Biogenic synthesis of metal nanoparticles from actinomycetes: biomedical applications and cytotoxicity

2014 ◽  
Vol 98 (19) ◽  
pp. 8083-8097 ◽  
Author(s):  
Patrycja Golinska ◽  
Magdalena Wypij ◽  
Avinash P. Ingle ◽  
Indarchand Gupta ◽  
Hanna Dahm ◽  
...  
Keyword(s):  
Metal Nanoparticles ◽  
Biomedical Applications ◽  
Biogenic Synthesis

Review on Methodologies Used in the Synthesis of Metal Nanoparticles: Significance of Phytosynthesis Using Plant Extract as an Emerging Tool

2020 ◽  
Vol 26 (40) ◽  
pp. 5188-5204
Author(s):  
Uzair Nagra ◽  
Maryam Shabbir ◽  
Muhammad Zaman ◽  
Asif Mahmood ◽  
Kashif Barkat
Keyword(s):  
Green Synthesis ◽  
Metal Nanoparticles ◽  
Plant Extracts ◽  
Biomedical Applications ◽  
Noble Metals ◽  
Cost Effective ◽  
Green Technology ◽  
Critical Parameters ◽  
Nanosized Particles ◽  
Preparation Methods

Nanosized particles, with a size of less than 100 nm, have a wide variety of applications in various fields of nanotechnology and biotechnology, especially in the pharmaceutical industry. Metal nanoparticles [MNPs] have been synthesized by different chemical and physical procedures. Still, the biological approach or green synthesis [phytosynthesis] is considered as a preferred method due to eco-friendliness, nontoxicity, and cost-effective production. Various plants and plant extracts have been used for the green synthesis of MNPs, including biofabrication of noble metals, metal oxides, and bimetallic combinations. Biomolecules and metabolites present in plant extracts cause the reduction of metal ions into nanosized particles by one-step preparation methods. MNPs have remarkable attractiveness in biomedical applications for their use as potential antioxidant, anticancer and antibacterial agents. The present review offers a comprehensive aspect of MNPs production via top-to-bottom and bottom-to-top approach with considerable emphasis on green technology and their possible biomedical applications. The critical parameters governing the MNPs formation by plant-based synthesis are also highlighted in this review.

Hyperthermic Cytotoxicity Induced by Noninvasive Radiofrequency Field Exposure After Delivery of EGFR Family Targeted Gold Nanoparticles

2010 ◽  
Author(s):  
Evan S. Glazer ◽  
Warna D. Kaluarachchi ◽  
Steven A. Curley
Keyword(s):  
Flow Cytometry ◽  
Gold Nanoparticles ◽  
Metal Nanoparticles ◽  
Biomedical Applications ◽  
Carcinoma Cells ◽  
Field Exposure ◽  
Radiofrequency Field ◽  
Hep3b Cells ◽  
Egfr Family ◽  
Similar Decrease

Noninvasive radiofrequency (RF) fields heat metal nanoparticles in a concentration dependent fashion. Gold nanoparticles are especially interesting for biomedical applications because they not only heat well, but they have an established biosafety profile. Antibody-targeted gold nanoparticles have been used to induce hyperthermic cytotoxicity when exposed to RF fields. Two carcinoma cells lines, Panc-1 and Hep3B, were individually treated with 100 nM panitumumab and trastuzumab antibody conjugated 10 nm gold nanoparticles and subsequently exposed to an RF field for a total generator power of ∼100 kJ. Two days later, control cells treated with antibody labeled gold nanoparticles, but not exposed to the RF field, maintained an average viability of 92.1% ± 2.5% for Hep 3B cells and 89.1% ± 2.1% for Panc-1 cells based on flow cytometry. Panc-1 cells treated the same way with subsequent RF field exposure had viability less than 80% (p ∼ 0.001). Hep3B cells showed a similar decrease in viability after trastuzumab-gold treatment (74.5% ± 6.9%), but not panitumumab. This demonstrates a new and developing use of antibodies, specifically, against EGFR family targets.

scholarly journals GREEN SYNTHESIS OF PLANT-MEDIATED METAL NANOPARTICLES: THE ROLE OF POLYPHENOLS

2019 ◽  
pp. 75-84 ◽  
Author(s):  
LATIF MS ◽  
ABBAS S ◽  
KORMIN F ◽  
MUSTAFA MK
Keyword(s):  
Metal Nanoparticles ◽  
Biomedical Applications ◽  
Cost Effective ◽  
Metal Salts ◽  
Chemical Methods ◽  
Physical And Chemical ◽  
Labor Consuming ◽  
Day By Day ◽  
Biological Actions

