Seeded precipitation polymerization for the synthesis of gold-hydrogel core-shell particles: the role of surface functionalization and seed concentration

2015 ◽  
Vol 294 (1) ◽  
pp. 37-47 ◽  
Author(s):  
Astrid Rauh ◽  
Tobias Honold ◽  
Matthias Karg
Polymers ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 3471
Author(s):  
Se Min Kim ◽  
Madhumita Patel ◽  
Rajkumar Patel

Core–shell particles are very well known for their unique features. Their distinctive inner core and outer shell structure allowed promising biomedical applications at both nanometer and micrometer scales. The primary role of core–shell particles is to deliver the loaded drugs as they are capable of sequence-controlled release and provide protection of drugs. Among other biomedical polymers, poly (lactic-co-glycolic acid) (PLGA), a food and drug administration (FDA)-approved polymer, has been recognized for the vehicle material. This review introduces PLGA core–shell nano/microparticles and summarizes various drug-delivery systems based on these particles for cancer therapy and tissue regeneration. Tissue regeneration mainly includes bone, cartilage, and periodontal regeneration.


2006 ◽  
Vol 988 ◽  
Author(s):  
Yi-Yeoun Kim ◽  
John W Catino ◽  
Gary P Tomaino ◽  
Sherman D Cox

AbstractIn this report, we present a bio-inspired encapsulation process to create nanocluster-assembled core-shell particles under aqueous, room temperature and non-toxic conditions. The approach to synthesize calcium carbonate core-shell particles is accomplished by employing a Polymer-Induced Liquid-Precursor (PILP) process. We demonstrate the amorphous mineral precursor is coated around a core of hydrogel nanoparticles, and subsequently solidified and crystallized. The synthesized core-shell particles are 300∼500nm diameter and ∼100 nm shell-thickness. We investigate the role of the hydrogel core of the particle using time-resolved XRD, thermal-XRD and thermal analysis. The organic hydrogel appears to influence the transformation of mineral phases, stabilizing the amorphous phase of calcium carbonate.


2010 ◽  
Vol 604 (23-24) ◽  
pp. 2116-2128 ◽  
Author(s):  
Hyunwook Kwak ◽  
Santanu Chaudhuri

2012 ◽  
Vol 155 ◽  
pp. 8-13 ◽  
Author(s):  
Milan P. Nikolić ◽  
Konstantinos P. Giannakopoulos ◽  
Miloš Bokorov ◽  
Vladimir V. Srdić

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