Vitamin D status and PTH in young men: a cross-sectional study on associations with bone mineral density, body composition and glucose metabolism

2010 ◽  
Vol 73 (5) ◽  
pp. 573-580 ◽  
Author(s):  
M. Frost ◽  
B. Abrahamsen ◽  
T.L. Nielsen ◽  
C. Hagen ◽  
M. Andersen ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Body Composition ◽  
Glucose Metabolism ◽  
Bone Mineral ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

scholarly journals Vitamin D status, bone mineral density and mental health in young Australian women: the Safe-D study

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Emma T. Callegari ◽  
Nicola Reavley ◽  
Suzanne M. Garland ◽  
Alexandra Gorelik ◽  
John D. Wark ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mineral ◽  
Young Women ◽  
Bone Health ◽  
Cross Sectional Study ◽  
Vitamin D Status ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

<em>Background</em>. Vitamin D deficiency has been associated with both poor bone health and mental ill-health. More recently, a number of studies have found individuals with depressive symptoms tend to have reduced bone mineral density. To explore the interrelationships between vitamin D status, bone mineral density and mental-ill health we are assessing a range of clinical, behavioural and lifestyle factors in young women (Part A of the Safe-D study). <br /><em>Design and methods.</em> Part A of the Safe-D study is a cross-sectional study aiming to recruit 468 young females aged 16-25 years living in Victoria, Australia, through Facebook advertising. Participants are required to complete an extensive, online questionnaire, wear an ultra-violet dosimeter for 14 consecutive days and attend a study site visit. Outcome measures include areal bone mineral measures at the lumbar spine, total hip and whole body, as well as soft tissue composition using dual energy x-ray absorptiometry. Trabecular and cortical volumetric bone density at the tibia is measured using peripheral quantitative computed tomography. Other tests include serum 25-hydroxyvitamin D, serum biochemistry and a range of health markers. Details of mood disorder/s and depressive and anxiety symptoms are obtained by self-report. Cutaneous melanin density is measured by spectrophotometry. <br /><em>Expected impact.</em> The findings of this cross-sectional study will have implications for health promotion in young women and for clinical care of those with vitamin D deficiency and/or mental ill-health. Optimising both vitamin D status and mental health may protect against poor bone health and fractures in later life.

scholarly journals Bone mineral density and its correlation with Vitamin D status in healthy adults of Manipur – A cross-sectional study

2020 ◽  
pp. 6-9
Author(s):  
Dr karthika M ◽  
Prakash Chandra Bhardwaj ◽  
Laimayum Amarnath Sharma ◽  
W Kanan ◽  
W Asoka Singh
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Bone Mass ◽  
Enzyme Immunoassay ◽  
Bone Mineral ◽  
Healthy Adult ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

The levels of vitamin D have an important effect on bone mass in young and old. Hypovitaminosis D adversely affects calcium metabolism, osteoblastic activity, matrix ossification, bone remodeling, and hence bone density. Objective: The present study was conducted to determine the status of serum 25(OH)D and BMD of healthy adult men in Manipur and also to find out the relationship of 25(OH)D level with BMD. Methods: A cross-sectional study was conducted in Department of Physiology in collaboration with the Department of Physical Medicine & Rehabilitation, Regional Institute of Medical Sciences (RIMS), Imphal from October 2014 to September 2016. 100 Healthy adult males in Manipur in the age group 18-35years and ≥50years were included in the study after obtaining Ethical approval from the Research Ethics Board, RIMS, Imphal. The serum 25-OH vitamin D level was estimated by using an enzyme immunoassay (EIA) kit (IDS immunodiagnostic systems, United Kingdom). The BMD of lumbar spine was determined using enCORE – based X-ray bone densitometer (Lunar Prodigy advance, GE Medical Systems, USA) which is based on DEXA scan. Results: The present study revealed that the majority of subjects with insufficiency of 25(OH)D had low bone mass, whereas all the subjects with 25(OH)D deficiency had BMD readings consistent with osteopenia or osteoporosis in both the age groups. This study also showed a positive correlation between BMD and 25(OH)D in most subjects, particularly in the groups with insufficiency or deficiency of 25(OH)D.Conclusion: In conclusion, the study shows a positive relationship between the serum 25 (OH) D concentrations and BMD. Keywords: Serum 25(OH)D; Bone mineral density (BMD); Enzyme immunoassay (EIA).

