Simultaneous optimization approach for combined control–structural design versus the conventional sequential optimization method

2020 ◽  
Author(s):  
Arsalan Alavi ◽  
Mohammad Dolatabadi ◽  
Javad Mashhadi ◽  
Ehsan Noroozinejad Farsangi
Keyword(s):  
Structural Design ◽  
Optimization Method ◽  
Simultaneous Optimization ◽  
Sequential Optimization ◽  
Optimization Approach ◽  
Combined Control

scholarly journals Co-Design of an Active Suspension Using Simultaneous Dynamic Optimization

2014 ◽  
Vol 136 (8) ◽  
Author(s):  
James T. Allison ◽  
Tinghao Guo ◽  
Zhi Han
Keyword(s):  
Dynamic Optimization ◽  
Active Suspension ◽  
Design Methods ◽  
Physical Design ◽  
Simultaneous Optimization ◽  
Sequential Optimization ◽  
Optimization Approach ◽  
Active System ◽  
Direct Transcription ◽  
Design Component

Design of physical systems and associated control systems are coupled tasks; design methods that manage this interaction explicitly can produce system-optimal designs, whereas conventional sequential processes may not. Here, we explore a new technique for combined physical and control system design (co-design) based on a simultaneous dynamic optimization approach known as direct transcription, which transforms infinite-dimensional control design problems into finite-dimensional nonlinear programming problems. While direct transcription problem dimension is often large, sparse problem structures and fine-grained parallelism (among other advantageous properties) can be exploited to yield computationally efficient implementations. Extension of direct transcription to co-design gives rise to new problem structures and new challenges. Here, we illustrate direct transcription for co-design using a new automotive active suspension design example developed specifically for testing co-design methods. This example builds on prior active suspension problems by incorporating a more realistic physical design component that includes independent design variables and a broad set of physical design constraints, while maintaining linearity of the associated differential equations. A simultaneous co-design approach was implemented using direct transcription, and numerical results were compared with conventional sequential optimization. The simultaneous optimization approach achieves better performance than sequential design across a range of design studies. The dynamics of the active system were analyzed with varied level of control authority to investigate how dynamic systems should be designed differently when active control is introduced.

The Application of the Combination of Monte Carlo Optimization Method based QSAR Modeling and Molecular Docking in Drug Design and Development

2020 ◽  
Vol 20 (14) ◽  
pp. 1389-1402 ◽  
Author(s):  
Maja Zivkovic ◽  
Marko Zlatanovic ◽  
Nevena Zlatanovic ◽  
Mladjan Golubović ◽  
Aleksandar M. Veselinović
Keyword(s):  
Monte Carlo ◽  
Molecular Docking ◽  
Computer Calculation ◽  
Molecular Graph ◽  
Optimization Method ◽  
Docking Studies ◽  
Optimization Approach ◽  
Qsar Modeling ◽  
Monte Carlo Optimization ◽  
Molecular Docking Studies

In recent years, one of the promising approaches in the QSAR modeling Monte Carlo optimization approach as conformation independent method, has emerged. Monte Carlo optimization has proven to be a valuable tool in chemoinformatics, and this review presents its application in drug discovery and design. In this review, the basic principles and important features of these methods are discussed as well as the advantages of conformation independent optimal descriptors developed from the molecular graph and the Simplified Molecular Input Line Entry System (SMILES) notation compared to commonly used descriptors in QSAR modeling. This review presents the summary of obtained results from Monte Carlo optimization-based QSAR modeling with the further addition of molecular docking studies applied for various pharmacologically important endpoints. SMILES notation based optimal descriptors, defined as molecular fragments, identified as main contributors to the increase/ decrease of biological activity, which are used further to design compounds with targeted activity based on computer calculation, are presented. In this mini-review, research papers in which molecular docking was applied as an additional method to design molecules to validate their activity further, are summarized. These papers present a very good correlation among results obtained from Monte Carlo optimization modeling and molecular docking studies.

scholarly journals Sequential Optimization Method for the Design of Electromagnetic Device

2008 ◽  
Vol 44 (11) ◽  
pp. 3217-3220 ◽  
Author(s):  
Gang Lei ◽  
K.R. Shao ◽  
Youguang Guo ◽  
Jianguo Zhu ◽  
J.D. Lavers
Keyword(s):  
Optimization Method ◽  
Sequential Optimization ◽  
Electromagnetic Device

