Polyethylene glycol and silica sol penetration improves hydrophobicity and dimensional stability of wood after a short-time treatment

Author(s):  
Jun Jiang ◽  
Yujie Zhou ◽  
Changtong Mei ◽  
Jinzhen Cao
Endocrinology ◽  
2010 ◽  
Vol 151 (6) ◽  
pp. 2453-2461 ◽  
Author(s):  
Maria Chiara Zatelli ◽  
Erica Gentilin ◽  
Fulvia Daffara ◽  
Federico Tagliati ◽  
Giuseppe Reimondo ◽  
...  

Mitotane therapy is associated with many side effects, including thyroid function perturbations mimicking central hypothyroidism, possibly due to laboratory test interference or pituitary direct effects of mitotane. We investigated whether increasing concentrations of mitotane in the therapeutic range might interfere with thyroid hormone assays and evaluated the effects of mitotane on a mouse TSH-producing pituitary cell line. TSH, free T4, and free T3 levels do not significantly change in sera from hypo-, hyper-, or euthyroid patients after addition of mitotane at concentrations in the therapeutic window. In the mouse TαT1 cell line, mitotane inhibits both TSH expression and secretion, blocks TSH response to TRH, and reduces cell viability, inducing apoptosis at concentrations in the therapeutic window. TRH is not capable of rescuing TαT1 cells from the inhibitory effects of mitotane on TSH expression and secretion, which appear after short time treatment and persist over time. Our results demonstrate that mitotane does not interfere with thyroid hormone laboratory tests but directly reduces both secretory activity and cell viability on pituitary TSH-secreting mouse cells. These data represent a possible explanation of the biochemical picture consistent with central hypothyroidism in patients undergoing mitotane therapy and open new perspectives on the direct pituitary effects of this drug.


2019 ◽  
Vol 43 (1) ◽  
Author(s):  
Aruna Jyothi Kora

Abstract Background In India, the sand roasting technique is widely used by street food vendors, villagers and cottage industries for making various value-added food products from different cereals, millets and legumes. The traditionally produced sand-roasted products are commonly utilized as ready to eat snacks or for the preparation of various other snacks. Results During the high-temperature short-time treatment of sand roasting, the produced products are bestowed with characteristics such as higher puffing, crispiness, volume, and improved color, aroma, flavor and texture. In terms of nutrition, the roasting process enhances the carbohydrate and protein digestibility, β-glucan extractability, levels of dietary fiber, minerals, and antioxidants and reduces the inherent antinutrients levels in cereals and legumes. In addition, the complete destruction of seed microflora enhances the shelf life and thus consumer acceptance. The sand-roasted products act as prebiotic dietary fiber and serves as an alternative to polished grains for the consumers. Thus, the simplest, inexpensive, traditional sand roasting method of dry heat application is used for making precooked ready to eat weaning foods and preparation of cost-effective dietary pediatric and geriatric formulations. The technique is also employed for roasting various beans, fryums, nut, and pulse decortication and as a pretreatment process for tamarind kernel powder production, while the sand baking method is widely used for baking cakes, vegetables, meat, fish, eggs and starchy tubers. Conclusions The techniques of sand roasting and baking are gaining importance as cheap, effective, oil-free, healthier ways of cooking. However, further studies are needed on micronutrient availability and functional food development for community nutritional disorders. Also, the residual silica levels and difficult working environment mandates the development of energy-efficient and high-output-orientated technologies such as continuous, microwave, and fluidized bed roasters.


2018 ◽  
Vol 6 ◽  
Author(s):  
Daniel Klotz ◽  
Marie Schreiner ◽  
Valeria Falcone ◽  
Daniel Jonas ◽  
Mirjam Kunze ◽  
...  

Holzforschung ◽  
2016 ◽  
Vol 70 (10) ◽  
pp. 919-926 ◽  
Author(s):  
Youming Dong ◽  
Kaili Wang ◽  
Yutao Yan ◽  
Shifeng Zhang ◽  
Jianzhang Li

Abstract Polyethylene glycol (PEG) treatment is an effective approach to endow wood with higher dimensional stability (DS), which is still a concern under humid conditions. In this study, poplar wood was first treated with methacryloyl chloride to introduce methacryl groups in the cell wall. Then functional PEG served as modifier, and copolymerization was conducted in the second step to prepare PEG-diacrylate (PEGDA) modified samples. The resultant wood polymer composites (WPCs) were characterized by solid state NMR, field emission scanning electron microscopy (FE-SEM), and X-ray diffraction (XRD). The physical and mechanical properties of the WPCs were also evaluated, such as anti-swelling efficiency (ASE), water uptake, dynamic hydrophilicity (contact angles), and thermal stability. The results show that the copolymerized WPC achieved 51.4% ASE with leaching <3.0%. Moreover, the surface hardness and water resistance of the wood are also greatly improved.


2020 ◽  
Vol 10 (8) ◽  
pp. 2649 ◽  
Author(s):  
Momoh A. Mumuni ◽  
Ugwu E. Calister ◽  
Nafiu Aminu ◽  
Kenechukwu C. Franklin ◽  
Adedokun Musiliu Oluseun ◽  
...  

In this study, different ratios of mucin-grafted polyethylene-glycol-based microparticles were prepared and evaluated both in vitro and in vivo as carriers for the oral delivery of insulin. Characterization measurements showed that the insulin-loaded microparticles display irregular porosity and shape. The encapsulation efficiency and loading capacity of insulin were >82% and 18%, respectively. The release of insulin varied between 68% and 92% depending on the microparticle formulation. In particular, orally administered insulin-loaded microparticles resulted in a significant fall of blood glucose levels, as compared to insulin solution. Subcutaneous administration showed a faster, albeit not sustained, glucose fall within a short time as compared to the polymeric microparticle-based formulations. These results indicate the possible oral delivery of insulin using this combination of polymers.


1971 ◽  
Vol 26 (6) ◽  
pp. 585-588 ◽  
Author(s):  
H. Gimmler ◽  
M. Avron

Short time treatment of intact Porphyridium cruentum cells with benzoquinone results in changes of the cell membranes, which lead to a higher permeability. This increased permeability allows the measurements of photosynthetic electron transport reactions with various electron donors, ac. ceptors and mediators, which cannot enter untreated cells. The capacity of benzoquinone to act as a Hill - reagent in vivo is interpreted as due to a double action of this compound: changing the permeability of the cells by reacting with the cell membrane coupled with the ability of the unreacted molecules to serve as electron acceptors.


2017 ◽  
Vol 89 (18) ◽  
pp. 9953-9960 ◽  
Author(s):  
Patrick Floris ◽  
Nicola McGillicuddy ◽  
Simone Albrecht ◽  
Brian Morrissey ◽  
Christian Kaisermayer ◽  
...  

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