scholarly journals Effect of hypofractionation on the incidental axilla dose during tangential field radiotherapy in breast cancer

2020 ◽  
Vol 196 (9) ◽  
pp. 771-778 ◽  
Author(s):  
Kai J. Borm ◽  
Markus Oechsner ◽  
Mathias Düsberg ◽  
Gabriel Buschner ◽  
Weber Wolfgang ◽  
...  

2014 ◽  
Vol 90 (1) ◽  
pp. S221-S222 ◽  
Author(s):  
M. Duma ◽  
A. Herr ◽  
M. Oechsner ◽  
S. Kampfer ◽  
K. Trott ◽  
...  


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Marcus Stockinger ◽  
Heiko Karle ◽  
Hannes Rennau ◽  
Sabine Sebb ◽  
Ulrich Wolf ◽  
...  

Abstract Purpose Cardiac effects after breast cancer radiation therapy potentially affect more patients as survival improves. The heart’s heterogeneous radiation exposure and composition of functional structures call for establishing individual relationships between structure dose and specific late effects. However, valid dosimetry requires reliable contouring which is challenging for small volumes based on older, lower-quality computed tomography imaging. We developed a heart atlas for robust heart contouring in retrospective epidemiologic studies. Methods and materials The atlas defined the complete heart and geometric surrogate volumes for six cardiac structures: aortic valve, pulmonary valve, all deeper structures combined, myocardium, left anterior myocardium, and right anterior myocardium. We collected treatment planning records from 16 patients from 4 hospitals including dose calculations for 3D conformal tangential field radiation therapy for left-sided breast cancer. Six observers each contoured all patients. We assessed spatial contouring agreement and corresponding dosimetric variability. Results Contouring agreement for the complete heart was high with a mean Jaccard similarity coefficient (JSC) of 89%, a volume coefficient of variation (CV) of 5.2%, and a mean dose CV of 4.2%. The left (right) anterior myocardium had acceptable agreement with 63% (58%) JSC, 9.8% (11.5%) volume CV, and 11.9% (8.0%) mean dose CV. Dosimetric agreement for the deep structures and aortic valve was good despite higher spatial variation. Low spatial agreement for the pulmonary valve translated to poor dosimetric agreement. Conclusions For the purpose of retrospective dosimetry based on older imaging, geometric surrogate volumes for cardiac organs at risk can yield better contouring agreement than anatomical definitions, but retain limitations for small structures like the pulmonary valve.



1993 ◽  
Vol 49 (11) ◽  
pp. 1858-1864
Author(s):  
JUNICHI SASAKI ◽  
KIYOSHI HATA ◽  
KAZUO IZAWA ◽  
KIYOTO KAWANABE




1992 ◽  
Vol 48 (2) ◽  
pp. 251
Author(s):  
Junichi Sasaki ◽  
Kiyoshi Hata ◽  
Kazuo Izawa ◽  
Kiyoto Kawanabe


1992 ◽  
Vol 48 (8) ◽  
pp. 1358
Author(s):  
takeo mizutani ◽  
yukio uchiyama


Sign in / Sign up

Export Citation Format

Share Document