scholarly journals META Score: An International Consensus Scoring System on Mesh-Tissue Adhesions

2020 ◽  
Vol 44 (9) ◽  
pp. 2935-2943
Author(s):  
L. C. L. van den Hil ◽  
E. H. H. Mommers ◽  
J. W. A. M. Bosmans ◽  
S. Morales-Conde ◽  
V. Gómez-Gil ◽  
...  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Tarek Sulaiman ◽  
Sai Medi ◽  
Hakan Erdem ◽  
Seniha Senbayrak ◽  
Derya Ozturk-Engin ◽  
...  

Abstract Background Tuberculous meningitis (TBM) represents a diagnostic and management challenge to clinicians. The “Thwaites’ system” and “Lancet consensus scoring system” are utilized to differentiate TBM from bacterial meningitis but their utility in subacute and chronic meningitis where TBM is an important consideration is unknown. Methods A multicenter retrospective study of adults with subacute and chronic meningitis, defined by symptoms greater than 5 days and less than 30 days for subacute meningitis (SAM) and greater than 30 days for chronic meningitis (CM). The “Thwaites’ system” and “Lancet consensus scoring system” scores and the diagnostic accuracy by sensitivity, specificity, and area under the curve of receiver operating curve (AUC-ROC) were calculated. The “Thwaites’ system” and “Lancet consensus scoring system” suggest a high probability of TBM with scores ≤4, and with scores of ≥12, respectively. Results A total of 395 patients were identified; 313 (79.2%) had subacute and 82 (20.8%) with chronic meningitis. Patients with chronic meningitis were more likely caused by tuberculosis and had higher rates of HIV infection (P < 0.001). A total of 162 patients with TBM and 233 patients with non-TBM had unknown (140, 60.1%), fungal (41, 17.6%), viral (29, 12.4%), miscellaneous (16, 6.7%), and bacterial (7, 3.0%) etiologies. TMB patients were older and presented with lower Glasgow coma scores, lower CSF glucose and higher CSF protein (P < 0.001). Both criteria were able to distinguish TBM from bacterial meningitis; only the Lancet score was able to differentiate TBM from fungal, viral, and unknown etiologies even though significant overlap occurred between the etiologies (P < .001). Both criteria showed poor diagnostic accuracy to distinguish TBM from non-TBM etiologies (AUC-ROC was <. 5), but Lancet consensus scoring system was fair in diagnosing TBM (AUC-ROC was .738), sensitivity of 50%, and specificity of 89.3%. Conclusion Both criteria can be helpful in distinguishing TBM from bacterial meningitis, but only the Lancet consensus scoring system can help differentiate TBM from meningitis caused by fungal, viral and unknown etiologies even though significant overlap occurs and the overall diagnostic accuracy of both criteria were either poor or fair.


2011 ◽  
Vol 07 (01) ◽  
pp. 76 ◽  
Author(s):  
Sonata Saulyte Trakymiene ◽  

Repeated bleeding into the joints leads to the development of chronic and progressive joint disease in 90% of people with severe haemophilia. Owing to recurrent haemarthroses, musculoskeletal outcome remains an important hallmark of treatment efficacy in haemophilia. Physical joint assessment is commonly used to measure structural and functional joint damage. With the development and introduction of prophylaxis, the most widely used instruments for the assessment of haemophilic arthropathy were found to lack sensitivity to detect the earliest signs of joint disease. To address these inadequacies, a new international consensus tool, the Haemophilia Joint Health Score (HJHS), was developed. The HJHS appears to be a sensitive, reliable and valid tool. However, the HJHS needs further evaluation in various patient populations to assess its applicability and usefulness.


2021 ◽  
Author(s):  
Tsz Hei Fong ◽  
Wangpan Shi ◽  
Siyi Li ◽  
Guanghui Liu ◽  
Chung Lam Ng ◽  
...  

This study aimed to validate the value of tuberculostearic acid (TBSA) whether it could implicate the existence of M. tuberculosis and assist for clinical diagnosis of Tuberculous Meningitis (TBM). Gas Chromatography/mass spectrometry was used to detect TBSA in the chemically pretreated cerebrospinal fluid of suspected TBM patients. In total, 140 patients were admitted for our study included 27 confirm TBM patients and 50 TBSA positive patients. Sensitivity of 0.7407 (CI 95%: 0.5372-0.8889) and specificity of 0.7345 (CI 95%: 0.6432-0.8132) were calculated. The Lancet consensus scoring system was also applied to evaluate the possibility of TBM in suspected patients, finding that TBSA positive patients showed a similar distributive grouping as the definite TBM patients. Our study implicates that the prospective use of TBSA is worth combining into a scoring system for characterizing the features of Mtb, showing a great potential of TBM diagnosis by TBSA in the future.


1979 ◽  
Vol 10 (4) ◽  
pp. 241-245
Author(s):  
Richard J. Schissel ◽  
Linda B. James

This study examines the assumptions underlying the scoring system of the Arizona Articulation Proficiency Scale: Revised. Twenty-one children between the ages of four years two months and six years 11 months were administered the Arizona Articulation Proficiency Scale: Revised and the Screening Deep Test of Articulation. The subjects' performance on the two tests was compared for the phones: [s], [l], [r], [t∫], [θ], [∫], [k], [f], and [t]. Results suggested that 1) the production of most sounds in only two contexts does not necessarily reflect the accuracy of production of those sounds in other contexts, and 2) for the sounds tested, the weightings assigned on the basis of their frequency of occurrence rather than the frequency with which they were misarticulated overestimated the extent of many articulation errors.


