Optimization of a complex chemical process using an equation oriented model

Author(s):  
P. V. L. N. Sarma ◽  
G. V. Reklaitis
1991 ◽  
Vol 56 (10) ◽  
pp. 2107-2141 ◽  
Author(s):  
Mirko Dohnal

Qualitative model is a theoretical background of commonsense. Complex qualitative models can have prohibitively many solutions (qualitative states). Therefore a qualitative analogy of such classical quantitative tools as e.g. the decomposition is developed. Practical applications of decomposition principle is nearly always ad hoc. Therefore two case studies are presented in details, a chemical process (mixer, chemical reactor, separator) and an anaerobic fermentor.


2020 ◽  
Vol 74 (5) ◽  
pp. 407-417
Author(s):  
Greg Mann ◽  
Frédéric V. Stanger

Enzymes have the potential to catalyse complex chemical reactions with unprecedented selectivity, under mild conditions in aqueous media. Accordingly, there is serious interest from the pharmaceutical industry to utilize enzymes as biocatalysts to produce medicines in an environmentally sustainable and economic manner. Prominent advances in the field of biotechnology have transformed this potential into a reality. Using modern protein engineering techniques, in a matter of months it is possible to evolve an enzyme, which fits the demands of a chemical process, or even to catalyse entirely novel chemistry. Consequently, biocatalysis is routinely applied throughout the pharmaceutical industry for a variety of applications, ranging from the manufacture of large volumes of high value blockbuster drugs to expanding the chemical space available for drug discovery.


2016 ◽  
Vol 33 (1) ◽  
pp. 155-168 ◽  
Author(s):  
Roxana Both ◽  
Eva-Henrietta Dulf ◽  
Ana-Maria Cormos

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