scholarly journals Sex-specific and age-specific characteristics of body composition and its effect on bone mineral density in adults in southern China: a cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. e032268
Author(s):  
Zeyu Xiao ◽  
Zhiqiang Tan ◽  
Jingjie Shang ◽  
Yong Cheng ◽  
Yongjin Tang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Linear Regression ◽  
Bone Mineral ◽  
Lean Mass ◽  
Cross Sectional Study ◽  
Whole Body ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

ObjectivesThis study was an attempt to investigate the variation trend of body composition with ageing and explore the association between regional body composition and bone mineral density (BMD).DesignCross-sectional study.Setting and participantsA total of 5749 healthy adults aged 20–95 years was recruited from 2004 to 2017.Primary outcome measuresWhole-body lean mass (LM), fat mass (FM), android FM, gynoid FM, appendicular lean mass (ALM) and BMD in the lumbar spine, femoral neck and total hip were obtained by dual-energy X-ray absorptiometry (DXA). The android/gynoid fat mass ratio (A/G FMR) based on DXA scan was calculated as an indicator of adipose distribution. Pearson correlation and multiple linear regression analyses were used to determine the associations between body composition, adipose distribution, and BMD of each skeletal site.ResultsWhole-body FM, percentage of whole-body FM, Android FM and A/G FMR consistently increased with age in both genders, especially in women, and ALM began to decrease in the fifth decade for both men and women. In multivariable linear regression models with age, body mass index, A/G FMR and ALM as predictor variables, ALM was associated with the most BMD variance of all skeletal sites in men (standard β ranged from 0.207 to 0.405, p<0.001), although not the largest but still a positive predictor of BMD in women (standard β ranged from 0.074 to 0.186, p<0.05). A/G FMR was an inverse predictor of BMD at all skeletal sites for women (standard β ranged from −249 to −0.052, p<0.01) but not in men.ConclusionsIn this large cohort of Chinese adults, ALM had a strong positive association with BMD in both genders. A/G FMR as an indicator of central adipose accumulation was inversely associated with BMD in women but not in men.

Bone mineral density in immigrants from southern China to Denmark. A cross-sectional study

1996 ◽  
Vol 134 (2) ◽  
pp. 163-167 ◽  
Author(s):  
Q Wang ◽  
P Ravn ◽  
S Wang ◽  
K Overgaard ◽  
C Hassager ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Bone Mass ◽  
Bone Mineral ◽  
Southern China ◽  
Premenopausal Women ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional

Wang Q, Ravn P, Wang S, Overgaard K, Hassager C, Christiansen C. Bone mineral density in immigrants from southern China to Denmark: a cross-sectional study. Eur J Endocrinol 1996;134:163–7. ISSN 0804–4643 Immigration from Japan to USA has been shown to increase bone mineral density (BMD) and body fat in women. The effects of immigration between other geographical areas on bone mass and body composition are largely unknown, especially in men. In the present study, we measured bone mass and body composition by dual energy X-ray absorptiometry (Hologic QDR-2000) in 73 healthy premenopausal women (age 35 ± 8 years) and 69 men (age 40 ± 12 years) who had immigrated from southern China to Denmark 2 months to 36 years ago. The BMD measurements (Total BMD, trunk BMD and leg BMD) were related positively to years since immigration (YSI) (R2 = 0.10–0.16, p < 0.05) in premenopausal women, but not in men. Fat distribution was related mainly to age in both premenopausal women and men (R2 = 0.16–0.26, p < 0.05). For comparison, we included 51 white, Danish premenopausal women (age 36 ± 6 years). Chinese premenopausal women with a YSI below or equal to 12 years (N = 38) had significantly lower total and regional BMD (trunk, legs, arms) (p < 0.05), while women with a YSI above 12 years (N = 35) had significantly lower BMD in the legs only (p < 0.05) when compared to the Danish premenopausal women. After correction for age, weight and height, Chinese premenopausal women with a YSI below or equal to 12 years still had significantly lower BMD in all regions (4–7%, p < 0.05), whereas no differences in BMD were found between Chinese premenopausal women with a YSI above 12 years compared with Danish premenopausal women. In conclusion, Chinese premenopausal women who immigrated to Denmark more than 12 years ago have a similar BMD to that of Danish premenopausal women. In the group who immigrated less than 12 years ago, a significantly lower BMD was found. P Ravn, Center for Clinical and Basic Research, Ballerup Byvej 222, DK-2750 Ballerup, Denmark

Sign in / Sign up

Export Citation Format

Share Document