Rapid study assessment in follow-up whole-body computed tomography in patients with multiple myeloma using a dedicated bone subtraction software

2020 ◽  
Vol 30 (6) ◽  
pp. 3198-3209
Author(s):  
M. M. Sieren ◽  
F. Brenne ◽  
A. Hering ◽  
H. Kienapfel ◽  
N. Gebauer ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Multiple Myeloma ◽  
Whole Body ◽  
Whole Body Computed Tomography

scholarly journals Imaging of Multiple Myeloma

2019 ◽  
Vol 191 (09) ◽  
pp. 805-816
Author(s):  
Aleksander Kosmala ◽  
Thorsten Bley ◽  
Bernhard Petritsch
Keyword(s):  
Computed Tomography ◽  
Multiple Myeloma ◽  
Bone Marrow ◽  
Imaging Techniques ◽  
Therapy Monitoring ◽  
Whole Body ◽  
Emission Computed Tomography ◽  
Cross Sectional ◽  
Therapeutic Implications

Background Multiple myeloma is a malignant hematological disease characterized by uncontrolled proliferation of monoclonal plasma cells mainly in the bone marrow. Imaging plays a crucial role in diagnosis and follow-up. Method This literature review provides information about multiple myeloma, its precursor diseases, and available imaging techniques. Advantages and limitations as well as possible prognostic and therapeutic implications of the different imaging methods are presented in the context of the current literature. Results and Conclusion Cross-sectional imaging has replaced conventional X-ray skeletal survey. Widely available whole-body computed tomography is routinely used to detect osteolytic lesions. Magnetic resonance imaging is the most sensitive technique to identify bone marrow infiltration and is recommended in multiple myeloma precursor diseases. Positron emission computed tomography combines morphological and functional imaging. It is mainly used for follow-up, therapy monitoring, and response evaluation. Key points:  Citation Format

scholarly journals Incidental Findings on Whole-body Computed Tomography in Major Trauma Patients: Who and What?

2021 ◽  
pp. 000313482199868
Author(s):  
Ping-Yuan Liu ◽  
Ling-Wei Kuo ◽  
Chien-Hung Liao ◽  
Chi-Hsun Hsieh ◽  
Francesco Bajani ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Incidental Findings ◽  
Major Trauma ◽  
Neck Region ◽  
Whole Body ◽  
Trauma Patients ◽  
Computed Tomography Images ◽  
Whole Body Computed Tomography ◽  
Head Neck

Purpose Whole-body computed tomography (WBCT) scans are frequently used for trauma patients, and sometimes, nontraumatic findings are observed. We aimed to investigate the characteristics of patients with nontraumatic findings on WBCT. Methods From 2013 to 2016, adult trauma patients who underwent WBCT were enrolled. The proportions of nontraumatic findings in different anatomical regions were studied. Nontraumatic findings were classified and evaluated as clinically important findings and findings that needed no further follow-up or treatment. The characteristics of the patients with nontraumatic findings were analyzed and compared with those of patients without nontraumatic findings. Results Two hundred seventeen patients were enrolled in this study during the 3-year study period, and 89 (41.0%) patients had nontraumatic findings. Nontraumatic findings were found more frequently in the abdomen (69.2%) than in the head/neck (17.3%) and chest regions (13.5%). In total, 31.3% of the findings needed further follow-up or treatment. Patients with nontraumatic findings that needed further management were significantly older than those without nontraumatic findings (57.3 vs. 38.9; P < .001), particularly those with abdominal nontraumatic findings (57.9 vs. 41.3; P < .001). A significantly higher proportion of women were observed in the group with head/neck nontraumatic findings that needed further management than in the group without nontraumatic findings (56.3% vs 24.9%; P = .015). Conclusions Whole-body computed tomography could provide alternative benefits for nontraumatic findings. Whole-body computed tomography images should be read carefully for nontraumatic findings, particularly for elderly patients or the head/neck region of female patients. A comprehensive program for the follow-up of nontraumatic findings is needed.

The benefit of using whole-body, low-dose, nonenhanced, multidetector computed tomography for follow-up and therapy response monitoring in patients with multiple myeloma

Cancer ◽  
2007 ◽  
Vol 109 (8) ◽  
pp. 1617-1626 ◽  
Author(s):  
Marius Horger ◽  
Lothar Kanz ◽  
Barbara Denecke ◽  
Reinhard Vonthein ◽  
Philippe Pereira ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Multiple Myeloma ◽  
Multidetector Computed Tomography ◽  
Low Dose ◽  
Therapy Response ◽  
Whole Body ◽  
Response Monitoring

scholarly journals Incidental Findings on Whole-body Computed Tomography in Major Trauma Patients: Who and What?

