakan menurunkan asam lemak bebas pada minyak goreng bekas. Penambahan arang ampas tebu dengan variasi massa dapat menurunkan asam lemak bebas. Asam lemak bebas minyak bekas sebelum ditambah dengan arang ampas tebu adalah 0,62 %. Angka tersebut mengalami penurunan setelah penambahan variasi massa ampas tebu dimulai dengan 2,5 gram; 5,0 gram; 7,5 gram; 10,0 gram dan 12,5 gram. Hasil asam lemak bebas berturut-turut 0,61%; 0,55%; 0,48%; 0,45%; 0,43%. Kondisi optimum dari massa arang ampas tebu sebesar 12,5 gram. Prosentase penurunan asam lemak bebas sebesar 30,41 % dengan kadar asam lemak bebas dari sebelum dilakukan adsorbsi sebanyak 0,61% menjadi 0,43%.   Kata kunci: arang ampas tebu, asam lemak bebas, minyak goreng bekas       ABSTRACT Oils used repeatedly will result in a decrease in the quality of oil. One of which is the increase in free fatty acids. The waste bagasse which is converted into charcoal form used to lower free fatty acid in used oil casting. The addition of charcoal of bagasse with variation of mass can decrease free fatty acid. The fatty acid free of used oil before it is added with sugarcane bagasse is 0,62%. The number decreases after the addition of variation of bagasse mass begins with 2,5 grams; 5,0 grams; 7,5 grams; 10,0 grams and 12; 5 grams. Free fatty acids result are 0,61%; 0,55%; 0,48%; 0,45%; 0; 43% respectively. The optimum condition from the mass of charcoal of bagasse is 12,5 grams. Percentage of free fatty acid decrease of 30,41% with free fatty acid content from before adsorbs 0,61% to 0,43%.   Keywords: charcoal of bagasse, free fatty acids, used cooking oil

scholarly journals UTILIZATION OF SEED EXTRACTS FROM AVOCADO (Persea americana MILL) TO REDUCE OF FREE FATTY ACID CONTENS IN CRUDE PALM OIL

2016 ◽  
Vol 24 (2) ◽  
pp. 97-102
Author(s):  
Eka Nuryanto ◽  
Iput Pradiko ◽  
Zulfi Prima Sani Nasution
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Palm Oil ◽  
Persea Americana ◽  
Crude Palm Oil ◽  
F Test ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Lower Free Fatty Acid ◽  
Seed Extracts

Mixing Crude Palm Oil (CPO) with high and lower Free Fatty Acid (FFA) is a technique to reduce FFA in CPO. Avocado Seeds Extract (ASE) was expected to reduce the FFA. This study was conducted to test the ability of ASE on reducing ALB in CPO. The variable in this study is ASE solution (0-50 ml). The whole treatment were conducted at same level of o temperatur 60 C, stirring speed (400 rpm) and reaction time (60 minutes). The research was employed non factorial Completely Randomized Design. Statistical analysis was performed using F Test along with Duncan Test. The results showed that addition of ASE can reduce FFA. The results of F Test showed that the addition of 25 ml ASE is the most effective for reduction ALB content (4.65 % to 0.22 %) in CPO.

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