Regenerative Surgery: Use of Fat Grafting Combined with Platelet-Rich Plasma for Chronic Lower-Extremity Ulcers

2009 ◽  
Vol 33 (3) ◽  
pp. 340-345 ◽  
Author(s):  
V. Cervelli ◽  
P. Gentile ◽  
M. Grimaldi
Keyword(s):  
Lower Extremity ◽  
Platelet Rich Plasma ◽  
Fat Grafting

scholarly journals Safety of Aesthetic Medicine Procedures in Patients with Autoimmune Thyroid Disease: A Literature Review

Medicina ◽  
2021 ◽  
Vol 58 (1) ◽  
pp. 30
Author(s):  
Kamil Adamczyk ◽  
Ewa Rusyan ◽  
Edward Franek
Keyword(s):  
Platelet Rich Plasma ◽  
Fat Grafting ◽  
Thyroid Diseases ◽  
Autoimmune Thyroid Diseases ◽  
Aesthetic Medicine ◽  
Autoimmune Thyroid ◽  
Wide Range ◽  
Organ Specific ◽  
Safety Studies ◽  
Potential Possibility

Autoimmune thyroid diseases are the most common organ-specific autoimmune diseases, affecting 2–5% of the world’s population. Due to the autoimmune background of thyroid diseases, we analyzed a wide range of cosmetic procedures, from minimally invasive cosmetic injections (mesotherapy) to highly invasive procedures, such as lifting threads. Out of the seven categories of treatments in aesthetic medicine analyzed by us—hyaluronic acid, botulinum toxin, autologous platelet-rich plasma, autologous fat grafting, lifting threads, IPL and laser treatment and mesotherapy—only two, mesotherapy and lifting threads, are not recommended. This is due to the lack of safety studies and the potential possibility of a higher frequency of side effects in patients with autoimmune thyroid diseases.

scholarly journals Systematic review of the efficacy of fat grafting and platelet-rich plasma for wound healing

2018 ◽  
Vol 15 (4) ◽  
pp. 519-526 ◽  
Author(s):  
Oliver J Smith ◽  
Muholan Kanapathy ◽  
Ankur Khajuria ◽  
Max Prokopenko ◽  
Nadine Hachach-Haram ◽  
...  
Keyword(s):  
Systematic Review ◽  
Wound Healing ◽  
Platelet Rich Plasma ◽  
Fat Grafting

Study of the effect of platelet rich plasma (PRP) on structural fat grafting for breast augmentation

2012 ◽  
Vol 10 (2) ◽  
pp. 755-763
Author(s):  
Asser A El-Hilaly ◽  
Sameh M El-Taher ◽  
Ahmed F El-Sherif ◽  
Mohamed H Zedan
Keyword(s):  
Breast Augmentation ◽  
Platelet Rich Plasma ◽  
Fat Grafting

scholarly journals Comparison of Allogeneic Platelet-rich Plasma With Autologous Platelet-rich Plasma for the Treatment of Diabetic Lower Extremity Ulcers

2020 ◽  
Vol 29 ◽  
pp. 096368972093142
Author(s):  
Min He ◽  
Xuewen Guo ◽  
Tao Li ◽  
Xiaoyan Jiang ◽  
Yan Chen ◽  
...  
Keyword(s):  
Wound Healing ◽  
Lower Extremity ◽  
Adverse Reactions ◽  
Chronic Wounds ◽  
Platelet Rich Plasma ◽  
Ankle Brachial Index ◽  
Nutritional Regulation ◽  
Significant Difference ◽  
Autologous Platelet Rich Plasma ◽  
Autologous Platelet

Autologous platelet-rich plasma (au-PRP) has been widely used for the management of refractory chronic wounds. However, patients with diabetic lower extremity ulcers (DLEUs) usually have complicated clinical conditions, and the utility of au-PRP is limited. In this study, the feasibility, effectiveness, and safety of allogeneic platelet-rich plasma (al-PRP) and au-PRP were investigated and compared in the treatment of DLEUs. A total of 75 in-patients with type 2 diabetes were assigned to the al-PRP group ( n = 20), au-PRP group ( n = 25), and conventional wound therapeutic (CWT) group ( n = 30) matched by the ankle brachial index and ulcer size from December 2015 to August 2018. Based on metabolic and nutritional regulation, infective control, and topical wound management, al-PRP, au-PRP, and CWT were administered to each group, respectively. Evaluation of treatment outcomes was determined by the parameters of wound healing and adverse reactions. The therapeutic times and average concentration of platelets were not significantly different between the au-PRP and al-PRP groups. The wound healing times of the al-PRP group (56.9 ± 29.22 d) and au-PRP group (55.6 ± 33.8 d) were significantly shorter than those of the CWT group (88.0 ± 43.4 d) ( P < 0.01), but there was no significant difference between the groups with PRP treatment. Although there was no significant difference in the daily healing area among all groups ( P > 0.05), the trend of the healing rate in the al-PRP group (16.77 ± 12.85 mm2), au-PRP group (14.31 ± 18.28 mm2), and CWT group (9.90 ± 8.51 mm2) gradually decreased. No obvious adverse reactions (fever, edema, pain, skin itching, rash, or other sensory abnormalities) were observed in either the au-PRP or the al-PRP groups. Both al-PRP and au-PRP could effectively and safely promote wound healing in patients with DLEUs. Alternatively, al-PRP could be used for DLEUs as an off-the-shelf solution when au-PRP is limited. Registration number of clinical trials: ChiCTR1900021317

scholarly journals P.R.L. Platelet Rich Lipotransfert: Our Experience and Current State of Art in the Combined Use of Fat and PRP

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
V. Cervelli ◽  
I. Bocchini ◽  
C. Di Pasquali ◽  
B. De Angelis ◽  
G. Cervelli ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Platelet Rich Plasma ◽  
Soft Tissue Defect ◽  
Fat Grafting ◽  
Promising Alternative ◽  
Hemifacial Atrophy ◽  
Innovative Methods ◽  
Current State ◽  
Combined Use ◽  
Natural Healing

The authors report their experience about the use of P.R.L. PLATELET RICH LIPOTRANSFERT method (platelet rich plasma mixed fat grafting) in 223 patients affected by soft tissue defects (ulcers, Romberg syndrome, Hemifacial atrophy, loss of substance, and signs of aging). This paper introduces the reader to PRP therapy and reviews the current literature on this emerging treatment modality, showing at the current clinical use of PRP in plastic and reconstructive surgery, with description of innovative methods and future prospects. This technique provides a promising alternative to surgery by promoting safe and natural healing. Here recent studies concerning the use of PRP in the treatment of chronic ulcers and soft tissue defect are reviewed.

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