2020 ◽  
Author(s):  
Ping-Yuan Liu ◽  
Ling-Wei Kuo ◽  
Chien-Hung Liao ◽  
Chi-Hsun Hsieh ◽  
Francesco Bajani ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Incidental Findings ◽  
Major Trauma ◽  
Neck Region ◽  
Whole Body ◽  
Trauma Patients ◽  
Whole Body Computed Tomography ◽  
Head Neck ◽  
Thyroid Lesions

Abstract Background The use of whole-body computed tomography (WBCT) scans has greatly increased in the management of patients with major trauma. Sometimes, nontraumatic findings on WBCT are observed. In the current study, we aimed to investigate the proportion of nontraumatic findings on WBCT in major trauma patients and the characteristics of patients with nontraumatic findings on WBCT.Methods From June 2013 to May 2016, adult trauma patients who received WBCT were enrolled. The proportions of nontraumatic findings in different anatomical regions were studied. Nontraumatic findings were classified and evaluated as clinically important findings and findings that did not need further follow-up or treatment. The characteristics of patients with nontraumatic findings were analyzed and compared with those of patients without nontraumatic findings.Results A total of 217 patients were enrolled in this study during the 3-year study period, and 89 (41.0%) patients had nontraumatic findings. Nontraumatic findings were found more frequently in the abdomen (69.2%) than in the head/neck (17.3%) and chest regions (13.5%). In total, 31.3% of the findings needed further follow-up or treatment. Patients with nontraumatic findings that needed further management were significantly older than patients without nontraumatic findings (57.3 vs. 38.9, p<0.001), especially those with abdominal nontraumatic findings (57.9 vs. 41.3, p<0.001). A significantly higher proportion of females was observed in the group with head/neck nontraumatic findings that needed further management than in the group without nontraumatic findings (56.3% vs. 24.9%, p=0.015).Conclusions WBCT could provide alternative benefits for nontraumatic findings. The WBCT images should be read carefully for nontraumatic findings, especially for elderly patients. For female patients, the head/neck region should be carefully evaluated with WBCT for possible thyroid lesions. A comprehensive program for the follow-up of nontraumatic findings is needed.

scholarly journals Correlation of age, sex and season with the state of human decomposition as quantified by postmortem computed tomography

2021 ◽  
Author(s):  
Dominic L. C. Guebelin ◽  
Akos Dobay ◽  
Lars Ebert ◽  
Eva Betschart ◽  
Michael J. Thali ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Demographic Data ◽  
Sociodemographic Factors ◽  
The State ◽  
The Body ◽  
Seasonal Effects ◽  
Whole Body ◽  
Postmortem Computed Tomography ◽  
Whole Body Computed Tomography ◽  
Urban Study

AbstractDead bodies exhibit a variable range of changes with advancing decomposition. To quantify intracorporeal gas, the radiological alteration index (RAI) has been implemented in the assessment of postmortem whole-body computed tomography. We used this RAI as a proxy for the state of decomposition. This study aimed to (I) investigate the correlation between the state of decomposition and the season in which the body was discovered; and (II) evaluate the correlations between sociodemographic factors (age, sex) and the state of decomposition, by using the RAI as a proxy for the extent of decomposition. In a retrospective study, we analyzed demographic data from all autopsy reports from the Institute of Forensic Medicine of Zurich between January 2017 to July 2019 and evaluated the radiological alteration index from postmortem whole-body computed tomography for each case. The bodies of older males showed the highest RAI. Seasonal effects had no significant influence on the RAI in our urban study population with bodies mostly being discovered indoors. Autopsy reports contain valuable data that allow interpretation for reasons beyond forensic purposes, such as sociopolitical observations.

scholarly journals Outcomes of whole-body computed tomography in spinal cord-injured patients with sepsis

Spinal Cord ◽  
2014 ◽  
Vol 52 (7) ◽  
pp. 536-540 ◽  
Author(s):  
W A Ahmed ◽  
L L de Heredia ◽  
R J Hughes ◽  
M Belci ◽  
T M Meagher
Keyword(s):  
Computed Tomography ◽  
Spinal Cord ◽  
Whole Body ◽  
Whole Body Computed Tomography ◽  
Injured Patients ◽  
Spinal Cord Injured

Whole-body computed tomography in polytrauma: techniques and management

2001 ◽  
Vol 12 (7) ◽  
pp. 1728-1740 ◽  
Author(s):  
Ulrich Linsenmaier ◽  
Michael Krötz ◽  
Hannes Häuser ◽  
Clemens Rock ◽  
Johannes Rieger ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Whole Body ◽  
Whole Body Computed Tomography
Sign in / Sign up

Export Citation Format

Share Document