Control Proxy Functions for Sequential Design and Control Optimization

2011 ◽  
Vol 133 (9) ◽  
Author(s):  
Diane L. Peters ◽  
P. Y. Papalambros ◽  
A. G. Ulsoy
Keyword(s):  
Simultaneous Optimization ◽  
Sequential Optimization ◽  
Control Optimization ◽  
Smart Products ◽  
System Solution ◽  
Optimal System Design ◽  
Problem Formulations ◽  
And Control ◽  
Sequential Strategy ◽  
Selection Of

Optimal system design of “smart” products requires optimization of both the artifact and its controller. When the artifact and the controller designs are independent, the system solution is straightforward through sequential optimization. When the designs are coupled, combined simultaneous optimization can produce system-optimal results, but presents significant computational and organizational complexity. This paper presents a method that produces results comparable with those found with a simultaneous solution strategy, but with the simplicity of the sequential strategy. The artifact objective function is augmented by a control proxy function (CPF), representing the artifact’s ease of control. The key to successful use of this method is the selection of an appropriate CPF. Four theorems that govern the choice and evaluation of a CPF are given. Each theorem is illustrated using a simple mathematical example. Specific CPFs are then presented for particular problem formulations, and the method is applied to the optimal design and control of a micro-electrical mechanical system actuator.

scholarly journals A two-stage evolutionary optimization approach for an irrigation system design

2016 ◽  
Vol 19 (1) ◽  
pp. 115-122 ◽  
Author(s):  
Milan Cisty ◽  
Zbynek Bajtek ◽  
Lubomir Celar
Keyword(s):  
Water Distribution ◽  
Irrigation System ◽  
Optimal Solution ◽  
Water Distribution Network ◽  
Search Space ◽  
Optimization Method ◽  
Global Optimum ◽  
Optimization Approach ◽  
Nsga Ii ◽  
Irrigation Network

In this work, an optimal design of a water distribution network is proposed for large irrigation networks. The proposed approach is built upon an existing optimization method (NSGA-II), but the authors are proposing its effective application in a new two-step optimization process. The aim of the paper is to demonstrate that not only is the choice of method important for obtaining good optimization results, but also how that method is applied. The proposed methodology utilizes as its most important feature the ensemble approach, in which more optimization runs cooperate and are used together. The authors assume that the main problem in finding the optimal solution for a water distribution optimization problem is the very large size of the search space in which the optimal solution should be found. In the proposed method, a reduction of the search space is suggested, so the final solution is thus easier to find and offers greater guarantees of accuracy (closeness to the global optimum). The method has been successfully tested on a large benchmark irrigation network.

A fast multiobjective optimization approach to S-duct scoop inlets design with both inflow and outflow

2018 ◽  
Vol 233 (9) ◽  
pp. 3381-3394
Author(s):  
Lifang Zeng ◽  
Dingyi Pan ◽  
Shangjun Ye ◽  
Xueming Shao
Keyword(s):  
Multiobjective Optimization ◽  
Total Pressure ◽  
Optimization Method ◽  
Navier Stokes ◽  
Integral Model ◽  
Optimization Approach ◽  
Navier Stokes Equation ◽  
Cross Sectional ◽  
Design Variables ◽  
Computational Fluid Dynamics Analysis

A fast multiobjective optimization method for S-duct scoop inlets considering both inflow and outflow is developed and validated. To reduce computation consumption of optimization, a simplified efficient model is proposed, in which only inflow region is simulated. Inlet pressure boundary condition of the efficient model is specified by solving an integral model with both inflow and outflow. An automated optimization system integrating the computational fluid dynamics analysis, nonuniform rational B-spline geometric representation technique, and nondominated sorting genetic algorithm II is developed to minimize the total pressure loss and distortion at the exit of diffuser. Flow field is numerically simulated by solving the Reynolds-averaged Navier–Stokes equation coupled with k–ω shear stress transport turbulence model, and results are validated to agree well with previous experiment. S-duct centreline shape and cross-sectional area distribution are parameterized as the design variables. By analyzing the results of a suggested optimal inlet chosen from the obtained Pareto front, total pressure recovery has increased from 97% to 97.4%, and total pressure distortion DC60 has decreased by 0.0477 (21.7% of the origin) at designed Mach number 0.7. The simplified efficient model has been validated to be reliable, and by which the time cost for the optimization project has been reduced by 70%.

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