VASA ◽  
2012 ◽  
Vol 41 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Hoerth ◽  
Kundi ◽  
Katzenschlager ◽  
Hirschl

Background: Nailfold capillaroscopy (NVC) is a diagnostic tool particularly useful in the differential diagnosis of rheumatic and connective tissue diseases. Although successfully applied since many years, little is known about prevalence and distribution of NVC changes in healthy individuals. Probands and methods: NVC was performed in 120 individuals (57 men and 63 women; age 18 to 70 years) randomly selected according to predefined age and sex strata. Diseases associated with NVC changes were excluded. The nailfolds of eight fingers were assessed according to standardized procedures. A scoring system was developed based on the distribution of the number of morphologically deviating capillaries, microhaemorrhages, and capillary density. Results: Only 18 individuals (15 %) had no deviation in morphology, haemorrhages, or capillary density on any finger. Overall 67 % had morphological changes, 48 % had microhaemorrhages, and 40 % of volunteers below 40 years of age and 18 % above age 40 had less than 8 capillaries/mm. Among morphological changes tortous (43 %), ramified (47 %), and bushy capillaries (27 %) were the most frequently altered capillary types. A semiquantitative scoring system was developed in such a way that a score above 1 indicates an extreme position (above the 90th percentile) in the distribution of scores among healthy individuals. Conclusions: Altered capillaries occur frequently among healthy individuals and should be interpreted as normal unless a suspicious increase in their frequency is determined by reference to the scoring system. Megacapillaries and diffuse loss of capillaries were not found and seem to be of specific diagnostic value.


Author(s):  
Christoph Mischo ◽  
Katrin Wolstein ◽  
Svenja Peters

Zusammenfassung. Die Professionelle Wahrnehmung von Pädagoginnen und Pädagogen als Fähigkeit zur Identifikation, Interpretation und Bewertung relevanter Merkmale pädagogischer Interaktion stellt eine wichtige pädagogische Teilkompetenz dar. Empirisch untersucht ist die Professionelle Wahrnehmung insbesondere bei Lehrkräften, kaum dagegen bei Fachkräften in KiTas. Ziel dieser Studie ist daher die Untersuchung von Zusammenhängen zwischen der Professionellen Wahrnehmung und dem beobachteten Handeln von KiTa-Fachkräften. Zur Evokation der Professionellen Wahrnehmung wurden 120 Teilnehmerinnen und Teilnehmern typische Fachkraft-Kind-Interaktionen als Video-Stimuli dargeboten. Die Erfassung der Professionellen Wahrnehmung erfolgte mit zwei offenen (Lautes Denken und retrospektives Interview) sowie mit einem geschlossenen Antwortformat (Rating-Skalen). Zur Einschätzung der Qualität des Interaktionsverhaltens der Fachkräfte wurde das international gut etablierte Classroom Assessment Scoring System (CLASS Pre-K) eingesetzt. Bei der Zusammenhangsprüfung im Rahmen eines Strukturgleichungsmodells mit latenten Variablen zeigte nur die mit der Methode des Lauten Denkens erfasste Professionelle Wahrnehmung Zusammenhänge mit den CLASS-Domänen Organisation des KiTA-Alltags und Lernunterstützung. Die Ergebnisse werden im Hinblick auf die Implikationen der Erhebungsmethodik für die Professionelle Wahrnehmung diskutiert.


2016 ◽  
Vol 5 (4) ◽  
pp. 206-213 ◽  
Author(s):  
Andreas Wildgruber ◽  
Monika Wertfein ◽  
Claudia Wirts ◽  
Marina Kammermeier ◽  
Erik Danay

Zusammenfassung. Die Interaktionen zwischen pädagogischen Fachkräften und Kindern sind von zentraler Bedeutung für die Moderation des kindlichen Lernens und der kindlichen Entwicklung. Angesichts der Variabilität der Interaktionen im Tagesverlauf wurde in dieser explorativen Studie untersucht, inwieweit sich Unterschiede der Interaktionsqualität zwischen verschiedenen typischen Situationen (Freispiel, moderierte Aktivitäten, Lesesituationen, Garten, Essen) in Kindertageseinrichtungen zeigen. Bei 85 Fachkräften in bayerischen Kindergärten wurden die Interaktionen zwischen Fachkräften und Kindern jeweils einen Vormittag teilnehmend beobachtet und mit dem Verfahren „Classroom Assessment Scoring System Pre-K“ ( Pianta, La Paro & Hamre, 2008 ) geratet. Es zeigte sich zum einen in Essenssituationen eine niedrigere Interaktionsqualität als in den anderen Situationen. Zum anderen fand sich vor allem im Bereich der Lernunterstützung in Lesesituationen und moderierten Aktivitäten eine höhere Interaktionsqualität als im Freispiel. Die simultane Berücksichtigung der beiden Faktoren Tageszeit und Situation ergab, dass die gefundenen Effekte auf den Faktor Situation zurückzuführen waren.


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