Association between bone mineral density, muscle strength, and vitamin D status in patients with myasthenia gravis: a cross-sectional study

2017 ◽  
Vol 28 (8) ◽  
pp. 2383-2390 ◽  
Author(s):  
Y. Guan ◽  
F. Lv ◽  
Y. Meng ◽  
D. Ma ◽  
X. Xu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Muscle Strength ◽  
Myasthenia Gravis ◽  
Bone Mineral ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

scholarly journals Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Emma T. Callegari ◽  
Nicola Reavley ◽  
Suzanne M. Garland ◽  
Alexandra Gorelik ◽  
John D. Wark ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mineral ◽  
Young Women ◽  
Bone Health ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

<em>Background</em>. Vitamin D deficiency has been associated with both poor bone health and mental ill-health. More recently, a number of studies have found individuals with depressive symptoms tend to have reduced bone mineral density. To explore the interrelationships between vitamin D status, bone mineral density and mental-ill health we are assessing a range of clinical, behavioural and lifestyle factors in young women (Part A of the Safe-D study). <br /><em>Design and methods.</em> Part A of the Safe-D study is a cross-sectional study aiming to recruit 468 young females aged 16-25 years living in Victoria, Australia, through Facebook advertising. Participants are required to complete an extensive, online questionnaire, wear an ultra-violet dosimeter for 14 consecutive days and attend a study site visit. Outcome measures include areal bone mineral measures at the lumbar spine, total hip and whole body, as well as soft tissue composition using dual energy x-ray absorptiometry. Trabecular and cortical volumetric bone density at the tibia is measured using peripheral quantitative computed tomography. Other tests include serum 25-hydroxyvitamin D, serum biochemistry and a range of health markers. Details of mood disorder/s and depressive and anxiety symptoms are obtained by self-report. Cutaneous melanin density is measured by spectrophotometry. <br /><em>Expected impact.</em> The findings of this cross-sectional study will have implications for health promotion in young women and for clinical care of those with vitamin D deficiency and/or mental ill-health. Optimising both vitamin D status and mental health may protect against poor bone health and fractures in later life.

scholarly journals Muscle strength and areal bone mineral density at the hip in women: a cross-sectional study

2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Julie A. Pasco ◽  
Kara L. Holloway ◽  
Sharon L. Brennan-Olsen ◽  
David J. Moloney ◽  
Mark A. Kotowicz
Keyword(s):  
Bone Mineral Density ◽  
Muscle Strength ◽  
Bone Mineral ◽  
Cross Sectional Study ◽  
Areal Bone Mineral Density ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

scholarly journals Bone mineral density and its correlation with Vitamin D status in healthy adults of Manipur – A cross-sectional study

2020 ◽  
pp. 6-9
Author(s):  
Dr karthika M ◽  
Prakash Chandra Bhardwaj ◽  
Laimayum Amarnath Sharma ◽  
W Kanan ◽  
W Asoka Singh
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mass ◽  
Enzyme Immunoassay ◽  
Bone Mineral ◽  
Healthy Adult ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

The levels of vitamin D have an important effect on bone mass in young and old. Hypovitaminosis D adversely affects calcium metabolism, osteoblastic activity, matrix ossification, bone remodeling, and hence bone density. Objective: The present study was conducted to determine the status of serum 25(OH)D and BMD of healthy adult men in Manipur and also to find out the relationship of 25(OH)D level with BMD. Methods: A cross-sectional study was conducted in Department of Physiology in collaboration with the Department of Physical Medicine & Rehabilitation, Regional Institute of Medical Sciences (RIMS), Imphal from October 2014 to September 2016. 100 Healthy adult males in Manipur in the age group 18-35years and ≥50years were included in the study after obtaining Ethical approval from the Research Ethics Board, RIMS, Imphal. The serum 25-OH vitamin D level was estimated by using an enzyme immunoassay (EIA) kit (IDS immunodiagnostic systems, United Kingdom). The BMD of lumbar spine was determined using enCORE – based X-ray bone densitometer (Lunar Prodigy advance, GE Medical Systems, USA) which is based on DEXA scan. Results: The present study revealed that the majority of subjects with insufficiency of 25(OH)D had low bone mass, whereas all the subjects with 25(OH)D deficiency had BMD readings consistent with osteopenia or osteoporosis in both the age groups. This study also showed a positive correlation between BMD and 25(OH)D in most subjects, particularly in the groups with insufficiency or deficiency of 25(OH)D.Conclusion: In conclusion, the study shows a positive relationship between the serum 25 (OH) D concentrations and BMD. Keywords: Serum 25(OH)D; Bone mineral density (BMD); Enzyme immunoassay (EIA).

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