Gene expression profiles of T lymphocytes are sensitive to the influence of heavy smoking: a pilot study

2006 ◽  
Vol 59 (1) ◽  
pp. 37-43 ◽  
Author(s):  
Petra Büttner ◽  
Sandy Mosig ◽  
Harald Funke
Keyword(s):  
Gene Expression ◽  
Pilot Study ◽  
T Lymphocytes ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Heavy Smoking

Distinct gene expression profiles between human preterm-derived and adult-derived intestinal organoids exposed to Enterococcus faecalis: a pilot study

Gut ◽  
2021 ◽  
pp. gutjnl-2021-326552
Author(s):  
Andrea C Masi ◽  
Tatiana Y Fofanova ◽  
Christopher A Lamb ◽  
Jennifer M Auchtung ◽  
Robert A Britton ◽  
...  
Keyword(s):  
Gene Expression ◽  
Pilot Study ◽  
Enterococcus Faecalis ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Distinct Gene ◽  
Intestinal Organoids

scholarly journals Gene expression analyses on multi-target mode of action of black cohosh in menopausal complaints – a pilot study in rodents

2021 ◽  
Author(s):  
Petra Stute ◽  
S. Ehrentraut ◽  
H.-H. Henneicke-von Zepelin ◽  
P. Nicken
Keyword(s):  
Gene Expression ◽  
Pilot Study ◽  
Mode Of Action ◽  
Hormonal Regulation ◽  
Expression Profiles ◽  
Hot Flashes ◽  
Gene Expression Profiles ◽  
Black Cohosh ◽  
Sprague Dawley ◽  
Ovx Rats

Abstract Purpose This study aimed at assessing gene expression profiles in hippocampus and hypothalamus of ovariectomized (OVX) rats with or without treatment with an isopropanolic extract of Cimicifuga racemosa rhizomes (iCR) in comparison to intact rats. Methods Exploration of hippocampal (Hi) and hypothalamic (Hy) tissue from Sprague Dawley rats: without OVX (NHi = NHy = 4), tissues 3 months after OVX (NHi = 4, NHy = 3), or tissues of rats after their treatment with iCR for 3 months after OVX (NHi = NHy = 2). Gene expression profiles in these tissues were investigated by RNA-microarray-analysis and subsequent verification by qPCR. Results 4812 genes were differentially regulated when comparing the three groups in hippocampus and hypothalamus. iCR compensated the effects of OVX in 518 genes. This compensatory effect was most prominent in hippocampal signalling pathways, thereof genes (GAL, CALCA, HCRT, AVPR1A, PNOC, etc.) involved in thermoregulation, regulation of sleep and arousal, blood pressure regulation, metabolism, nociception, hormonal regulation, homeostasis, learning and cognition, mood regulation, neuroendocrine modulation, etc.. In the hypothalamus, iCR compensated OVX-effects at TAC3 and OPRM1 but not at KISS1. These genes are involved in the pathophysiology of hot flashes. Conclusions Our pilot study findings support a multifaceted mode of action of iCR in menopausal complaints on a tissue-specific brain gene expression level.

Pilot study to evaluate gene expression profiles of circulating cells in shift workers with and without breast cancer

2017 ◽  
Vol 40 ◽  
pp. e10
Author(s):  
A. Alisi ◽  
R. Brugaletta ◽  
A.P. Santoro ◽  
N. Panera ◽  
G. Dalmasso ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Pilot Study ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Shift Workers ◽  
Circulating Cells

Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study

Biomarkers ◽  
2003 ◽  
Vol 8 (1) ◽  
pp. 51-61 ◽  
Author(s):  
Laurie A. Davidson ◽  
Joanne R. Lupton ◽  
Emil Miskovsky ◽  
Alan P. Fields ◽  
Robert S. Chapkin
Keyword(s):  
Gene Expression ◽  
Pilot Study ◽  
Expression Profiles ◽  
Gene Expression Profiles

1327: Gene Expression Profiles in Benign Prostatic Hyperplasia

2004 ◽  
Vol 171 (4S) ◽  
pp. 349-350
Author(s):  
Gaelle Fromont ◽  
Michel Vidaud ◽  
Alain Latil ◽  
Guy Vallancien ◽  
Pierre Validire ◽  
...  
Keyword(s):  
Gene Expression ◽  
Benign Prostatic Hyperplasia ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Prostatic Hyperplasia
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