The use of metal nanoparticles (MNPs) in various fields is increasing day-by-day leading to a genuine concern about the issues related to their environmental and biological safety. The major approaches for the synthesis of NPs include physical and chemical methods which are expensive and hazardous to health in addition to being toxic to the environment. This review highlights the potential of plant extracts to carry out the synthesis of MNPs with a special emphasis on the role of flavonoids in nanosynthesis. This green and clean approach have been actively utilized in recent years as an alternative to conventional hazardous approaches. It has proved as cost-effective, non-toxic, less time and labor consuming, efficient, and eco-friendly method for the synthesis of MNPs with specific biological actions. This review also focuses on the role of polyphenols, including the flavonoids as bioreductants of metal salts for the synthesis of NPs along with their biomedical applications. Various examples of the MNPs, along with their biological actions, have also been summarized.

scholarly journals Biogenic Synthesis of Metal Nanoparticles Using a Biosurfactant Extracted from Corn and Their Antimicrobial Properties

Nanomaterials ◽  
2017 ◽  
Vol 7 (6) ◽  
pp. 139 ◽  
Author(s):  
Sergio Gómez-Graña ◽  
María Perez-Ameneiro ◽  
Xanel Vecino ◽  
Isabel Pastoriza-Santos ◽  
Jorge Perez-Juste ◽  
...  
Keyword(s):  
Metal Nanoparticles ◽  
Antimicrobial Properties ◽  
Biogenic Synthesis

scholarly journals Silver nanoparticles: synthesis through chemical methods in solution and biomedical applications

2011 ◽  
Vol 9 (1) ◽  
pp. 7-19 ◽  
Author(s):  
Jorge García-Barrasa ◽  
José López-de-Luzuriaga ◽  
Miguel Monge
Keyword(s):  
Wound Healing ◽  
Silver Nanoparticles ◽  
Metal Nanoparticles ◽  
Biomedical Applications ◽  
Antiviral Agent ◽  
Ag Nps ◽  
Chemical Methods ◽  
Precise Control ◽  
Nanoparticles Synthesis ◽  
Inorganic Nanomaterials

AbstractChemical methods provide an easy way to synthesize silver nanoparticles (Ag NPs) in solution. These metal nanoparticles have a great potential for biomedical applications as an antibacterial, antifungal, and antiviral agent or in wound healing. The adjustment of the parameters involved in these reactions permits a precise control over the size, shape, monodispersity, and the surfaces of the nanoparticles. These nanoparticles are being used in the design of new hybrid organic-inorganic or inorganic nanomaterials for biomedical applications.

scholarly journals Biomedical applications of plasmon resonant metal nanoparticles

Nanomedicine ◽  
2006 ◽  
Vol 1 (2) ◽  
pp. 201-208 ◽  
Author(s):  
Hongwei Liao ◽  
Colleen L Nehl ◽  
Jason H Hafner
Keyword(s):  
Metal Nanoparticles ◽  
Biomedical Applications

ChemInform Abstract: A Brief Introduction to the Development of Biogenic Synthesis of Metal Nanoparticles

ChemInform ◽  
2015 ◽  
Vol 46 (41) ◽  
pp. no-no
Author(s):  
Samiran Mondal ◽  
Saswati Basu ◽  
Naznin Ara Begum ◽  
Debabrata Mandal
Keyword(s):  
Metal Nanoparticles ◽  
Biogenic Synthesis

A Brief Introduction to the Development of Biogenic Synthesis of Metal Nanoparticles

2014 ◽  
Vol 27 ◽  
pp. 41-52 ◽  
Author(s):  
Samiran Mondal ◽  
Saswati Basu ◽  
Naznin Ara Begum ◽  
Debabrata Mandal
Keyword(s):  
Chemical Synthesis ◽  
Metal Nanoparticles ◽  
Particle Morphology ◽  
Cost Effective ◽  
Pd Nanoparticles ◽  
Attractive Alternative ◽  
Synthesis Methods ◽  
Biogenic Synthesis ◽  
Environment Friendly ◽  
Synthesis Of Nanoparticles

Though there are a numerous methods for chemical synthesis, biogenic synthesis of nanoparticles offers an attractive alternative to chemical synthesis methods. Therefore scientists are continuously engaged in searching hazard free, environment friendly methods of synthesis of nanoparticles with tailor-made structural properties using benign starting materials. Recently several groups have achieved success in the synthesis of Ag, Au, Pd nanoparticles with specific shape and size using extracts obtained from micro-organisms as well as various plant extracts. It will be a highly interesting problem to modify the procedure to develop green-chemical means of synthesizing “tailor-made” monodisperse nanoparticles of single polygonal particle morphology, exclusively. The main objective of this brief article is to give an idea about the most reliable, cost-effective and environment friendly synthetic protocols for metal nanoparticles of different size, shape, composition, and with a high degree of monodispersity.

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